Featured Research

from universities, journals, and other organizations

No apparent link between sleep apnea and cancer: Large study

Date:
August 5, 2014
Source:
Canadian Medical Association Journal
Summary:
There appears to be no link between obstructive sleep apnea and cancer development, according to a large study. Several previous studies have shown an association, although they have been small and contain measurement biases. "We were not able to confirm previous hypotheses that obstructive sleep apnea is a cause of overall cancer development through intermittent hypoxemia," write the authors. "However, in subgroup analyses, we found that the level of oxygen desaturation was associated with the development of smoking-related cancer."

Obstructive sleep apnea, in which people stop breathing for short periods while sleeping, affects about 5% of Canadian adults aged 45 years or older and can negatively affect health. More than 1 in 5 adult Canadians have risk factors for sleep apnea such as being overweight, being male and having diabetes, chronic nasal congestion or other health conditions.

Related Articles


Studies have postulated that obstructive sleep apnea may be linked to cancer because of low levels of oxygen in the blood.

"There is a need for a sufficiently large cohort study with a long enough follow-up to allow for the potential development of cancer that adjusts for important potential confounders, examines common cancer subtypes and has a rigorous assessment of both obstructive sleep apnea and cancer," writes Dr. Tetyana Kendzerska, Institute for Clinical Evaluative Sciences (ICES) and Women's College Hospital, University of Toronto, Toronto, Ont., with coauthors.

To understand whether obstructive sleep apnea is associated with cancer development, researchers undertook a study of 10 149 patients with the disorder who underwent a sleep study between 1994 and 2010. They linked this information to health administrative databases from 1991 to 2013. At the start of the study, 520 (5.1%) had a cancer diagnosis. In the study follow-up period (median 7.8 years), 627 (6.5%) people who did not have cancer at baseline had incident cancer. Prostate, breast, colorectal and lung cancers were the most common.

After controlling for cancer risk factors, the researchers found no apparent causal link between obstructive sleep apnea and cancer.

"We were not able to confirm previous hypotheses that obstructive sleep apnea is a cause of overall cancer development through intermittent hypoxemia [low blood oxygen levels]," write the authors. "However, in subgroup analyses, we found that the level of oxygen desaturation was associated with the development of smoking-related cancer."


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. Kendzerska, R. S. Leung, G. Hawker, G. Tomlinson, A. S. Gershon. Obstructive sleep apnea and the prevalence and incidence of cancer. Canadian Medical Association Journal, 2014; DOI: 10.1503/cmaj.140238

Cite This Page:

Canadian Medical Association Journal. "No apparent link between sleep apnea and cancer: Large study." ScienceDaily. ScienceDaily, 5 August 2014. <www.sciencedaily.com/releases/2014/08/140805132001.htm>.
Canadian Medical Association Journal. (2014, August 5). No apparent link between sleep apnea and cancer: Large study. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2014/08/140805132001.htm
Canadian Medical Association Journal. "No apparent link between sleep apnea and cancer: Large study." ScienceDaily. www.sciencedaily.com/releases/2014/08/140805132001.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins