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Skin cancers linked with reduced risk of Alzheimer's disease

Date:
April 19, 2018
Source:
Wiley
Summary:
Previous studies have demonstrated a decreased risk of Alzheimer's disease (AD) in individuals with various cancers, including non-melanoma skin cancers (including squamous cell cancers and basal cell cancers).
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Previous studies have demonstrated a decreased risk of Alzheimer's disease (AD) in individuals with various cancers, including non-melanoma skin cancers (including squamous cell cancers and basal cell cancers). A new Journal of the European Academy of Dermatology & Venereology study finds that this inverse relationship also holds true for malignant melanoma.

The study included patients aged 60-88 years with a clinic follow-up of at least 1 year and no diagnosis of AD or skin cancer at the beginning of the study. Of 1147 patients who were later diagnosed with malignant melanoma, 5 were diagnosed with subsequent AD. Of 2506 who were diagnosed with basal cell cancer, 5 had a subsequent AD diagnosis, and of 967 who were diagnosed with squamous cell cancer, only 1 had a subsequent AD diagnosis.

After adjustments, a diagnosis of malignant melanoma was associated with a 61% reduced risk of developing AD. For basal cell and squamous cell carcinomas, the reduced risks were 82% and 92%, respectively.


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Materials provided by Wiley. Note: Content may be edited for style and length.


Journal Reference:

  1. E. Ibler, G. Tran, K.A. Orrell, L. Serrano, S. Majewski, K.A. Sable, R. Thiede, A.E. Laumann, D.P. West, B. Nardone. Inverse association for diagnosis of Alzheimer's disease subsequent to both melanoma and non-melanoma skin cancers in a large, urban, single-centre, Midwestern US patient population. Journal of the European Academy of Dermatology and Venereology, 2018; DOI: 10.1111/jdv.14952

Cite This Page:

Wiley. "Skin cancers linked with reduced risk of Alzheimer's disease." ScienceDaily. ScienceDaily, 19 April 2018. <www.sciencedaily.com/releases/2018/04/180419100158.htm>.
Wiley. (2018, April 19). Skin cancers linked with reduced risk of Alzheimer's disease. ScienceDaily. Retrieved June 17, 2024 from www.sciencedaily.com/releases/2018/04/180419100158.htm
Wiley. "Skin cancers linked with reduced risk of Alzheimer's disease." ScienceDaily. www.sciencedaily.com/releases/2018/04/180419100158.htm (accessed June 17, 2024).

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