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Body temperature linked to relapsing-remitting MS, fatigue

Date:
March 18, 2014
Source:
Kessler Foundation
Summary:
Body temperature is elevated endogenously in relapsing-remitting multiple sclerosis and linked to worse fatigue, researchers have demonstrated for the first time. "We found that body temperature was elevated among patients with RRMS and linked to worse fatigue," reported the authors.

Kessler Foundation researchers have demonstrated for the first time ever that body temperature is elevated endogenously in relapsing-remitting multiple sclerosis (RRMS) and linked to worse fatigue. The article was published ahead of print on Feb. 21, 2014 in Archives of Physical Medicine & Rehabilitation.

Researchers measured body temperature in 50 patients with RRMS, 40 matched healthy controls, and 22 patients with secondary progressive MS (SPMS). They looked at whether resting body temperature was elevated in patients with RRMS and whether elevation was linked to fatigue, a prevalent, disabling, and recalcitrant symptom in this population.

"We found that body temperature was elevated among patients with RRMS and linked to worse fatigue," reported Dr. Sumowski, research scientist in Neuropsychology & Neuroscience Research. "Our findings support those of randomized controlled trials of cooling garments and antipyretics, which have been shown to effectively reduce fatigue in MS. More studies are needed to investigate the complex relationships among fatigue, body temperature and inflammatory processes in RRMS."


Story Source:

The above story is based on materials provided by Kessler Foundation. Note: Materials may be edited for content and length.


Journal Reference:

  1. James F. Sumowski, Victoria M. Leavitt. Body temperature is elevated and linked to fatigue in relapsing-remitting multiple sclerosis, even without heat exposure. Archives of Physical Medicine and Rehabilitation, 2014; DOI: 10.1016/j.apmr.2014.02.004

Cite This Page:

Kessler Foundation. "Body temperature linked to relapsing-remitting MS, fatigue." ScienceDaily. ScienceDaily, 18 March 2014. <www.sciencedaily.com/releases/2014/03/140318154933.htm>.
Kessler Foundation. (2014, March 18). Body temperature linked to relapsing-remitting MS, fatigue. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2014/03/140318154933.htm
Kessler Foundation. "Body temperature linked to relapsing-remitting MS, fatigue." ScienceDaily. www.sciencedaily.com/releases/2014/03/140318154933.htm (accessed July 26, 2014).

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