Featured Research

from universities, journals, and other organizations

Sunscreens do not fully protect against the development of melanoma, mouse study suggests

Date:
July 14, 2014
Source:
Asociación RUVID
Summary:
Sunscreen, even with a sun protection factor (SPF) 50, may not fully protect against the development of melanoma. Sunscreen protects against immediate radiation damage including sunburn, but the radiation can still penetrate and damage the DNA of cells and cause cancer, according to an animal study.

Berta López Sánchez-Laorden.
Credit: Image courtesy of Asociación RUVID

The researcher at the Neurosciences Institute, Joint Center of the University Miguel Hernández (UMH) in Elche and the Higher Council for Scientific Research (CSIC), Berta López Sánchez-Laorden co-authored a study that concluded that sunscreens do not protect totally against the development of skin cancer. The research was recently published in Nature.

Related Articles


The study demonstrates that sunscreen, even with a sun protection factor (SPF) 50, may not fully protect against the development of melanoma. According to the researcher at the UMH Berta López Sánchez-Laorden, sunscreen protects against immediate radiation damage including sunburn, but the radiation can still penetrate and damage the DNA of cells and cause cancer.

Through the use of genetically modified mice particularly susceptible to melanoma, the researcher discovered that ultraviolet light causes mutations in the DNA of melanocytes in a gene called p53. This is one of the genes considered as guardians of the genome as it is key in detecting and repairing damage that accumulates in cells, such as the produced by ultraviolet light, and is a major barrier of the body against cancer.

Several epidemiological studies have shown an association between sun exposure and the increased risk of melanoma. However, the molecular mechanism that causes this to happen was not clear.

Berta López Sánchez-Laorden is co-author of the work, which has been one of the main projects carried out during her first postdoctoral, developed in the Institute of Cancer Research in London and the Cancer Research UK Manchester Institute.


Story Source:

The above story is based on materials provided by Asociación RUVID. Note: Materials may be edited for content and length.


Journal Reference:

  1. Amaya Viros, Berta Sanchez-Laorden, Malin Pedersen, Simon J. Furney, Joel Rae, Kate Hogan, Sarah Ejiama, Maria Romina Girotti, Martin Cook, Nathalie Dhomen, Richard Marais. Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53. Nature, 2014; DOI: 10.1038/nature13298

Cite This Page:

Asociación RUVID. "Sunscreens do not fully protect against the development of melanoma, mouse study suggests." ScienceDaily. ScienceDaily, 14 July 2014. <www.sciencedaily.com/releases/2014/07/140714100342.htm>.
Asociación RUVID. (2014, July 14). Sunscreens do not fully protect against the development of melanoma, mouse study suggests. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2014/07/140714100342.htm
Asociación RUVID. "Sunscreens do not fully protect against the development of melanoma, mouse study suggests." ScienceDaily. www.sciencedaily.com/releases/2014/07/140714100342.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) — An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins