Featured Research

from universities, journals, and other organizations

Novel resuscitation strategy for babies with birth asphyxia

Date:
April 3, 2014
Source:
Helsingin yliopisto (University of Helsinki)
Summary:
During birth, the baby has to stop depending on the placenta and start breathing on his or her own. If there are problems during the birth process, the baby may spend a period of time in the pathological condition of asphyxia, where the oxygen levels in the blood are much lower and carbon dioxide levels are much higher than expected. A doctoral dissertation focuses on a new strategy to deal with this situation.

During birth, the baby has to stop depending on the placenta and start breathing on his or her own. If there are problems during the birth process, the baby may spend a period of time in the pathological condition of asphyxia, where the oxygen levels in the blood are much lower and carbon dioxide levels are much higher than expected.

Birth asphyxia is the most common cause of seizures in newborn babies. Birth asphyxia seizures tend to cause problems later in life. The range of these problems is very wide, and include problems of movement and poor performance in school.

Gradual decrease of abnormally high carbon dioxide prevents seizures

Current resuscitation protocols for babies include strict instructions on how to control the oxygen the baby is breathing. Instructions on how to control carbon dioxide are, however, absent. When oxygen levels are quickly restored in babies after birth asphyxia, carbon dioxide levels are also quickly restored.

Mohamed Helmy in the Laboratory of Neurobiology, University of Helsinki, Finland, developed for his doctoral dissertation a rat model of birth asphyxia, the original idea of Prof. Kai Kaila. They found out that this quick restoration of carbon dioxide levels after birth asphyxia may in fact trigger seizures.

"In our new therapeutic strategy carbon dioxide levels were restored gradually after birth asphyxia and the rats had far fewer seizures. Restoring carbon dioxide levels after experimental birth asphyxia gradually also resulted in more favorable outcome of behavior in adult life when compared with rats in which carbon dioxide levels were restored quickly after experimental birth asphyxia," Mohamed Helmy explains.

The Laboratory of Neurobiology in the University of Helsinki, Finland, is now investigating the mechanisms underlying birth asphyxia seizures, and developing the proposed treatment further.

A copy of the dissertation can be found online at: https://helda.helsinki.fi/bitstream/handle/10138/43159/Helmy_dissertation.pdf?sequence=1


Story Source:

The above story is based on materials provided by Helsingin yliopisto (University of Helsinki). Note: Materials may be edited for content and length.


Cite This Page:

Helsingin yliopisto (University of Helsinki). "Novel resuscitation strategy for babies with birth asphyxia." ScienceDaily. ScienceDaily, 3 April 2014. <www.sciencedaily.com/releases/2014/04/140403084358.htm>.
Helsingin yliopisto (University of Helsinki). (2014, April 3). Novel resuscitation strategy for babies with birth asphyxia. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2014/04/140403084358.htm
Helsingin yliopisto (University of Helsinki). "Novel resuscitation strategy for babies with birth asphyxia." ScienceDaily. www.sciencedaily.com/releases/2014/04/140403084358.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins