Featured Research

from universities, journals, and other organizations

Atypical brain connectivity associated with autism spectrum disorder

Date:
April 16, 2014
Source:
The JAMA Network Journals
Summary:
Autism spectrum disorder in adolescents appears to be associated with atypical connectivity in the brain involving the systems that help people infer what others are thinking and understand the meaning of others' actions and emotions. The ability to navigate and thrive in complex social systems is commonly impaired in ASD, a neurodevelopmental disorder affecting as many as 1 in 88 children.

Autism spectrum disorder (ASD) in adolescents appears to be associated with atypical connectivity in the brain involving the systems that help people infer what others are thinking and understand the meaning of others' actions and emotions.

The ability to navigate and thrive in complex social systems is commonly impaired in ASD, a neurodevelopmental disorder affecting as many as 1 in 88 children.

The authors used functional magnetic resonance imaging to investigate connectivity in two brain networks involved in social processing: theory of mind (ToM, otherwise known as the mentalizing system, which allows an individual to infer what others are thinking, their beliefs, their intentions) and the mirror neuron system (MNS, which allows people to understand the meanings and actions of others by simulating and replicating them). The study included 25 adolescents with ASD (between the ages of 11 and 18) and 25 typically developing adolescents.

Compared to typically developing adolescents, those with ASD showed both over- and under-connectivity in the ToM network, which was associated with greater social impairment. The adolescents with ASD also had increased connectivity between the regions of the MNS and ToM, suggesting that ToM-MNS "cross talk" might be associated with social impairment.

"This excess ToM-MNS connectivity may reflect immature or aberrant developmental processes in two brain networks involved in understanding of others, a domain impairment in ASD. Further, robust links with sociocommunicative symptoms of ASD implicate atypically increased ToM-MNS connectivity in social deficits observed in ASD."


Story Source:

The above story is based on materials provided by The JAMA Network Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Inna Fishman, Christopher L. Keown, Alan J. Lincoln, Jaime A. Pineda, Ralph-Axel Mόller. Atypical Cross Talk Between Mentalizing and Mirror Neuron Networks in Autism Spectrum Disorder. JAMA Psychiatry, 2014; DOI: 10.1001/jamapsychiatry.2014.83

Cite This Page:

The JAMA Network Journals. "Atypical brain connectivity associated with autism spectrum disorder." ScienceDaily. ScienceDaily, 16 April 2014. <www.sciencedaily.com/releases/2014/04/140416172313.htm>.
The JAMA Network Journals. (2014, April 16). Atypical brain connectivity associated with autism spectrum disorder. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2014/04/140416172313.htm
The JAMA Network Journals. "Atypical brain connectivity associated with autism spectrum disorder." ScienceDaily. www.sciencedaily.com/releases/2014/04/140416172313.htm (accessed August 30, 2014).

Share This




More Mind & Brain News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Treadmill 'trips' May Reduce Falls for Elderly

Treadmill 'trips' May Reduce Falls for Elderly

AP (Aug. 28, 2014) — Scientists are tripping the elderly on purpose in a Chicago lab in an effort to better prevent seniors from falling and injuring themselves in real life. (Aug.28) Video provided by AP
Powered by NewsLook.com
Alice in Wonderland Syndrome

Alice in Wonderland Syndrome

Ivanhoe (Aug. 27, 2014) — It’s an unusual condition with a colorful name. Kids with “Alice in Wonderland” syndrome see sudden distortions in objects they’re looking at or their own bodies appear to change size, a lot like the main character in the Lewis Carroll story. Video provided by Ivanhoe
Powered by NewsLook.com
Stopping Schizophrenia Before Birth

Stopping Schizophrenia Before Birth

Ivanhoe (Aug. 27, 2014) — Scientists have long called choline a “brain booster” essential for human development. Not only does it aid in memory and learning, researchers now believe choline could help prevent mental illness. Video provided by Ivanhoe
Powered by NewsLook.com
Personalized Brain Vaccine for Glioblastoma

Personalized Brain Vaccine for Glioblastoma

Ivanhoe (Aug. 27, 2014) — Glioblastoma is the most common and aggressive brain cancer in humans. Now a new treatment using the patient’s own tumor could help slow down its progression and help patients live longer. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins