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Lung cancer diagnosis tool shown to be safe and effective for older patients

Date:
August 4, 2014
Source:
Manchester University
Summary:
A procedure to take tissue samples from lung cancer patients can be used safely in the elderly – allowing doctors to make a more accurate diagnosis and to choose appropriate treatment, a recent study has found. Half of all lung cancer patients are over 70 years old when first diagnosed, but studies have shown that these older patients are less likely to receive an accurate diagnosis. A correct assessment of the stage of a patient’s disease – how much their tumor has grown and spread – is key to ensuring they receive the right treatment.

A recent study in Manchester has found that a procedure to take tissue samples from lung cancer patients can be used safely in the elderly -- allowing doctors to make a more accurate diagnosis and to choose appropriate treatment.

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Half of all lung cancer patients are over 70 years old when first diagnosed, but studies have shown that these older patients are less likely to receive an accurate diagnosis.

A correct assessment of the stage of a patient's disease -- how much their tumor has grown and spread -- is key to ensuring they receive the right treatment.

Non-invasive methods of checking whether a patient's cancer has spread to their lymph nodes have limited sensitivity and until recently the only way to obtain a tissue sample was under general anaesthetic -- limiting its use in elderly patients who often present with other conditions that may restrict the use of general anaesthesia.

Now researchers at University Hospital of South Manchester NHS Foundation Trust and The University of Manchester -- part of the Manchester Cancer Research Centre -- have looked at a newer technique: endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). This method is carried out under sedation while the patient is still conscious and uses ultrasound to guide a sampling needle down and through the airways of the lungs.

Dr Richard Booton, Consultant Respiratory Physician at the North West Lung Centre and senior lecturer at the University's Institute of Inflammation and Repair who led the study, said: "We wanted to see if there were any differences between patients aged less than 70 years old and those older than 70, in terms of both the safety of the technique and how useful it was for diagnosis.

"The team recently published their results in the Journal of Thoracic Oncology and found that the procedure was well tolerated at all ages -- even in those patients aged over 80 years old. They also showed that EBUS-TBNA is effective for assessing whether a patient's tumor had spread to the lymph nodes.

"Being able to safely take tissue samples will also allow us to test for specific tumor sub-types and better decide the most appropriate treatment for each individual patient," added Dr Booton.


Story Source:

The above story is based on materials provided by Manchester University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Matthew Evison, Philip A. J. Crosbie, Julie Martin, Paul Bishop, Helen Doran, Leena Joseph, Anshuman Chaturvedi, Philip V. Barber, Richard Booton. EBUS-TBNA in Elderly Patients with Lung Cancer. Journal of Thoracic Oncology, 2014; 9 (3): 370 DOI: 10.1097/JTO.0000000000000085

Cite This Page:

Manchester University. "Lung cancer diagnosis tool shown to be safe and effective for older patients." ScienceDaily. ScienceDaily, 4 August 2014. <www.sciencedaily.com/releases/2014/08/140804065948.htm>.
Manchester University. (2014, August 4). Lung cancer diagnosis tool shown to be safe and effective for older patients. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2014/08/140804065948.htm
Manchester University. "Lung cancer diagnosis tool shown to be safe and effective for older patients." ScienceDaily. www.sciencedaily.com/releases/2014/08/140804065948.htm (accessed October 31, 2014).

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