Featured Research

from universities, journals, and other organizations

Sunscreens do not fully protect against the development of melanoma, mouse study suggests

Date:
July 14, 2014
Source:
Asociación RUVID
Summary:
Sunscreen, even with a sun protection factor (SPF) 50, may not fully protect against the development of melanoma. Sunscreen protects against immediate radiation damage including sunburn, but the radiation can still penetrate and damage the DNA of cells and cause cancer, according to an animal study.

Berta López Sánchez-Laorden.
Credit: Image courtesy of Asociación RUVID

The researcher at the Neurosciences Institute, Joint Center of the University Miguel Hernández (UMH) in Elche and the Higher Council for Scientific Research (CSIC), Berta López Sánchez-Laorden co-authored a study that concluded that sunscreens do not protect totally against the development of skin cancer. The research was recently published in Nature.

The study demonstrates that sunscreen, even with a sun protection factor (SPF) 50, may not fully protect against the development of melanoma. According to the researcher at the UMH Berta López Sánchez-Laorden, sunscreen protects against immediate radiation damage including sunburn, but the radiation can still penetrate and damage the DNA of cells and cause cancer.

Through the use of genetically modified mice particularly susceptible to melanoma, the researcher discovered that ultraviolet light causes mutations in the DNA of melanocytes in a gene called p53. This is one of the genes considered as guardians of the genome as it is key in detecting and repairing damage that accumulates in cells, such as the produced by ultraviolet light, and is a major barrier of the body against cancer.

Several epidemiological studies have shown an association between sun exposure and the increased risk of melanoma. However, the molecular mechanism that causes this to happen was not clear.

Berta López Sánchez-Laorden is co-author of the work, which has been one of the main projects carried out during her first postdoctoral, developed in the Institute of Cancer Research in London and the Cancer Research UK Manchester Institute.


Story Source:

The above story is based on materials provided by Asociación RUVID. Note: Materials may be edited for content and length.


Journal Reference:

  1. Amaya Viros, Berta Sanchez-Laorden, Malin Pedersen, Simon J. Furney, Joel Rae, Kate Hogan, Sarah Ejiama, Maria Romina Girotti, Martin Cook, Nathalie Dhomen, Richard Marais. Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53. Nature, 2014; DOI: 10.1038/nature13298

Cite This Page:

Asociación RUVID. "Sunscreens do not fully protect against the development of melanoma, mouse study suggests." ScienceDaily. ScienceDaily, 14 July 2014. <www.sciencedaily.com/releases/2014/07/140714100342.htm>.
Asociación RUVID. (2014, July 14). Sunscreens do not fully protect against the development of melanoma, mouse study suggests. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2014/07/140714100342.htm
Asociación RUVID. "Sunscreens do not fully protect against the development of melanoma, mouse study suggests." ScienceDaily. www.sciencedaily.com/releases/2014/07/140714100342.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) — Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
West Africa Gripped by Deadly Ebola Outbreak

West Africa Gripped by Deadly Ebola Outbreak

AFP (July 28, 2014) — The worst-ever outbreak of the deadly Ebola epidemic grips west Africa, killing hundreds. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com
Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) — A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
Google's Next Frontier: The Human Body

Google's Next Frontier: The Human Body

Newsy (July 27, 2014) — Google is collecting genetic and molecular information to paint a picture of the perfectly healthy human. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins