Featured Research

from universities, journals, and other organizations

Novel resuscitation strategy for babies with birth asphyxia

Date:
April 3, 2014
Source:
Helsingin yliopisto (University of Helsinki)
Summary:
During birth, the baby has to stop depending on the placenta and start breathing on his or her own. If there are problems during the birth process, the baby may spend a period of time in the pathological condition of asphyxia, where the oxygen levels in the blood are much lower and carbon dioxide levels are much higher than expected. A doctoral dissertation focuses on a new strategy to deal with this situation.

During birth, the baby has to stop depending on the placenta and start breathing on his or her own. If there are problems during the birth process, the baby may spend a period of time in the pathological condition of asphyxia, where the oxygen levels in the blood are much lower and carbon dioxide levels are much higher than expected.

Birth asphyxia is the most common cause of seizures in newborn babies. Birth asphyxia seizures tend to cause problems later in life. The range of these problems is very wide, and include problems of movement and poor performance in school.

Gradual decrease of abnormally high carbon dioxide prevents seizures

Current resuscitation protocols for babies include strict instructions on how to control the oxygen the baby is breathing. Instructions on how to control carbon dioxide are, however, absent. When oxygen levels are quickly restored in babies after birth asphyxia, carbon dioxide levels are also quickly restored.

Mohamed Helmy in the Laboratory of Neurobiology, University of Helsinki, Finland, developed for his doctoral dissertation a rat model of birth asphyxia, the original idea of Prof. Kai Kaila. They found out that this quick restoration of carbon dioxide levels after birth asphyxia may in fact trigger seizures.

"In our new therapeutic strategy carbon dioxide levels were restored gradually after birth asphyxia and the rats had far fewer seizures. Restoring carbon dioxide levels after experimental birth asphyxia gradually also resulted in more favorable outcome of behavior in adult life when compared with rats in which carbon dioxide levels were restored quickly after experimental birth asphyxia," Mohamed Helmy explains.

The Laboratory of Neurobiology in the University of Helsinki, Finland, is now investigating the mechanisms underlying birth asphyxia seizures, and developing the proposed treatment further.

A copy of the dissertation can be found online at: https://helda.helsinki.fi/bitstream/handle/10138/43159/Helmy_dissertation.pdf?sequence=1


Story Source:

The above story is based on materials provided by Helsingin yliopisto (University of Helsinki). Note: Materials may be edited for content and length.


Cite This Page:

Helsingin yliopisto (University of Helsinki). "Novel resuscitation strategy for babies with birth asphyxia." ScienceDaily. ScienceDaily, 3 April 2014. <www.sciencedaily.com/releases/2014/04/140403084358.htm>.
Helsingin yliopisto (University of Helsinki). (2014, April 3). Novel resuscitation strategy for babies with birth asphyxia. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2014/04/140403084358.htm
Helsingin yliopisto (University of Helsinki). "Novel resuscitation strategy for babies with birth asphyxia." ScienceDaily. www.sciencedaily.com/releases/2014/04/140403084358.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins