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Cluster headache
Cluster headaches are rare, extremely painful and debilitating headaches that occur in groups or clusters. Cluster headache sufferers typically experience severe headaches of a piercing quality near one eye or temple that last for fifteen minutes to three hours. The headaches are usually unilateral and occasionally change sides. Cluster headaches are classified as vascular headaches. The intense pain is caused by the dilation of blood vessels which creates pressure on the trigeminal nerve. While this process is the immediate cause of the pain, the etiology (underlying cause or causes) is not fully understood. Cluster headaches often go undiagnosed for many years, being confused with migraine or other causes of headache.
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Mind & Brain News
November 16, 2025
Nov. 15, 2025 Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This ...
Nov. 13, 2025 Researchers have uncovered surprising evidence that anxiety may be controlled not by neurons but by two dueling groups of immune cells inside the brain. These microglia act like biological pedals—one pushing anxiety forward and the other holding ...
Nov. 11, 2025 Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to ...
Nov. 10, 2025 Researchers identified SGK1 as a key chemical connecting childhood trauma to depression and suicidal behavior. High SGK1 levels were found in the brains of suicide victims and in people with genetic variants linked to early adversity. Drugs that ...
Nov. 9, 2025 Millions struggle with depression and anxiety, often enduring long waits for effective treatment. Scientists in Sweden, Denmark, and Germany are developing a genetic test to predict which medications will actually work. Using polygenic risk scores, ...
Nov. 8, 2025 Sertraline (Zoloft) may relieve emotional symptoms of depression and anxiety within two weeks, while physical side effects stabilize later. The research highlights how antidepressants can act on specific symptom networks rather than uniformly across ...
Nov. 8, 2025 Researchers have identified special immune cells in the brain that help slow Alzheimer’s. These microglia work to reduce inflammation and block the spread of harmful proteins. They appear to protect memory and brain health, offering a promising ...
Nov. 7, 2025 Prenatal exposure to the insecticide chlorpyrifos causes widespread brain abnormalities and poorer motor skills in children. Even after a residential ban, ongoing agricultural use continues to endanger developing ...
Nov. 6, 2025 Miniature antibodies from camels and llamas can slip into the brain more easily than conventional drugs, offering a new way to treat disorders like Alzheimer’s and schizophrenia. Researchers say these “nanobodies” could reshape the future of ...
Nov. 6, 2025 Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the condition as adults. The effect could stem from the ...
Nov. 6, 2025 Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...
Nov. 5, 2025 Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory ...
Latest Headlines
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Nov. 16, 2025 Chimps may revise their beliefs in surprisingly human-like ways. Experiments showed they switched choices when presented with stronger clues, demonstrating flexible reasoning. Computational modeling ...
Nov. 15, 2025 Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed ...
Nov. 11, 2025 Researchers scanning soccer fans’ brains found that wins trigger bursts of reward activity while losses dampen control signals. The results show how loyalty and rivalry can override logic, turning ...
Nov. 8, 2025 New research shows that the superior colliculus, a primitive brain region, can independently interpret visual information. This challenges long-held beliefs that only the cortex handles such complex ...
Nov. 5, 2025 Meditation is widely praised for its mental health benefits, but new research shows that it can also produce unexpected side effects for some people—from anxiety and dissociation to functional ...
Nov. 5, 2025 Scientists have shown that brain connectivity patterns can predict mental functions across the entire brain. Each region has a unique “connectivity fingerprint” tied to its role in cognition, ...
Nov. 4, 2025 Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of ...
Nov. 4, 2025 Researchers at MIT’s Picower Institute found that rotating waves of brain activity help restore focus after distractions. In animal tests, these rotations predicted performance: full rotations ...
Nov. 4, 2025 Researchers have discovered a specific set of neurons in the amygdala that can trigger anxiety and social deficits when overactive. By restoring the excitability balance in this brain region, they ...
Nov. 4, 2025 Using powerful 7-Tesla brain imaging, researchers mapped how the brainstem manages pain differently across the body. They discovered that distinct regions activate for facial versus limb pain, ...