Featured Research

from universities, journals, and other organizations

Improved screening assay for buprenorphine in umbilical cord

Date:
July 1, 2014
Source:
United States Drug Testing Laboratories (USDTL)
Summary:
Researchers have improved umbilical cord screening assay for buprenorphine by reducing the positive result cutoff from 1.0 ng/g down to 0.5 ng/g. The improved umbilical cord buprenorphine assay gives the best possible detection of buprenorphine exposure, making it possible to identify more newborns exposed to buprenorphine in utero.

USDTL (United States Drug Testing Laboratory, Inc.) has succeeded in improving their umbilical cord screening assay for buprenorphine by reducing the positive result cutoff from 1.0 ng/g down to 0.5 ng/g. The improved umbilical cord buprenorphine assay gives the best possible detection of buprenorphine exposure, making it possible to identify more newborns exposed to buprenorphine in utero.

Buprenorphine Diversion: A Growing Problem

Buprenorphine is an opioid product used in the treatment of addiction to heroin, hydrocodone, and other opioid substances. Buprenorphine is able to bind to the addiction receptors normally affected by illicit opiate drugs, without the intense euphoric feeling from drugs such as heroin. Used by prescription in place of an addict's normal drug of choice, buprenorphine helps eliminate withdrawal symptoms that come with quitting illicit opiate substances.

The supply and distribution of buprenorphine to medical, pharmaceutical and treatment facilities has increased more than 100 times since 2003. Unfortunately, the diversion of buprenorphine for non-medical and illicit use has increased as well. In some areas, buprenorphine may be a cheaper alternative to heroin or prescription opiates. Addicts may use it to help bridge the gap until they can afford their next drug purchase. When a preferred drug is not available, addicts may turn to buprenorphine to tide them over and prevent withdrawal symptoms. Others may self-medicate with buprenorphine, hoping to quit their opiate addiction, but unable to afford the cost of a treatment facility.

In the latest statistics from the National Survey on Drug Use and Health, 5.9% of pregnant women admitted to use of an illicit substance during pregnancy. A study from the University of Michigan Health System found that opiate use during pregnancy, including buprenorphine, increased more than 370% between the years 2000 and 2009. Buprenorphine exposure in the womb, like other opiates, may cause newborns to experience low birth weight, respiratory distress, and neonatal abstinence syndrome (NAS). Babies experiencing NAS often require longer hospital stays following birth, and possible morphine administration to treat withdrawal symptoms.

States are required by the Child Abuse Prevention and Treatment Act to establish policies and procedures for reporting cases of newborns exposed to illegal substances to child protective services agencies, and to establish plans of safe care for these newborns. Forensic drug testing of newborn samples such as umbilical cord tissue is a tool for healthcare practitioners to identify prenatal substance exposure.


Story Source:

The above story is based on materials provided by United States Drug Testing Laboratories (USDTL). Note: Materials may be edited for content and length.


Journal Reference:

  1. Zev Schuman-Olivier, Mark Albanese, Sarah E. Nelson, Lolita Roland, Francyne Puopolo, Lauren Klinker, Howard J. Shaffer. Self-treatment: Illicit buprenorphine use by opioid-dependent treatment seekers. Journal of Substance Abuse Treatment, 2010; 39 (1): 41 DOI: 10.1016/j.jsat.2010.03.014

Cite This Page:

United States Drug Testing Laboratories (USDTL). "Improved screening assay for buprenorphine in umbilical cord." ScienceDaily. ScienceDaily, 1 July 2014. <www.sciencedaily.com/releases/2014/07/140701085052.htm>.
United States Drug Testing Laboratories (USDTL). (2014, July 1). Improved screening assay for buprenorphine in umbilical cord. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2014/07/140701085052.htm
United States Drug Testing Laboratories (USDTL). "Improved screening assay for buprenorphine in umbilical cord." ScienceDaily. www.sciencedaily.com/releases/2014/07/140701085052.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins