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Tremors, shuffling and confusion may not be Parkinson's but Lewy Body Dementia

Date:
July 7, 2014
Source:
Lewy Body Dementia Association
Summary:
The importance of an accurate Lewy body dementia diagnosis, which may have life-saving implications, have been highlighted by experts. Affecting more than 1.3 million Americans, Lewy body dementia (LBD) is the most misdiagnosed form of dementia and, following Alzheimer’s disease, is the second most common cause of progressive dementia. It is associated with abnormal protein deposits in the brain, called Lewy bodies, that affect thinking, movement, behavior and mood, and is difficult to diagnose.

Today, the Lewy Body Dementia Association (LBDA) highlights the importance of an accurate Lewy body dementia diagnosis, which may have life-saving implications. Affecting more than 1.3 million Americans, Lewy body dementia (LBD) is the most misdiagnosed form of dementia and, following Alzheimer's disease, is the second most common cause of progressive dementia. LBD is associated with abnormal protein deposits in the brain, called Lewy bodies, that affect thinking, movement, behavior and mood. It's difficult to diagnose LBD, because its early symptoms resemble those found in Alzheimer's and Parkinson's disease.

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"Recognizing LBD at its earliest stage is critical not only for an accurate diagnosis by the appropriate specialist, " says James B. Leverenz, M.D., Director of the Cleveland Lou Ruvo Center for Brain Health at the Cleveland Clinic, "but also because it is important for a patient with LBD to be managed by an expert familiar with dementia in general and LBD in particular." Leverenz adds, "A primary care physician with the best intentions may not be well informed, so it becomes the duty of the patient and caregiver to know about resources, such as the LBDA and the Alzheimer Association, for help when needed."

The Difference Between LBD and Parkinson's

According to Leverenz, the combination of the motor signs of Parkinson's disease (slowed mobility, stooped posture and tremor) and mental confusion, especially if the degree of confusion fluctuates day to day, should raise a red flag for suspicion of LBD. Furthermore, Leverenz says if those symptoms are accompanied or preceded by REM sleep behavior disorder ("acting out dreams," dream enactment, hitting bed partner, falling out of bed) and visual hallucinations (seeing people, animals, etc., that aren't truly there), then the diagnosis of LBD should be strongly considered.

Even when all symptoms of LBD are present, it is critical for the evaluating doctor to look for underlying, TREATABLE causes of dementia. A thorough assessment will include an inventory of daily medications (drugs can produce a "chemical" state of pseudodementia), CT or MRI scan of the brain, blood tests for thyroid function and vitamin deficiency and other causes of dementia that can be identified by routine study.

While the symptoms of LBD may be similar to Alzheimer's and Parkinson's disease, the treatment strategy is more challenging because fewer medications can be used safely. People with LBD have medication sensitivities, and an early and accurate diagnosis can protect them from receiving medications that can worsen their symptoms, cause severe side effects or trigger a potentially deadly reaction. Leverenz warns, "The avoidance of medications that can worsen the symptoms of LBD cannot be overemphasized. Every patient with LBD and their caregiver(s) should be familiar with the list of acceptable and forbidden ("contraindicated") drugs." Keeping a handy list of these medications can be very useful for medical appointments and other potential medical events, such as an emergency room visit. People with LBD and their caregivers should both carry LBDA's Medical Alert Wallet Card and present it to any new physicians or upon hospitalization. Physicians can learn more on the LBDA Website about emergency treatment of LBD-related psychosis.

LBD: A Debilitating Dementia

A debilitating disease, Lewy body dementia impairs thinking, movement, sleep and behavior (causing people to see hallucinations or act out dreams, sometimes violently). Also, it affects autonomic body functions, such as blood pressure control, temperature regulation, and digestion. Recognizing symptoms early can help people with LBD get comprehensive and appropriate treatment and help caregivers get much needed support.


Story Source:

The above story is based on materials provided by Lewy Body Dementia Association. Note: Materials may be edited for content and length.


Cite This Page:

Lewy Body Dementia Association. "Tremors, shuffling and confusion may not be Parkinson's but Lewy Body Dementia." ScienceDaily. ScienceDaily, 7 July 2014. <www.sciencedaily.com/releases/2014/07/140707212539.htm>.
Lewy Body Dementia Association. (2014, July 7). Tremors, shuffling and confusion may not be Parkinson's but Lewy Body Dementia. ScienceDaily. Retrieved November 22, 2014 from www.sciencedaily.com/releases/2014/07/140707212539.htm
Lewy Body Dementia Association. "Tremors, shuffling and confusion may not be Parkinson's but Lewy Body Dementia." ScienceDaily. www.sciencedaily.com/releases/2014/07/140707212539.htm (accessed November 22, 2014).

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