Cancer News
August 27, 2016

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August 27, 2016

Aug. 26, 2016 — Researchers have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a ... read more

Discovery of a Novel Wnt Inhibitor With Potential to Eradicate Colorectal Cancer Stem Cells, Report Researchers

Aug. 26, 2016 — A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. The inhibitor may provide a ... read more

Targeting Low-Oxygen Patches Inside Lung Cancer Tumors Could Help Prevent Drug Resistance

Aug. 25, 2016 — With the right treatment schedule, medications known as hypoxia-activated prodrugs (HAPs) could help prevent drug resistance in a subtype of lung cancer, according to a ... read more

Immune System Infighting Explains Pancreatic Cancer's Aggression

Aug. 25, 2016 — Conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer, report researchers. Curbing this infighting has the potential to make treatment more ... read more

Study Examines Financial Conflict of Interests Among NCCN Guideline Authors

Aug. 25, 2016 — A new study quantifies industry financial conflicts of interest (FCOIs) among authors of National Comprehensive Cancer Network (NCCN) guidelines, work that influences practice and defines drugs ... read more

Researchers Question Process for Reviewing Coverage of 'Off Label' Cancer Drug Use

Aug. 25, 2016 — Physician-researchers have raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which ... read more

Aug. 25, 2016 — New research has shown how a cell surface molecule, Lymphotoxin ? receptor, controls entry of T-cells into the thymus, and as such presents an opportunity to understanding why cancer patients who ... read more

Fateful Evolution: New Study Improves Accuracy of Cancer Diagnosis

Aug. 25, 2016 — Researchers use evolutionary theory to make predictions about which Barrett's esophagus (BE) patients will go on to develop cancer. The results point the way toward more accurate medical ... read more

Smokers With Newly Discovered Genetic Markers Have Higher Lung Cancer Risk

Aug. 25, 2016 — Researchers discovered new genetic markers associated with a fast rate of nicotine metabolism, which potentially leads smokers to smoke more, thereby, increasing their risk for lung ... read more

Scientists Track Metabolic Pathways to Find Drug Combination for Pancreatic Cancer

Aug. 24, 2016 — Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown ... read more

Lymph Node Stage May Have Clinical Significance Among NSCLC Patients With Stage IV M1a

Aug. 24, 2016 — Analysis of a large non-small cell lung cancer (NSCLC) patient cohort with stage IV M1a disease identified lymph node staging as having clinical significance and an impact on ... read more

Aug. 24, 2016 — A researcher has discovered a way to kill spreading breast cancer cells and her new technology has generated a licensing agreement that will accelerate the therapy's path to clinical trials. ... read more

Aug. 24, 2016 — Multidrug resistance (MDR) is the mechanism by which many cancers develop resistance to chemotherapy. Researchers have developed nanoparticles that simultaneously deliver chemotherapy drugs to tumors ... read more

New Study Provides Important Insight Into How Tumors Metastasize

Aug. 23, 2016 — The growth of cancerous tumors is affected by the transforming growth factor beta (TGF-beta) in the body’s cells; TGF-beta both suppresses and stimulates tumor development, but it has not been ... read more

Melatonin Boost a Key to Fighting Breast Cancer

Aug. 23, 2016 — Melatonin, a hormone produced in the human brain, appears to suppress the growth of breast cancer tumors. While treatments based on this new, key discovery are still years away, the results give ... read more

Use of Electric Power Morcellation for Hysterectomy Declines Following FDA Warning

Aug. 23, 2016 — Researchers examined trends in the route of hysterectomy (abdominal, minimally invasive, or vaginal), use of electric power morcellators (a procedure in which the uterus is fragmented into smaller ... read more

Nanofiber Scaffolds Demonstrate New Features in the Behavior of Stem and Cancer Cells

Aug. 23, 2016 — A discovery in the field of biomaterials may open new frontiers in stem and cancer cell manipulation and associated advanced therapy development. Novel scaffolds are shown enabling cells to behave in ... read more

Aug. 23, 2016 — Researchers have designed a nanoparticle that mimics the bacterium Salmonella and may help to counteract a major mechanism of chemotherapy ... read more

Researchers Investigate Protein's Role in Cell Division

Aug. 23, 2016 — Scientists have taken a step toward translating the protein BubR1's function into a potential therapy for cancer. With this paper, authors begin the process of understanding how components of ... read more

Expecting the Worst Increases Side-Effects in Breast Cancer Patients on Hormone Therapies

Aug. 22, 2016 — A study of women receiving hormone therapies such as tamoxifen as part of their treatment for breast cancer has found that the number and seriousness of side effects they experienced were influenced ... read more

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