Featured Research

from universities, journals, and other organizations

Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music

Date:
June 25, 2014
Source:
Universidad Politécnica de Madrid
Summary:
Scientists have analyzed morphological features extracted from dendritic spines of brain neurons to detect patterns in their distribution. Then a software tool was developed in order to convert these features into musical notes. This new technique will be able to explore new hypothesis to understand how human brain works and also search for new solutions to fight against diseases such as Alzheimer's, epilepsy and Parkinson's.

A sample of pyramidal dendrite.
Credit: Cajal Blue Brain project

New research conducted by the Cajal Blue Brain project was focused on the analysis of morphological features extracted from dendritic spines of brain neurons to detect patterns in their distribution. Software was developed in order to convert these features into musical notes. This new technique will be able to explore new hypothesis to understand how human brain works and also search for new solutions to fight against diseases such as Alzheimer's, epilepsy and Parkinson's.

Dendritic spines are key elements to understand cognition, memory and the synaptic organization of the cerebral cortex. This study is based on musical feedback for exploring dendritic spine morphology in pyramidal neurons to discover potential patterns in distributions of these structures. This is a hard task because of the irregular three-dimensional position of the spines, a high number of structures and also because of the dendritic shapes where the spines are found. In order to improve the analysis process of this data, the user can simultaneously explore the optical microscopy images along with symbolic visual data from images and musical sounds from the analyzed distributions. The musical exploration has allowed researchers to reveal some patterns which were completely hidden.

This new exploratory tool for the dendritic spine morphology can help neuroscientists with their studies on brain structure. This tool can be used as a complement of other conventional data techniques. In particular, the expert can search for patterns in the distribution of these types of spines from three-dimensional images obtained from an optical microscopy. In a similar way, the expert will be able to interactively analyze the morphological features found in digital images of these structures, such as composition, volume, length, surface, orientation, etc. All this would be possible by the guide of sounds generated from a software tool which is able to turn these features into music notes.

The possibilities of this tool can be tested on the AUDISPINE website. The version on this website does not aim to be an interactive application with full functionality. Researchers are working to develop an application that can be distributed internationally. The available version includes a selection of morphological features to analyze and some interactive performances such as fixing the position of the analysis of the two available views (imaging and music); selecting the dendrite interest region and playing music at different speeds.


Story Source:

The above story is based on materials provided by Universidad Politécnica de Madrid. Note: Materials may be edited for content and length.


Journal Reference:

  1. Pablo Toharia, Juan Morales, Octavio de Juan, Isabel Fernaud, Angel Rodríguez, Javier DeFelipe. Musical Representation of Dendritic Spine Distribution: A New Exploratory Tool. Neuroinformatics, 2014; 12 (2): 341 DOI: 10.1007/s12021-013-9195-0

Cite This Page:

Universidad Politécnica de Madrid. "Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music." ScienceDaily. ScienceDaily, 25 June 2014. <www.sciencedaily.com/releases/2014/06/140625101447.htm>.
Universidad Politécnica de Madrid. (2014, June 25). Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2014/06/140625101447.htm
Universidad Politécnica de Madrid. "Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music." ScienceDaily. www.sciencedaily.com/releases/2014/06/140625101447.htm (accessed September 1, 2014).

Share This




More Mind & Brain News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Coffee Then Napping: The (New) Key To Alertness

Coffee Then Napping: The (New) Key To Alertness

Newsy (Aug. 30, 2014) — Researchers say having a cup of coffee then taking a nap is more effective than a nap or coffee alone. Video provided by Newsy
Powered by NewsLook.com
Young Entrepreneurs Get $100,000, If They Quit School

Young Entrepreneurs Get $100,000, If They Quit School

AFP (Aug. 29, 2014) — Twenty college-age students are getting 100,000 dollars from a Silicon Valley leader and a chance to live in San Francisco in order to work on the start-up project of their dreams, but they have to quit school first. Duration: 02:20 Video provided by AFP
Powered by NewsLook.com
Baby Babbling Might Lead To Faster Language Development

Baby Babbling Might Lead To Faster Language Development

Newsy (Aug. 29, 2014) — A new study suggests babies develop language skills more quickly if their parents imitate the babies' sounds and expressions and talk to them often. Video provided by Newsy
Powered by NewsLook.com
Electrical Stimulation Boosts Brain Function, Study Says

Electrical Stimulation Boosts Brain Function, Study Says

Newsy (Aug. 29, 2014) — Researchers found an improvement in memory and learning function in subjects who received electric pulses to their brains. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins