Featured Research

from universities, journals, and other organizations

Different eggs in adolescent girls, adult women

Date:
February 26, 2014
Source:
University of Gothenburg
Summary:
Are the eggs produced by adolescent girls the same as the ones produced by adult women? A recent study shows compelling evidence that there are two completely distinct types of eggs in the mammalian ovary -- 'the first wave' and 'the adult wave.' The first wave of eggs, which starts immediately after birth, contributes to the onset of puberty and provides fertilizable eggs into the transition from adolescence to adulthood. In contrast, the adult wave remains in a state of dormancy until activated during the adult life and then provides eggs throughout the entire reproductive lifespan.

This is the first time that the developmental dynamics of two distinct populations of eggs have been clearly described in an animal model, and there is evidence that these two waves of eggs most likely also exist in the human ovary.
Credit: Image courtesy of University of Gothenburg

Are the eggs produced by adolescent girls the same as the ones produced by adult women? A recent study published in Human Molecular Genetics by Professor Kui Liu from the University of Gothenburg in Sweden shows compelling evidence that there are two completely distinct types of eggs in the mammalian ovary -- "the first wave" and "the adult wave."

Professor Liu's team used two genetically modified mouse models to show that the first wave of eggs, which starts immediately after birth, contributes to the onset of puberty and provides fertilizable eggs into the transition from adolescence to adulthood. In contrast, the adult wave remains in a state of dormancy until activated during the adult life and then provides eggs throughout the entire reproductive lifespan.

This is the first time that the developmental dynamics of two distinct populations of eggs have been clearly described in an animal model, and there is evidence that these two waves of eggs most likely also exist in the human ovary. The identification and characterization of the two waves of eggs will lead to new ways of thinking about how to obtain the best eggs when treating women for ovarian diseases that cause infertility. Such techniques will prove especially useful for women suffering from premature ovarian failure (POF), which affects 1%-4% of all women of childbearing age. The results may also lead to more effective treatments for ovarian diseases by specifically targeting the different egg populations.


Story Source:

The above story is based on materials provided by University of Gothenburg. The original article was written by Carina Eliasson. Note: Materials may be edited for content and length.


Journal Reference:

  1. W. Zheng, H. Zhang, N. Gorre, S. Risal, Y. Shen, K. Liu. Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions. Human Molecular Genetics, 2013; 23 (4): 920 DOI: 10.1093/hmg/ddt486

Cite This Page:

University of Gothenburg. "Different eggs in adolescent girls, adult women." ScienceDaily. ScienceDaily, 26 February 2014. <www.sciencedaily.com/releases/2014/02/140226101817.htm>.
University of Gothenburg. (2014, February 26). Different eggs in adolescent girls, adult women. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2014/02/140226101817.htm
University of Gothenburg. "Different eggs in adolescent girls, adult women." ScienceDaily. www.sciencedaily.com/releases/2014/02/140226101817.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins