Pharmacology News
August 24, 2016

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updated 11:01pm EDT

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August 24, 2016

Conflicts Subverting Improved Health Conditions in Eastern Mediterranean Region

Aug. 24, 2016 — Improved health conditions and life expectancy over the past 20 years in the Eastern Mediterranean Region are being subverted by wars and civil unrest, according to a new scientific ... read more

We Are All 'Wired' for Addiction, Says Researcher

Aug. 24, 2016 — Drug addicts and non-addicts may have more in common than ever thought, according to a researcher who found that to some degree, everyone’s brain is “wired” to become ... read more

Aug. 24, 2016 — A protein often located on the surface of fat droplets within cells – and especially abundant in the muscles of endurance athletes – can kick-start the more efficient and healthful breakdown of ... read more

Scientists Track Metabolic Pathways to Find Drug Combination for Pancreatic Cancer

Aug. 24, 2016 — Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown ... read more

Study Shows Diabetes Treatment Helps Reduce Weight in Children With Autism

Aug. 24, 2016 — A drug that's been used for decades in the treatment of type 2 diabetes is proving effective in helping to control weight gain in children who are treated for autism spectrum disorder, according ... read more

Do the Tools to Quantify Addiction Help to Define It?

Aug. 24, 2016 — Understanding what counts as an addiction, and what can be done to address it is the work of researchers across many disciplines. But what tools are used to ‘measure’ addiction, and are these ... read more

Intravenous Glyburide Treatment May Reduce Dangerous Brain Swelling After Stroke

Aug. 23, 2016 — A phase 2 clinical trial of a drug that may alleviate brain swelling -- a dangerous stroke complication -- suggests the treatment may help reduce brain injury and death, and information from the ... read more

Mechanism That Alters Neural Excitability Offers Window Into Neuropsychiatric Disease

Aug. 23, 2016 — Researchers show, for the first time, that the well-known mechanism of gene expression control -- dynamic changes in DNA methylation -- is also involved in changes to the excitability of neural ... read more

Brief Rapamycin Therapy in Middle-Aged Mice Extends Lives

Aug. 23, 2016 — In mice, the drug rapamycin is known to extend lives and delay some age-related problems. Questions remain about about how it promotes healthy aging, when, how much and how long to administer ... read more

Recommended Blood Pressure Targets for Diabetes Are Being Challenged

Aug. 23, 2016 — The Swedish National Board of Health and Welfare recently raised the recommended target blood pressure for patients with diabetes. This may lead to more patients suffering from stroke or heart ... read more

Use of Electric Power Morcellation for Hysterectomy Declines Following FDA Warning

Aug. 23, 2016 — Researchers examined trends in the route of hysterectomy (abdominal, minimally invasive, or vaginal), use of electric power morcellators (a procedure in which the uterus is fragmented into smaller ... read more

Study Examines Reasons for High Cost of Prescriptions Drugs in US, Approaches to Reduce Costs

Aug. 23, 2016 — High prescription drug prices are attributable to several causes, including the approach the US has taken to granting government-protected monopolies to drug manufacturers, and the restriction of ... read more

New Zika Clone Could Be New Model for Developing Vaccine

Aug. 23, 2016 — Stopping the explosive spread of Zika virus -- which can lead to birth defects in babies born to infected mothers -- depends on genetic insights gleaned through new tools and models. Researchers ... read more

Study Uses Geo-Mapping to Identify 'Hot Spots' for Use of Fentanyl and Other Opiates

Aug. 23, 2016 — As the US experiences sharp increases in drug overdoses, researchers are using geo-mapping to look at the state, neighborhood by neighborhood, to identify 'hot spots' where the use of ... read more

Fall in UK Cardiovascular Disease Toll Not Equal Among All Four Countries or Genders

Aug. 22, 2016 — UK deaths from heart disease and stroke have plummeted by almost 70 percent over the past 30 years, but these improvements have not been equally distributed among all four countries, or between men ... read more

New Drug Target Could Prevent Tolerance, Addiction to Opioids, Study Finds

Aug. 22, 2016 — Researchers have identified a brain mechanism that could be a drug target to help prevent tolerance and addiction to opioid pain medication, such as ... read more

How Melanoma Spreads to Other Organs in the Body

Aug. 22, 2016 — In a landmark discovery, researchers have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. Their work may lead to a cure for the deadly ... read more

Rx Associated With Fracture Risk Infrequently Reduced After Fracture Occurrence

Aug. 22, 2016 — Is the occurrence of a fragility fracture -- where Medicare beneficiaries broke a hip, wrist or shoulder -- a missed opportunity to reduce exposure to prescription drugs associated with fracture ... read more

New Care Plan Improves Crohn’s Disease Complication Outcomes

Aug. 22, 2016 — The first published medical and surgical approach care plan for managing septic perianal Crohn’s disease, a serious complication that occurs in around 40 percent of Crohn’s disease patients has ... read more

Full Adherence to Guideline-Recommend Therapies Associated With Lower Rate of MACE

Aug. 22, 2016 — MINERVA results demonstrate full adherence to guideline-recommended therapies associated with lower rate of a second major cardiovascular event and cost ... read more

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