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Licorice manufacturers encouraged to state daily limit of consumption

Date:
March 2, 2015
Source:
Elsevier
Summary:
A recent case study details the account of a 10-year-old boy who suffered seizures after over-indulging in licorice sweets. The boy was admitted to hospital in Bologna, Italy after suffering a 2 minute tonic-clonic seizure. A cluster of another three generalized seizures occurred in the next few hours. The boy also complained of a bad headache and had high blood pressure. Doctors discovered that he had been eating at least 20 licorice sweets each day for the past four months. This resulted in the consumption of 2.88 mg/kg of glycyrrhizic acid (one of the active ingredients of licorice), well above the World Health Organization's recommended maximum of 2 mg/kg.
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A recent case study published in Pediatric Neurology details the account of a 10-year-old boy who suffered seizures after over-indulging in licorice sweets.

A 10-year-old boy was admitted to hospital in Bologna, Italy after suffering a 2 minute tonic-clonic seizure. Dr Davide Tassinari and colleagues from the University of Bologna, Italy reported that a cluster of another three generalized seizures occurred in the next few hours. The boy also complained of a bad headache and had high blood pressure. Investigations were conducted using cranial computed tomography (CT) and magnetic resonance imaging (MRI), to investigate the possibility of posterior reversible encephalopathy syndrome (PRES). However, the major clinical conditions that lead to PRES were all ruled out.

During a medical examination a week later doctors noticed that the boy's teeth were black. It transpired that he had been eating at least 20 licorice sweets each day for the past four months. This resulted in the consumption of 2.88 mg/kg of glycyrrhizic acid (one of the active ingredients of licorice), well above the World Health Organization's recommended maximum of 2 mg/kg. This excessive consumption had resulted in his development of hypertension (or high blood pressure), and in turn PRES. After the boy stopped eating the sweets, his anti-hypertensive treatment was gradually reduced and his blood pressure returned to normal.

The authors note that the risk is particularly high for children with a low body weight. They recommend that licorice sweet manufacturers should state a recommended daily amount as a safety measure.


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Materials provided by Elsevier. Note: Content may be edited for style and length.


Journal Reference:

  1. Davide Tassinari, Rosalba Bergamaschi, Ilaria Corsini, Susanna Landini, Benedetta Romanin, Elisa Ballarini, Fabrizio De Ponti, Filomena Carfagnini, Francesco Toni, Filippo Bernardi. Posterior Reversible Encephalopathy Syndrome Associated with Licorice Consumption: A Case Report in a 10-Year-Old Boy. Pediatric Neurology, 2014; DOI: 10.1016/j.pediatrneurol.2014.12.001

Cite This Page:

Elsevier. "Licorice manufacturers encouraged to state daily limit of consumption." ScienceDaily. ScienceDaily, 2 March 2015. <www.sciencedaily.com/releases/2015/03/150302081147.htm>.
Elsevier. (2015, March 2). Licorice manufacturers encouraged to state daily limit of consumption. ScienceDaily. Retrieved May 24, 2017 from www.sciencedaily.com/releases/2015/03/150302081147.htm
Elsevier. "Licorice manufacturers encouraged to state daily limit of consumption." ScienceDaily. www.sciencedaily.com/releases/2015/03/150302081147.htm (accessed May 24, 2017).

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