Featured Research

from universities, journals, and other organizations

Dopamine, hippocampus and psychiatric diseases: Clarifying their relationships

Date:
April 3, 2014
Source:
Douglas Mental Health University Institute
Summary:
The role that dopamine plays in a region of the brain called the hippocampus has been demonstrated for the first time. Dopamine is a neurotransmitter that plays a central role in brain function, and many mental illnesses involve an imbalance in this chemical. Research has shown in particular that dopamine is present in the hippocampus -- the brain area associated with memory and learning -- and that it plays a key role in this region.

Bruno Giros, PhD, a researcher at the Douglas Mental Health University Institute and a professor in the Department of Psychiatry at McGill University, has demonstrated, for the first time, the role that dopamine plays in a region of the brain called the hippocampus. Published in Biological Psychiatry, this discovery opens the door to a better understanding of psychiatric diseases, such as schizophrenia.

Dopamine is a neurotransmitter that plays a central role in brain function, and many mental illnesses involve an imbalance in this chemical. What Bruno Giros has shown in particular is that dopamine is present in the hippocampus -- the brain area associated with memory and learning -- and that it plays a key role in this region.

"Our work helps us better understand some of the symptoms of schizophrenia for which the cause in the brain was unknown, particularly in the area of memory and learning. In a few years, this research could help researchers come up with new therapeutic approaches to improve these symptoms," explained Bruno Giros.


Story Source:

The above story is based on materials provided by Douglas Mental Health University Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jill Rocchetti, Elsa Isingrini, Gregory Dal Bo, Sara Sagheby, Aurore Menegaux, Franηois Tronche, Daniel Levesque, Luc Moquin, Alain Gratton, Tak Pan Wong, Marcelo Rubinstein, Bruno Giros. Presynaptic D2 Dopamine Receptors Control LTD Expression and Memory Processes in the Temporal Hippocampus. Biological Psychiatry, 2014; DOI: 10.1016/j.biopsych.2014.03.013

Cite This Page:

Douglas Mental Health University Institute. "Dopamine, hippocampus and psychiatric diseases: Clarifying their relationships." ScienceDaily. ScienceDaily, 3 April 2014. <www.sciencedaily.com/releases/2014/04/140403132337.htm>.
Douglas Mental Health University Institute. (2014, April 3). Dopamine, hippocampus and psychiatric diseases: Clarifying their relationships. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2014/04/140403132337.htm
Douglas Mental Health University Institute. "Dopamine, hippocampus and psychiatric diseases: Clarifying their relationships." ScienceDaily. www.sciencedaily.com/releases/2014/04/140403132337.htm (accessed July 26, 2014).

Share This




More Mind & Brain News

Saturday, July 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) — An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com
Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins