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Polypill strategy to improve global secondary cardiovascular prevention

Date:
August 4, 2014
Source:
American College of Cardiology
Summary:
The polypill, a combination pill taken just once a day that includes key medications for secondary prevention of heart disease, may be an effective low-cost strategy to improve adherence to medication recommendations and reduce costs, researchers report.

This Central Illustration for the article shows adherence to the polypill compared to usual care with multiple pills extracted from published research studies, and identifies reasons patients fail to take medications prescribed for secondary prevention of heart disease.
Credit: Journal of the American College of Cardiology J Am Coll Cardiol. 2014;64(6):613-621

The polypill, a combination pill taken just once a day that includes key medications for secondary prevention of heart disease, may be an effective low-cost strategy to improve adherence to medication recommendations and reduce costs, according to researchers from Spain and New York, who reviewed research on the polypill.

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The review article, "A Polypill Strategy to Improve Global Secondary Cardiovascular Prevention," was published online in the Journal of the American College of Cardiology and will appear in the August 12, 2014 print issue.

Cardiovascular disease is the leading global cause of death, accounting for 17.3 million deaths per year. As the population ages and patients with heart disease survive longer, a growing pool of patients could benefit from secondary prevention of heart disease.

Secondary prevention includes lifestyle changes and the use of medications -- including statins, medications to reduce blood pressure, and antithrombotic agents. Use of these medications, which are generally low cost and safe, is thought to be responsible for half of the overall 50 percent reduction in mortality from heart disease in the past 20 years in some Western countries.

According to the researchers, there is room for improvement in secondary prevention, especially in nations with limited resources. The polypill, a combination pill taken just once a day that includes key medications for secondary prevention of heart disease, has been proposed as a low-cost strategy to improve adherence and reduce costs.


Story Source:

The above story is based on materials provided by American College of Cardiology. Note: Materials may be edited for content and length.


Journal Reference:

  1. José M. Castellano, Ginés Sanz, Antonio Fernandez Ortiz, Ester Garrido, Sameer Bansilal, Valentin Fuster. A Polypill Strategy to Improve Global Secondary Cardiovascular Prevention. Journal of the American College of Cardiology, 2014; 64 (6): 613 DOI: 10.1016/j.jacc.2014.06.009

Cite This Page:

American College of Cardiology. "Polypill strategy to improve global secondary cardiovascular prevention." ScienceDaily. ScienceDaily, 4 August 2014. <www.sciencedaily.com/releases/2014/08/140804171353.htm>.
American College of Cardiology. (2014, August 4). Polypill strategy to improve global secondary cardiovascular prevention. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2014/08/140804171353.htm
American College of Cardiology. "Polypill strategy to improve global secondary cardiovascular prevention." ScienceDaily. www.sciencedaily.com/releases/2014/08/140804171353.htm (accessed October 26, 2014).

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