Featured Research

from universities, journals, and other organizations

Cases of drug-resistant superbug significantly rise in southeastern U.S.

Date:
July 16, 2014
Source:
Society for Healthcare Epidemiology of America
Summary:
Cases of the highly contagious, drug-resistant bacteria, carbapenem-resistant Enterobacteriaceae, have increased fivefold in community hospitals in the Southeastern United States, according to a new study. CRE are a class of highly antibiotic-resistant bacteria that are not susceptible to most commonly-used antibiotics. Labeled "one of the three greatest threats to human health" by the World Health Organization, these dangerous pathogens can cause infections in the urinary tract, lungs, blood, and other areas.

Cases of the highly contagious, drug-resistant bacteria, carbapenem-resistant Enterobacteriaceae (CRE), have increased fivefold in community hospitals in the Southeastern United States, according to a new study published in the August issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

Related Articles


"This dangerous bacteria is finding its way into healthcare facilities nationwide. Even this marked increase likely underestimates the true scope of the problem given variations in hospital surveillance practices," said Joshua Thaden, MD, a lead author of the study. "A CRE epidemic is fast approaching. We must take immediate and significant action in order to limit the transmission of these dangerous pathogens throughout our hospitals and acute care facilities."

CRE are a class of highly antibiotic-resistant bacteria that are not susceptible to most commonly-used antibiotics. Labeled "one of the three greatest threats to human health" by the World Health Organization, these dangerous pathogens can cause infections in the urinary tract, lungs, blood, and other areas. Patients with CRE infections have high risk of mortality, with at least 48 percent of cases proving fatal.

Over the five-year study period, researchers identified 305 unique patients with CRE through the Duke Infection Control Outreach Network (DICON), a cluster of 25 community hospitals in the Southeastern U.S. In this retrospective cohort, infection prevention professionals identified cases via prospective surveillance using standardized protocols in all hospitals. However, the majority of microbiology laboratories in the study had not adopted the most recent, and more sensitive, guidelines for detecting the bacteria. In hospitals that had adopted the guidelines, the rate of CRE detection was more than three times higher.

Half of the patients with CRE were symptomatic (59 percent) and nearly all cases were healthcare-associated (60 percent community-onset, healthcare-associated, 34 percent hospital onset). The higher rate of infection was found to stem from a combination of factors, including:

  • Increased use of broad-spectrum antibiotics;
  • Ease of which CRE enzymes could be transmitted among bacteria; and
  • Increased transmission between long-term acute care facilities and community hospitals.

"This is a wake up call for community hospitals. More must be done to prepare and respond to CRE, specifically infection control to limit person-to-person transmission and improved laboratory detection," said Thaden.

In a commentary accompanying the study, Christopher Pfeiffer, MD, noted increased financial and staffing shortages as two challenges community hospitals faced in trying to prevent transmission of the superbug. Pfeiffer offered, "CRE prevention and control could benefit from regional collaborative networks armed with knowledge and resources to assist individual facilities and coordinate between facilities, which have been successful in the control of other antibiotic-resistant bacteria."

In 2012, the Centers for Disease Control and Prevention developed a CRE toolkit to help protect patients and prevent transmission.The toolkit is available at http://www.cdc.gov/hai/organisms/cre/cre-toolkit.


Story Source:

The above story is based on materials provided by Society for Healthcare Epidemiology of America. Note: Materials may be edited for content and length.


Journal Reference:

  1. Joshua T. Thaden, Sarah S. Lewis, Kevin C. Hazen, Kirk Huslage, Vance G. Fowler, Rebekah W. Moehring, Luke F. Chen, Constance D. Jones, Zack S. Moore, Daniel J. Sexton, Deverick J. Anderson. Rising Rates of Carbapenem-Resistant Enterobacteriaceae in Community Hospitals: A Mixed-Methods Review of Epidemiology and Microbiology Practices in a Network of Community Hospitals in the Southeastern United States. Infection Control and Hospital Epidemiology, 2014; 35 (8): 978 DOI: 10.1086/677157

Cite This Page:

Society for Healthcare Epidemiology of America. "Cases of drug-resistant superbug significantly rise in southeastern U.S.." ScienceDaily. ScienceDaily, 16 July 2014. <www.sciencedaily.com/releases/2014/07/140716123837.htm>.
Society for Healthcare Epidemiology of America. (2014, July 16). Cases of drug-resistant superbug significantly rise in southeastern U.S.. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2014/07/140716123837.htm
Society for Healthcare Epidemiology of America. "Cases of drug-resistant superbug significantly rise in southeastern U.S.." ScienceDaily. www.sciencedaily.com/releases/2014/07/140716123837.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins