Pharmacology News

November 12, 2025

Top Headlines

Scientists Find 15 Gut Bacteria That May Drive Heart Disease

Nov. 12, 2025 — Scientists in Seoul have uncovered 15 gut bacterial species linked to coronary artery disease, showing that microbes can influence heart health far beyond digestion. Their findings reveal how shifts in gut microbial function — including ...

Tiny Implant Wipes Out Bladder Cancer in 82% of Patients

Nov. 11, 2025 — TAR-200, a small drug-releasing implant, wiped out tumors in most patients with high-risk bladder cancer. Its slow, consistent release of chemotherapy proved far more effective than traditional short-term treatments. The therapy may replace bladder ...

AI Unravels the Hidden Communication of Gut Microbes

Nov. 10, 2025 — Scientists have turned to advanced AI to decode the intricate ecosystem of gut bacteria and their chemical signals. Using a Bayesian neural network called VBayesMM, researchers can now identify genuine biological links rather than random ...

New Online Tool Can Predict How Well Blood Pressure Drugs Will Work

Nov. 9, 2025 — A new blood pressure calculator built on extensive clinical trial data helps doctors accurately estimate how much each medication will reduce blood pressure. The tool simplifies complex treatment choices and replaces unreliable BP measurements with ...

Doctors Found a Way to Stop a Deadly Metformin Reaction

Nov. 9, 2025 — A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced deaths and sped up treatment times. Awareness also ...

A Simple DNA Test Could Reveal the Right Antidepressant for You

Nov. 9, 2025 — Millions struggle with depression and anxiety, often enduring long waits for effective treatment. Scientists in Sweden, Denmark, and Germany are developing a genetic test to predict which medications will actually work. Using polygenic risk scores, ...

DNA’s Hidden Power Could Transform How We Make Medicines

Nov. 8, 2025 — Scientists found that DNA’s phosphate groups can direct chemical reactions to make the correct mirror-image form of drug molecules. This breakthrough simplifies chiral drug production, reducing waste and energy use. Using a new “PS scanning” ...

Stanford Makes Stem Cell Transplants Safer Without Chemo

Nov. 7, 2025 — A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells without radiation, ...

Rare Desert Berry Could Transform Diabetes Treatment

Nov. 7, 2025 — An extract from a desert berry used in traditional Chinese medicine restored insulin function and stabilized metabolism in diabetic mice. The findings hint at a powerful natural alternative for holistic diabetes ...

Nanotech Makes Cancer Drug 20,000x Stronger, Without Side Effects

Nov. 5, 2025 — A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing power while avoiding side effects. This ...

Scientists Shocked to Find E. Coli Spreads as Fast as the Swine Flu

Nov. 4, 2025 — Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, scientists modeled bacterial transmission rates and ...

This New Drug Candidate Might Finally Outsmart Tuberculosis

Nov. 4, 2025 — A new compound called CMX410 may change the fight against tuberculosis. It targets a weak point in the bacteria’s defenses, even in drug-resistant forms of the disease. Created using a cutting-edge chemistry method, the drug shows promise for ...

Latest Headlines

updated 12:05pm EST

Wegovy in a Pill? Massive Weight Loss Results Revealed

Nov. 6, 2025 — Novo Nordisk’s oral semaglutide 25 mg achieved up to 16.6% weight loss in a landmark study, rivaling injectable Wegovy. The pill also improved cardiovascular risk factors and physical activity ...

Breakthrough Brain Discovery Reveals a Natural Way to Relieve Pain

Nov. 4, 2025 — Using powerful 7-Tesla brain imaging, researchers mapped how the brainstem manages pain differently across the body. They discovered that distinct regions activate for facial versus limb pain, ...

Think Melatonin Is Safe? New Research Reveals a Hidden Heart Risk

Nov. 4, 2025 — Long-term melatonin use for sleep problems may come with unexpected heart dangers. Researchers found that chronic users were almost twice as likely to die and 3.5 times more likely to be hospitalized ...

A 25-Year Crohn’s Disease Mystery Finally Cracked by AI

Nov. 3, 2025 — UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s ...

A Groundbreaking Brain Map Could Revolutionize Parkinson’s Treatment

Nov. 3, 2025 — Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides ...

Ancient Viruses Hidden Inside Bacteria Could Help Defeat Modern Infections

Nov. 3, 2025 — Penn State scientists uncovered an ancient bacterial defense where dormant viral DNA helps bacteria fight new viral threats. The enzyme PinQ flips bacterial genes to create protective proteins that ...

Ozempic and Wegovy Protect the Heart, Even Without Weight Loss

Oct. 31, 2025 — Semaglutide appears to safeguard the heart even when patients lose little weight. In a massive international trial, heart attack and stroke risk dropped by 20% regardless of BMI. The benefit seems ...

Electricity Reprograms Immune Cells to Speed Up Recovery

Oct. 30, 2025 — By electrically stimulating macrophages, scientists at Trinity College Dublin have found a way to calm inflammation and promote faster healing. The process turns these immune cells into ...

Scientists Find Hidden Antibiotic 100x Stronger Against Deadly Superbugs

Oct. 29, 2025 — A team of scientists discovered a hidden antibiotic 100 times stronger than existing drugs against deadly superbugs like MRSA. The molecule had been overlooked for decades in a familiar bacterium. It ...

How Strong Is Your Weed, Really? Scientists Say Labels Often Mislead

Oct. 23, 2025 — Colorado researchers discovered that nearly half of tested cannabis flower products exaggerated their THC levels, while concentrates were mostly accurate. The team’s statewide audit revealed ...

Scientists Reveal the Best Exercise to Ease Knee Arthritis Pain

Oct. 20, 2025 — A sweeping review of over 200 studies finds that aerobic exercises like walking and cycling offer the best pain relief and mobility gains for knee osteoarthritis. Compared to other types of exercise, ...

Can Ozempic Help You Cut Back on Alcohol? Researchers Think So

Oct. 18, 2025 — Semaglutide, tirzepatide, and other GLP-1 drugs appear to slow alcohol absorption and blunt its intoxicating effects, according to new research. The study found participants on these medications felt ...

C-Section Births Linked to Sleepless Nights and Painful Recoveries

Oct. 13, 2025 — Women who undergo C-sections are more likely to experience debilitating pain and sleep disorders in the months after giving birth. Researchers found both qualitative and large-scale data supporting ...

Fentanyl Overdoses Among Seniors Surge 9,000% — A Hidden Crisis Few Saw Coming

Oct. 13, 2025 — Overdose deaths from fentanyl mixed with stimulants have skyrocketed among seniors, increasing 9,000% in just eight years. Once thought to affect mainly the young, the opioid epidemic’s fourth wave ...

Breakthrough Cancer Therapy Stops Tumor Growth Without Harming Healthy Cells

Oct. 19, 2025 — Scientists have found a new way to stop cancer growth without damaging healthy cells. Researchers from the Francis Crick Institute and Vividion Therapeutics discovered a compound that blocks the ...

Exercise Might Be the Key to a Younger, Sharper Immune System

Oct. 14, 2025 — Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

MIT’s “stealth” Immune Cells Could Change Cancer Treatment Forever

Oct. 11, 2025 — MIT and Harvard scientists have designed an advanced type of immune cell called a CAR-NK cell that can destroy cancer while avoiding attack from the body’s own immune defenses. This innovation ...

Scientists Unlock Nature’s Secret to a Cancer-Fighting Molecule

Oct. 9, 2025 — Researchers have cracked the code behind how plants make mitraphylline, a rare cancer-fighting molecule. Their discovery of two critical enzymes explains how nature builds complex spiro-shaped ...

Scientists Discover Brain Circuit That Can Switch Off Chronic Pain

Oct. 10, 2025 — Scientists have pinpointed Y1 receptor neurons in the brain that can override chronic pain signals when survival instincts like hunger or fear take precedence. Acting like a neural switchboard, these ...

Two Common Drugs Could Reverse Fatty Liver Disease

Oct. 12, 2025 — Researchers at the University of Barcelona found that combining pemafibrate and telmisartan significantly reduces liver fat and cardiovascular risks in MASLD models. The drug duo works better ...

Brain Cancer That Eats the Skull Stuns Scientists

Oct. 5, 2025 — A new study shows glioblastoma isn’t confined to the brain—it erodes the skull and hijacks the immune system within skull marrow. The cancer opens channels that let inflammatory cells enter the ...

A Single Dose of Psilocybin May Rewire the Brain for Lasting Relief

Oct. 2, 2025 — Penn researchers found that psilocybin can calm brain circuits tied to pain and mood, easing both physical suffering and emotional distress in animal studies. The compound works in the anterior ...

Scientists Just Found a Molecule That Could Stop Parkinson’s in Its Tracks

Oct. 8, 2025 — Researchers have designed a peptide that prevents the deadly misfolding of alpha-synuclein, the protein behind Parkinson’s and some dementias. In lab and animal tests, it stabilized the protein and ...

Stunning Images Reveal How Antibiotics Shatter Bacterial Defenses

Sep. 29, 2025 — Researchers have revealed how polymyxins, crucial last-resort antibiotics, break down bacterial armor by forcing cells to overproduce and shed it. Astonishingly, the drugs only kill bacteria when ...

This European Treatment for Joint Pain Just Passed a Major Scientific Test

Oct. 15, 2025 — Korean researchers found that low-dose radiation therapy eased knee pain and improved movement in people with mild to moderate osteoarthritis. The treatment, far weaker than cancer radiation, showed ...

Oct. 13, 2025 — Finasteride, a common hair-loss drug, has long been tied to depression and suicide, but regulators ignored the warnings. Prof. Mayer Brezis’s review exposes global data showing psychiatric harm and ...

New Inhaler Halves Childhood Asthma Attacks

Sep. 28, 2025 — A groundbreaking international study has shown that a 2-in-1 budesonide-formoterol inhaler is far more effective than the standard salbutamol inhaler in children with mild asthma, cutting attacks by ...

Doctors Tested a Common Drug on COVID. The Results Are Stunning

Sep. 28, 2025 — Inhaled heparin significantly lowers the risk of death and ventilation in COVID-19 patients while also showing potential against other respiratory infections. With its unique triple-action benefits, ...

Scientists Uncover How to Block Pain Without Side Effects

Sep. 26, 2025 — Scientists have discovered a way to block pain while still allowing the body’s natural healing to take place. Current painkillers like ibuprofen and aspirin often come with harmful side effects ...

Scientists Finally Explain the Real Reason Pregnant Women Get Morning Sickness

Sep. 29, 2025 — Morning sickness isn’t just random misery—it’s a biological defense system shaped by evolution to protect the fetus. By linking immune responses to nausea and food aversions, UCLA researchers ...