Pharmacology News
August 31, 2016

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August 31, 2016

Bipolar Adolescents Continue to Have Elevated Substance Use Disorder Risk as Young Adults

Aug. 30, 2016 — A follow up to a previous study finding an association between adolescent bipolar disorder and the incidence of cigarette smoking and substance use disorder finds that risk was even greater five ... read more

Researchers Identify Multidrug-Resistant E. Coli Bacteria from New Jersey Patient

Aug. 30, 2016 — New Jersey researchers have identified what is believed to be the first strain of Escherichia coli bacteria from a patient in the United States that harbored two mobile genes making it resistant to ... read more

Antipsychotic Medications Linked to Increased Risk of Pneumonia in Persons With Alzheimer's Disease

Aug. 30, 2016 — Antipsychotic medications are associated with an increased risk of pneumonia in persons with Alzheimer's disease, according to new research. The risk of pneumonia was the highest at the ... read more

Swelling Obesity Rates May Be Tied to Childhood Antibiotic Use

Aug. 30, 2016 — As the nation's obesity rate continues to skyrocket, scientists across the country are combing the health records of 1.6 million kids to determine if childhood antibiotic use causes weight gain ... read more

A New Animal Model to Understand Metastasis in Sarcomas

Aug. 30, 2016 — Researchers have developed a modified version of an orthotopic model to recreate the metastatic steps in Ewing sarcoma, the second most common bone tumor in children and adolescents. This new model ... read more

System May Help Treat Rare Genetic Disorder, Reduce Severe Side Effects

Aug. 30, 2016 — Researchers have discovered a type of drug delivery system that may offer new hope for patients with a rare, ultimately fatal genetic disorder -- and make what might become a terrible choice a little ... read more

Molecular Switch May Sensitize Triple-Negative Breast Cancers to Immunotherapy

Aug. 29, 2016 — A new study offers compelling evidence that enzyme PRL-3 is 'switch' in TNF-R1 pathway, determining whether pathway helps cancer cells survive or die when challenged with ... read more

Aug. 29, 2016 — Researchers report their studies on the synthesis of a newly discovered 'game-changing' antibiotic, teixobactin in a new article. This underlies potential application and development of the ... read more

Doctors Prescribe Diabetes Treatment Medications 15 Times More Than Obesity Drugs

Aug. 29, 2016 — Obesity is a well-established major risk factor for developing diabetes, with almost 90% of people living with type 2 diabetes having obesity or overweight. Even with the close tie between obesity ... read more

Nebivolol Prevents Anthracycline-Induced Cardiotoxicity

Aug. 28, 2016 — Nebivolol prevents anthracycline-induced cardiotoxicity, according to new ... read more

Tackling Cardiac Toxicity of Anticancer Therapies

Aug. 27, 2016 — Researchers are tackling the cardiac toxicity of anticancer ... read more

New Oral Anticoagulants Provide Same Stroke Prevention as Warfarin but Cause Less Bleeding

Aug. 27, 2016 — The new oral anticoagulants provide the same stroke prevention as warfarin but cause less intracranial bleeding, reports an observational study in more than 43,000 ... read more

Alcohol-Related Hospitalization Associated With Doubled Stroke Risk in Atrial Fibrillation

Aug. 27, 2016 — Alcohol-related hospitalization is associated with a doubled risk of ischemic stroke risk in patients with non-valvular atrial fibrillation, according to a new study. The observational study was ... read more

Sertraline, Brand Named Zoloft, Improves Functioning in Young Children With Fragile X

Aug. 26, 2016 — Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of ... read more

Aug. 26, 2016 — Researchers have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a ... read more

Bacteria in Smokeless Tobacco Products May Be a Health Concern

Aug. 26, 2016 — Several species of bacteria found in smokeless tobacco products have been associated with opportunistic infections, according to a new paper. An estimated 8 million people use smokeless tobacco ... read more

Sights Set on the Next Generation of Shuttle Peptides to Target the Brain

Aug. 26, 2016 — There is a new and emerging field of drug transporters that have the capacity to reach the brain more efficiently, say researchers, bringing together chemistry, pharmacy and ... read more

Aug. 26, 2016 — A research team has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA. The technique offers, through high-level editing operation, a method to ... read more

Discovery of a Novel Wnt Inhibitor With Potential to Eradicate Colorectal Cancer Stem Cells, Report Researchers

Aug. 26, 2016 — A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. The inhibitor may provide a ... read more

Aug. 26, 2016 — Chemists have significantly improved upon the synthesis of a molecule related to muscle and neuronal function. A research team has been busy trying to crack the puzzle of the insecticide ryanodine, a ... read more

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