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Methamphetamine

Methamphetamine (also referred to as methylamphetamine or desoxyephedrine) is a synthetic stimulant drug used for both medicinal and recreational purposes (the latter use is illegal in most countries). It is sometimes prescribed for ADHD and narcolepsy. It causes euphoria and excitement by acting directly on the brain's reward mechanisms, thus making it highly addictive. Methamphetamine rapidly enters the brain and causes a cascading release of norepinephrine and dopamine (and to a lesser extent, serotonin). Users may become obsessed or perform repetitive tasks such as cleaning, hand-washing or assembling and disassembling objects. Withdrawal is characterized by increased sleeping and eating, and depression-like symptoms, often accompanied by anxiety and drug-craving.

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Mind & Brain News

November 6, 2025

Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...
Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory ...
Meditation is widely praised for its mental health benefits, but new research shows that it can also produce unexpected side effects for some people—from anxiety and dissociation to functional impairment. Psychologist Nicholas Van Dam and his team ...
Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of harmful tau proteins in the brain. The researchers say ...
Researchers have discovered a specific set of neurons in the amygdala that can trigger anxiety and social deficits when overactive. By restoring the excitability balance in this brain region, they successfully reversed these symptoms in mice. The ...
Using powerful 7-Tesla brain imaging, researchers mapped how the brainstem manages pain differently across the body. They discovered that distinct regions activate for facial versus limb pain, showing the brain’s built-in precision pain control ...
Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides crucial insight for Parkinson’s treatment. Their ...
A team of scientists has developed a highly accurate blood test for Chronic Fatigue Syndrome. The test reads tiny DNA patterns that reveal the biological signature of the illness. For millions who’ve faced doubt and misdiagnosis, it’s a ...
Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of ...
Cognitive struggles are climbing across the U.S., especially among young and economically disadvantaged adults. Rates of self-reported cognitive disability nearly doubled in people under 40 between 2013 and 2023. Researchers suspect social and ...
Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced harmful tau buildup. The findings suggest that ...
People living in socially and economically disadvantaged neighborhoods may face higher dementia risks, according to new research from Wake Forest University. Scientists found biological signs of Alzheimer’s and vascular brain disease in those from ...

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