June 26, 2023 Scientists have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy ...
Mar. 30, 2023 White blood cells called neutrophils have an unappreciated role in eradicating solid tumors, according to a surprise ...
Feb. 16, 2023 Cancer immunotherapy involves using activated T cells to destroy tumors, but it doesn't work for all patients. Researchers have discovered that a kind of dendritic cell is crucial for ...
Jan. 23, 2023 Researchers have identified a relatively natural way to increase the numbers and antitumor activities of TILs. A team demonstrates how L-fucose, a nontoxic dietary plant sugar that is enriched in red ...
Jan. 9, 2023 New research has identified a protein that makes melanoma, the most serious type of skin cancer, more aggressive by giving cancer cells the ability to change the shape of their nucleus -- a ...
Jan. 9, 2023 Fewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. People taking vitamin D supplements regularly also had a considerably lower ...
Dec. 21, 2022 Researchers have used artificial DNA to target and kill cancer cells in a completely new way. The method was effective in lab tests against human cervical cancer- and breast cancer-derived cells, and ...
Dec. 16, 2022 A new study examined the combination of the common immunotherapy drug pembrolizumab (Keytruda) with all-trans retinoic acid (ATRA), a chemotherapy drug that targets myeloid-derived suppressor cells. ...
Dec. 7, 2022 A patient's own immune cells, multiplied into an army of billions of immune cells in a lab, can be used as a living medicine against metastatic melanoma, an aggressive form of skin cancer, as ...
Nov. 28, 2022 Researchers have identified a new method for scheduling radiation therapy that could be as much as 22 percent more effective at killing cancer cells than current standard radiation treatment ...
Oct. 31, 2022 Researchers have developed and validated a machine learning--based method to predict which patients with early-stage melanoma are most likely to experience a cancer ...
Oct. 31, 2022 A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery demonstrates ...
Sep. 28, 2022 A clinical trial showed a remarkable 20 percent advantage in the two-year overall survival rate for people with advanced melanoma who first received immunotherapy (72 percent survival rate) versus ...
Sep. 22, 2022 The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. ...
Sep. 20, 2022 Scientists have shown how tumor cells evade immunotherapy by generating unique, temporary cell-in-cell structures, where the inner cells remain in tact and can return to single tumor ...
Sep. 20, 2022 Researchers have deciphered a mechanism that enables skin cancer to metastasize to the brain and managed to delay the spread of the disease by 60% to 80% using existing ...
Sep. 19, 2022 Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research now provides ...
Sep. 19, 2022 Over the last decade, immune checkpoint blockers, or ICBs, have revolutionized treatment for various advanced cancers, including melanoma, the most aggressive skin cancer that was considered largely ...
Sep. 1, 2022 Researchers have shown that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. The findings could lead to a new class of drugs to selectively treat melanoma, ...
Aug. 23, 2022 Medical researchers report on their identification of high-risk patients with stage 3A disease and microscopic lymph node metastases who would benefit from adjuvant ...
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