Featured Research

from universities, journals, and other organizations

A fifth of children visiting their doctor with a persistent cough could have whooping cough

Date:
June 24, 2014
Source:
BMJ-British Medical Journal
Summary:
Whooping cough has been found in a fifth of UK school age children visiting their doctor with a persistent cough, even though most have been fully vaccinated, a study finds. Whooping cough (pertussis) is a highly transmissible infection which can cause symptoms such as coughing, vomiting and whooping. However, whooping cough can lead to serious complications in unvaccinated infants.

Whooping cough has been found in a fifth of UK school age children visiting their doctor with a persistent cough, even though most have been fully vaccinated, finds a study published on bmj.com today.

Related Articles


Before the preschool pertussis booster vaccination had been introduced in the UK in 2001, evidence of recent pertussis infection could be found in nearly 40% of school age children who presented in primary care with a persistent cough.

These findings will help to inform consideration of the need for an adolescent booster vaccination in the UK.

Whooping cough (pertussis) is a highly transmissible infection which can cause symptoms such as coughing, vomiting and whooping. However, whooping cough can lead to serious complications in unvaccinated infants.

In the UK, children receive a primary course of pertussis vaccinations at two, three and four months of age, with a further preschool pertussis booster vaccination three years after completing the primary course.

Evidence suggests that pertussis infection is rising in adolescents and adults, but an adolescent booster vaccination has so far not been introduced in the UK.

To help inform these discussions, a team of researchers led by Kay Wang at the University of Oxford set out to find whether pertussis is still an important cause of persistent cough among school age children even after the introduction of the preschool booster.

Between November 2010 and December 2012, they recruited 279 children aged five to 15 years who visited their family doctor with a persistent cough of two to eight weeks' duration. The doctors were in 22 general practices in the Thames Valley.

Evidence of recent pertussis infection was confirmed by laboratory testing of oral fluid and cough frequency was monitored over 24 hours using a wearable automated device in six children with confirmed infection.

A total of 56 (20%) children had evidence of recent pertussis infection, including 39 (18%) of 215 children who had been fully vaccinated.

The risk of pertussis was more than three times higher in children given the preschool pertussis booster vaccination more than seven years before visiting their doctor with persistent cough compared with those given the booster more recently.

The risk of pertussis was similar between children who received the five or three component preschool booster vaccine. Four of six children in whom cough frequency was measured coughed more than 400 times in 24 hours.

"Pertussis can still be found in a fifth of school age children who present in primary care with persistent cough and can cause clinically significant cough in fully vaccinated children," say the authors. "These findings will help to inform consideration of the need for an adolescent pertussis booster vaccination in the UK," they conclude.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. K. Wang, N. K. Fry, H. Campbell, G. Amirthalingam, T. G. Harrison, D. Mant, A. Harnden. Whooping cough in school age children presenting with persistent cough in UK primary care after introduction of the preschool pertussis booster vaccination: prospective cohort study. BMJ, 2014; 348 (jun24 18): g3668 DOI: 10.1136/bmj.g3668

Cite This Page:

BMJ-British Medical Journal. "A fifth of children visiting their doctor with a persistent cough could have whooping cough." ScienceDaily. ScienceDaily, 24 June 2014. <www.sciencedaily.com/releases/2014/06/140624220025.htm>.
BMJ-British Medical Journal. (2014, June 24). A fifth of children visiting their doctor with a persistent cough could have whooping cough. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2014/06/140624220025.htm
BMJ-British Medical Journal. "A fifth of children visiting their doctor with a persistent cough could have whooping cough." ScienceDaily. www.sciencedaily.com/releases/2014/06/140624220025.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins