Pharmacology News
August 25, 2016

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August 25, 2016

Conflicts Subverting Improved Health Conditions in Eastern Mediterranean Region

Aug. 24, 2016 — Improved health conditions and life expectancy over the past 20 years in the Eastern Mediterranean Region are being subverted by wars and civil unrest, according to a new scientific ... read more

Scientists Track Metabolic Pathways to Find Drug Combination for Pancreatic Cancer

Aug. 24, 2016 — Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown ... read more

Concussions and Brain Injury: Can Omega-3 Intake Aid in Brain Health Recovery?

Aug. 24, 2016 — The treatment of concussions and traumatic brain injury (TBI) is a clinical challenge. Clinical studies thus far have failed to identify an effective treatment strategy when a combination of targets ... read more

Calcium Channel Blockers Caught in the Act at Atomic Level

Aug. 24, 2016 — Atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects by acting at different sites on the ... read more

How Do Antidepressants Trigger Fear and Anxiety?

Aug. 24, 2016 — Scientists have mapped out a serotonin-driven anxiety circuit that may explain 'anxiety' side effect of antidepressants. More than 100 million people worldwide take selective serotonin ... read more

New Small Molecule Compounds Could Treat Ebola Virus Infection

Aug. 24, 2016 — Scientists have found Ebola's Achilles' heel: a new kind of chemical compound can block the protein Ebola uses to break out of cells and infect new cells. The compounds could potentially be ... read more

Do the Tools to Quantify Addiction Help to Define It?

Aug. 24, 2016 — Understanding what counts as an addiction, and what can be done to address it is the work of researchers across many disciplines. But what tools are used to ‘measure’ addiction, and are these ... read more

Mechanism That Alters Neural Excitability Offers Window Into Neuropsychiatric Disease

Aug. 23, 2016 — Researchers show, for the first time, that the well-known mechanism of gene expression control -- dynamic changes in DNA methylation -- is also involved in changes to the excitability of neural ... read more

Recommended Blood Pressure Targets for Diabetes Are Being Challenged

Aug. 23, 2016 — The Swedish National Board of Health and Welfare recently raised the recommended target blood pressure for patients with diabetes. This may lead to more patients suffering from stroke or heart ... read more

New Zika Clone Could Be New Model for Developing Vaccine

Aug. 23, 2016 — Stopping the explosive spread of Zika virus -- which can lead to birth defects in babies born to infected mothers -- depends on genetic insights gleaned through new tools and models. Researchers ... read more

Medical Scientists Discover Potent Method for Improving Drug-Free Fertility Treatment

Aug. 23, 2016 — For those facing infertility, IVF has long been the established option to have a baby. Now medical scientists have discovered how to improve a woman's chances of becoming pregnant using a less ... read more

Aug. 23, 2016 — Researchers have designed a nanoparticle that mimics the bacterium Salmonella and may help to counteract a major mechanism of chemotherapy ... read more

Study Uses Geo-Mapping to Identify 'Hot Spots' for Use of Fentanyl and Other Opiates

Aug. 23, 2016 — As the US experiences sharp increases in drug overdoses, researchers are using geo-mapping to look at the state, neighborhood by neighborhood, to identify 'hot spots' where the use of ... read more

Fall in UK Cardiovascular Disease Toll Not Equal Among All Four Countries or Genders

Aug. 22, 2016 — UK deaths from heart disease and stroke have plummeted by almost 70 percent over the past 30 years, but these improvements have not been equally distributed among all four countries, or between men ... read more

New Drug Target Could Prevent Tolerance, Addiction to Opioids, Study Finds

Aug. 22, 2016 — Researchers have identified a brain mechanism that could be a drug target to help prevent tolerance and addiction to opioid pain medication, such as ... read more

How Melanoma Spreads to Other Organs in the Body

Aug. 22, 2016 — In a landmark discovery, researchers have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. Their work may lead to a cure for the deadly ... read more

After a Fracture, It's Time to Rethink Medications

Aug. 22, 2016 — Gerontologists underscore the importance of reviewing patients' prescription medications in the wake of a fracture. Appearing alongside original research that finds few changes are made to ... read more

Rx Associated With Fracture Risk Infrequently Reduced After Fracture Occurrence

Aug. 22, 2016 — Is the occurrence of a fragility fracture -- where Medicare beneficiaries broke a hip, wrist or shoulder -- a missed opportunity to reduce exposure to prescription drugs associated with fracture ... read more

New Care Plan Improves Crohn’s Disease Complication Outcomes

Aug. 22, 2016 — The first published medical and surgical approach care plan for managing septic perianal Crohn’s disease, a serious complication that occurs in around 40 percent of Crohn’s disease patients has ... read more

Full Adherence to Guideline-Recommend Therapies Associated With Lower Rate of MACE

Aug. 22, 2016 — MINERVA results demonstrate full adherence to guideline-recommended therapies associated with lower rate of a second major cardiovascular event and cost ... read more

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