Featured Research

from universities, journals, and other organizations

All men with gout should be routinely screened for erectile dysfunction

Date:
June 12, 2014
Source:
European League Against Rheumatism
Summary:
Erectile dysfunction is present in most men with gout and is frequently severe. ED is a common problem in the general population, with the prevalence of moderate to severe ED estimated to between 5- 20%.2 The likelihood of ED increases progressively with age; however, it is not an inevitable consequence of aging. The importance of vascular disease as an underlying cause of ED is well established.

A new study presented at the European League Against Rheumatism Annual Congress (EULAR 2014) showed that erectile dysfunction (ED) is present in most men with gout and is frequently severe.

Related Articles


In a survey of 201 men, 83 had gout, of whom a significantly greater proportion had ED (76%) compared with those patients without gout (52%) (p= 0.0007). Also, a significantly greater proportion of gout patients (43%) had severe ED compared with patients without gout (30%) (p=0.007).1

According to lead author Dr. Naomi Schlesinger, Chief, Division of Rheumatology and Professor of Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, US, "these results strongly support the proposal to screen all men with gout for the presence of ED. Increasing awareness of the presence of ED in gout patients should in turn lead to earlier medical attention and treatment for this distressing condition," she added.

Gout is a condition characterized by recurrent attacks of acute inflammatory arthritis. Around 1- 4% of the Western population will develop gout at some point in their lifetime.2 The arthritis is caused by deposits of needle-like monosodium urate crystals in the joints and is associated with an abnormally high level of urate in the bloodstream. The crystals cause inflammation, swelling, and pain in the affected joint.

"Because gout is commonly associated with cardiovascular disease (CVD) risk factors and coronary artery disease (CAD) and patients who present with ED also have an increased rate of CVD risk factors and concomitant silent CAD, all these patients should also be evaluated for possible silent CAD," Dr. Schlesinger concluded.

ED is a common problem in the general population, with the prevalence of moderate to severe ED estimated to between 5- 20%.2 The likelihood of ED increases progressively with age; however, it is not an inevitable consequence of aging. The importance of vascular disease as an underlying cause of ED is well established.

In this cross sectional study, men aged 18-89 presenting to a Rheumatology clinic between August 2010 and May 2013 were asked to participate. The presence of ED was determined by filling out a Sexual Health Inventory in Men (SHIM). The SHIM classifies ED into one of five categories: absent (26), mild (22), mild to moderate (17), moderate (11) and severe (1). The patient's history, physical examination and recent laboratory studies were reviewed as well. Descriptive statistics and subgroup analyses were used to summarise the data. Chi-square tests for independence were used to compare categorical variables.

The mean SHIM score of all patients was 16.88 (SD±-0.83). Gout patients had an average SHIM score of 14.38 (SD±1.01) vs. 18.53 (SD± 0.964) in patients without gout (p < 0.0001). A significantly greater proportion of gout patients whose age was ≥ 65 had ED vs. patients without gout (p=0.0001) and it was significantly more likely to be severe ED vs. patients without gout (p=0.0002). A significantly greater proportion of patients with tophaceous gout had ED vs. those without tophi (p=0.0001). In a multivariate analysis, the association between gout and ED remained statistically significant even after adjusting for age (p=0.0009), hypertension, LDL-cholesterol, glomerular filtration rate (a measure of renal function), obesity, depression (p=0.0154) and diabetes (p=0.0085).


Story Source:

The above story is based on materials provided by European League Against Rheumatism. Note: Materials may be edited for content and length.


Cite This Page:

European League Against Rheumatism. "All men with gout should be routinely screened for erectile dysfunction." ScienceDaily. ScienceDaily, 12 June 2014. <www.sciencedaily.com/releases/2014/06/140612085757.htm>.
European League Against Rheumatism. (2014, June 12). All men with gout should be routinely screened for erectile dysfunction. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2014/06/140612085757.htm
European League Against Rheumatism. "All men with gout should be routinely screened for erectile dysfunction." ScienceDaily. www.sciencedaily.com/releases/2014/06/140612085757.htm (accessed March 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins