Pharmacology News
July 23, 2016

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More Pharmacology News
July 23, 2016

Chronic Low Back Pain Linked to Higher Rates of Illicit Drug Use

July 21, 2016 — People living with chronic low back pain (cLBP) are more likely to use illicit drugs -- including marijuana, cocaine, heroin, and methamphetamine -- compared to those without back pain, reports a ... read more

Virtual Development of Real Drugs

July 21, 2016 — Inside the human body, the same drug can interact with multiple molecules. This phenomenon is known as 'polypharmacology' and, according to the interaction, a drug can cure a disease or ... read more

Diversifying Clinical Science to Represent Diverse Populations

July 20, 2016 — Despite increasing attention to issues of diversity in scientific research, participant populations in behavioral science tend to be relatively homogeneous. A special series in Clinical Psychological ... read more

Combining New and Old Drugs Improves Survival for Soft-Tissue Cancer Patients

July 20, 2016 — Adding a novel monoclonal antibody therapy called olaratumab to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, according to a multicenter ... read more

Potential Drug Candidates Could Intervene in Deadly Diseases

July 20, 2016 — Scientists have identified drug candidates that can boost a cell's ability to catch the 'typos' in protein production that can cause a deadly disease called amyloidosis, revealing a ... read more

July 20, 2016 — Researchers have engineered a clinically relevant bacterium to produce cancer drugs and then self-destruct and release the drugs at the site of tumors. The approach enables continual production and ... read more

Uncovering a New Principle in Chemotherapy Resistance in Breast Cancer

July 20, 2016 — A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 ... read more

Anti-Tumor Antibodies Could Counter Atherosclerosis, Study Finds

July 20, 2016 — Investigators have learned the signal that tumor cells display on their surfaces to protect themselves from being devoured by the immune system also plays a role in enabling atherosclerosis, the ... read more

Plant-Based Polio Booster Vaccine

July 20, 2016 — Scientists have developed an oral vaccine booster for polio by manipulating plants to express a protein found in the polio virus. Tests with sera from immunized mice show that the booster confers ... read more

Study Examines Opioid Agonist Therapy Use in Medicare Patients

July 20, 2016 — Few Medicare enrollees appear to be receiving buprenorphine-naloxone, the only opioid agonist therapy for opioid addiction available through Medicare Part D prescription drug coverage, according to a ... read more

FDA Approves Scalpel-Free Brain Surgery for Tremor

July 20, 2016 — The Food and Drug Administration has approved the first focused ultrasound device to treat essential tremor, the most common movement disorder, in patients who do not respond to medication. The ... read more

Dangerous Bacteria Found After Sewer Spills

July 20, 2016 — After a sewer line break, a strain of bacteria found in wastewater tested resistant to vancomycin, an antibiotic considered to be a 'last resort' treatment for serious infections that do ... read more

New Treatment Developed to Prevent Nausea, Vomiting Caused by Chemo

July 20, 2016 — A drug that blocks neurotransmitters could reduce nausea and vomiting caused by chemotherapy, new research has ... read more

July 19, 2016 — Scientists have shown that the most common genetic cause of Parkinson's disease -- a mutant LRRK2 kinase enzyme -- contributes to the formation of inclusions in neurons, resembling one of the ... read more

July 19, 2016 — Researchers have found how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord, where neurons then carry those signals to the brain. Their discovery may ... read more

Juicy News About Cranberries: Blocking Bacterial Infections

July 19, 2016 — Illuminating traditional wisdom with chemistry and biophysics, a research team has characterized the role of compounds in cranberry juice that block the critical first step in bacterial infections, ... read more

Quitting Smoking During Pregnancy: Beneficial for Both Mother and Child

July 19, 2016 — In 80 percent of cases, pregnant women who used nicotine patches or the drug Zyban successively quit smoking, a new study has shown. Even after stopping the use of these products, 60 percent of Zyban ... read more

After Psychiatric Hospital Discharge, Many Patients Are Still Taking Multiple Antipsychotic Drugs

July 19, 2016 — In recent years, measures have been introduced to reduce the rate of 'antipsychotic polypharmacy' -- taking more than one antipsychotic drug -- among patients with schizophrenia and other ... read more

No Significant Difference Found Between Glucose-Lowering Drugs for Risk of Death

July 19, 2016 — Among nearly 120,000 adults with type 2 diabetes, there were no significant differences in the associations between any of 9 available classes of glucose-lowering drugs (alone or in combination) and ... read more

July 19, 2016 — The ability to switch disease-causing genes on and off remains a dream for many physicians, research scientists and patients. Researchers have now programmed a virus to transport the necessary ... read more

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