Featured Research

from universities, journals, and other organizations

Multiple sclerosis: Review of current treatments for physicians

Date:
April 22, 2014
Source:
Canadian Medical Association Journal
Summary:
A review of the literature on treating multiple sclerosis aims to provide physicians with evidence-based information on the latest treatments for this chronic disease. The article looks at the latest pharmacologic research as well as disease-modifying agents and the benefits and risks of various treatments.

A review of the literature on treating multiple sclerosis (MS) aims to provide physicians with evidence-based information on the latest treatments for this chronic disease. The article, published in CMAJ (Canadian Medical Association Journal) looks at the latest pharmacologic research as well as disease-modifying agents and the benefits and risks of various treatments.

"Recently, several new compounds have been developed and approved with the aim of favourably changing the disease course, but with varied success," writes Dr. Loredana La Mantia, Cochrane Multiple Sclerosis Cochrane and Rare Diseases of the Central Nervous System Group, Milan Italy, with coauthors. "The evaluation of the effectiveness of treatments for MS is complex, and identifying the most appropriate treatment for an individual patient may be difficult."

Steroids are the most effective way of treating relapses, with intravenous use of methylprednisolone the usual treatment. A systematic review showed "that oral and intravenous administration of steroids may have similar efficacies" and "could have a substantial impact on clinical practice by allowing outpatient instead of hospital management of relapses in many instances," write the authors.

They discuss the benefits and risks of immunosuppressants such as natalizumab, fingolimod and others as well as new treatments under investigation.

"Several important areas of the pharmacologic management of MS need further investigation. The long-term efficacy of drug treatments is unknown in terms of the accumulation of disability and the prognosis of relapsing-remitting MS. A better understanding of the neuroprotective effects of available drugs and newer compounds is needed," the authors conclude.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. Tavazzi, M. Rovaris, L. La Mantia. Drug therapy for multiple sclerosis. Canadian Medical Association Journal, 2014; DOI: 10.1503/cmaj.130727

Cite This Page:

Canadian Medical Association Journal. "Multiple sclerosis: Review of current treatments for physicians." ScienceDaily. ScienceDaily, 22 April 2014. <www.sciencedaily.com/releases/2014/04/140422121231.htm>.
Canadian Medical Association Journal. (2014, April 22). Multiple sclerosis: Review of current treatments for physicians. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2014/04/140422121231.htm
Canadian Medical Association Journal. "Multiple sclerosis: Review of current treatments for physicians." ScienceDaily. www.sciencedaily.com/releases/2014/04/140422121231.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins