Featured Research

from universities, journals, and other organizations

Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music

Date:
June 25, 2014
Source:
Universidad Politécnica de Madrid
Summary:
Scientists have analyzed morphological features extracted from dendritic spines of brain neurons to detect patterns in their distribution. Then a software tool was developed in order to convert these features into musical notes. This new technique will be able to explore new hypothesis to understand how human brain works and also search for new solutions to fight against diseases such as Alzheimer's, epilepsy and Parkinson's.

A sample of pyramidal dendrite.
Credit: Cajal Blue Brain project

New research conducted by the Cajal Blue Brain project was focused on the analysis of morphological features extracted from dendritic spines of brain neurons to detect patterns in their distribution. Software was developed in order to convert these features into musical notes. This new technique will be able to explore new hypothesis to understand how human brain works and also search for new solutions to fight against diseases such as Alzheimer's, epilepsy and Parkinson's.

Related Articles


Dendritic spines are key elements to understand cognition, memory and the synaptic organization of the cerebral cortex. This study is based on musical feedback for exploring dendritic spine morphology in pyramidal neurons to discover potential patterns in distributions of these structures. This is a hard task because of the irregular three-dimensional position of the spines, a high number of structures and also because of the dendritic shapes where the spines are found. In order to improve the analysis process of this data, the user can simultaneously explore the optical microscopy images along with symbolic visual data from images and musical sounds from the analyzed distributions. The musical exploration has allowed researchers to reveal some patterns which were completely hidden.

This new exploratory tool for the dendritic spine morphology can help neuroscientists with their studies on brain structure. This tool can be used as a complement of other conventional data techniques. In particular, the expert can search for patterns in the distribution of these types of spines from three-dimensional images obtained from an optical microscopy. In a similar way, the expert will be able to interactively analyze the morphological features found in digital images of these structures, such as composition, volume, length, surface, orientation, etc. All this would be possible by the guide of sounds generated from a software tool which is able to turn these features into music notes.

The possibilities of this tool can be tested on the AUDISPINE website. The version on this website does not aim to be an interactive application with full functionality. Researchers are working to develop an application that can be distributed internationally. The available version includes a selection of morphological features to analyze and some interactive performances such as fixing the position of the analysis of the two available views (imaging and music); selecting the dendrite interest region and playing music at different speeds.


Story Source:

The above story is based on materials provided by Universidad Politécnica de Madrid. Note: Materials may be edited for content and length.


Journal Reference:

  1. Pablo Toharia, Juan Morales, Octavio de Juan, Isabel Fernaud, Angel Rodríguez, Javier DeFelipe. Musical Representation of Dendritic Spine Distribution: A New Exploratory Tool. Neuroinformatics, 2014; 12 (2): 341 DOI: 10.1007/s12021-013-9195-0

Cite This Page:

Universidad Politécnica de Madrid. "Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music." ScienceDaily. ScienceDaily, 25 June 2014. <www.sciencedaily.com/releases/2014/06/140625101447.htm>.
Universidad Politécnica de Madrid. (2014, June 25). Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music. ScienceDaily. Retrieved November 20, 2014 from www.sciencedaily.com/releases/2014/06/140625101447.htm
Universidad Politécnica de Madrid. "Music can help neuroscience: Detecting patterns in neuronal dendrite spines by translating them into music." ScienceDaily. www.sciencedaily.com/releases/2014/06/140625101447.htm (accessed November 20, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Thursday, November 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids React to Lammily, The Realistic Barbie Alternative

Kids React to Lammily, The Realistic Barbie Alternative

Buzz60 (Nov. 19, 2014) — Artist Nickolay Lamm's Kickstarter-funded Lammily doll, based on his 'What Would Barbie Look Like as a Real Woman' project, is finally available to buy. Jen Markham explains how the doll's realistic proportions are going over with a test group of second-graders who are used to the impossible measurements of Barbie dolls. Video provided by Buzz60
Powered by NewsLook.com
Trans-Fat Foods Now Linked To Poor Memory

Trans-Fat Foods Now Linked To Poor Memory

Newsy (Nov. 19, 2014) — A study presented at the American Heart Association Scientific Sessions shows a link between diets high in trans fats and decreased memory recall. Video provided by Newsy
Powered by NewsLook.com
Creating Lifelong Love of Science and Math

Creating Lifelong Love of Science and Math

AP (Nov. 18, 2014) — Kelly Mathews is a new mom on a mission to get girls interested in science, technology, engineering and math, and it starts with her own daughter. The Girl Scouts are doing their part, too, by promoting S.T.E.M. through badges and activities. (Nov. 18) Video provided by AP
Powered by NewsLook.com
3D Fun Improves Child Therapy in Poland

3D Fun Improves Child Therapy in Poland

Reuters - Innovations Video Online (Nov. 17, 2014) — Scientists in Poland are helping children with autism and Down's Syndrome better focus on therapeutic exercises by taking them out of their real world environment and into a specially-designed 3D cave in which their imagination can flourish. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins