Featured Research

from universities, journals, and other organizations

DNA can be damaged by very low-energy radiation

Date:
March 14, 2014
Source:
Tata Institute of Fundamental Research
Summary:
That energetic particles damage DNA is not surprising. It is now appears that very low-energy OH radicals also damage DNA, with a propensity that depends on how vigorously OH rotates: rotationally 'hot' OH induce irreparable double breaks. These findings utilize OH formed in plasma created when intense IR femtosecond laser pulses propagate in water containing DNA. Industry characterizes as 'eye-safe' IR lasers. With such wavelengths being proficient at inducing DNA damage, how safe is 'eye-safe'?

Damage to DNA by high energy radiation constitutes the most lethal damage occurring at the cellular level. Surprisingly, very low-energy interactions -- with OH radicals, for instance -- can also induce DNA damage, including double strand breaks.

Related Articles


It is known that single strand breaks in the DNA backbone are amenable to repair but most double strand breaks are irreparable. The propensity with which slow OH radicals damage DNA depends on their rotational energy: rotationally "hot" OH is more proficient in causing double breaks.

These novel findings are from experiments conducted on DNA in a physiological environment. Intense femtosecond laser pulses are propagated through water (in which DNA plasmids are suspended), creating plasma channels within water, resulting in generation, in situ, of electrons and OH radicals. It is shown that use of long laser wavelength light (1350 nm and 2200 nm) ensures only OH-induced damage to DNA is accessed.

It is noteworthy that industry presently characterizes as "eye-safe" lasers that emit at wavelengths longer than 1300 nm.

But it is such wavelengths that are proficient at inducing damage to DNA: how safe is "eye-safe" when DNA in the eye can be readily damaged?


Story Source:

The above story is based on materials provided by Tata Institute of Fundamental Research. Note: Materials may be edited for content and length.


Cite This Page:

Tata Institute of Fundamental Research. "DNA can be damaged by very low-energy radiation." ScienceDaily. ScienceDaily, 14 March 2014. <www.sciencedaily.com/releases/2014/03/140314093729.htm>.
Tata Institute of Fundamental Research. (2014, March 14). DNA can be damaged by very low-energy radiation. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2014/03/140314093729.htm
Tata Institute of Fundamental Research. "DNA can be damaged by very low-energy radiation." ScienceDaily. www.sciencedaily.com/releases/2014/03/140314093729.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com
Ebola Fears Keep Guinea Hospitals Empty

Ebola Fears Keep Guinea Hospitals Empty

AP (Oct. 23, 2014) Fears of Ebola are keeping doctors and patients alike away from hospitals in the West African nation of Guinea. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Despite Rising Death Toll, Many Survive Ebola

Despite Rising Death Toll, Many Survive Ebola

AP (Oct. 23, 2014) The family of a Dallas nurse infected with Ebola in the US says doctors can no longer detect the virus in her. Despite the mounting death toll in West Africa, there are survivors there too. (Oct. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins