Pharmacology News
August 27, 2016

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More Pharmacology News
August 27, 2016

Aug. 26, 2016 — Researchers have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a ... read more

Sights Set on the Next Generation of Shuttle Peptides to Target the Brain

Aug. 26, 2016 — There is a new and emerging field of drug transporters that have the capacity to reach the brain more efficiently, say researchers, bringing together chemistry, pharmacy and ... read more

Discovery of a Novel Wnt Inhibitor With Potential to Eradicate Colorectal Cancer Stem Cells, Report Researchers

Aug. 26, 2016 — A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. The inhibitor may provide a ... read more

Experts Say Inexpensive Drug Could Slow Heart Disease for Type 1 Diabetic Patients

Aug. 25, 2016 — Scientists believe a drug commonly prescribed for type 2 diabetes could be routinely taken by type 1 diabetic patients to slow the development or delay heart ... read more

Aug. 25, 2016 — Functional human collagen has been impossible to create in the lab. Now, a team of researchers describes what may be the key to growing functional, natural collagen fibers outside of the body: ... read more

Aug. 25, 2016 — A new decision-making tool helps producers of pharmaceutical and other valuable chemicals make the leap to an entirely new way of ... read more

Targeting Low-Oxygen Patches Inside Lung Cancer Tumors Could Help Prevent Drug Resistance

Aug. 25, 2016 — With the right treatment schedule, medications known as hypoxia-activated prodrugs (HAPs) could help prevent drug resistance in a subtype of lung cancer, according to a ... read more

Immune System Infighting Explains Pancreatic Cancer's Aggression

Aug. 25, 2016 — Conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer, report researchers. Curbing this infighting has the potential to make treatment more ... read more

Researchers Question Process for Reviewing Coverage of 'Off Label' Cancer Drug Use

Aug. 25, 2016 — Physician-researchers have raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which ... read more

Hitching a Ride: Misfiring Drugs Hit the Wrong Targets

Aug. 25, 2016 — Researchers have shown how anti-HIV protein inhibitor drugs can bind to the wrong protein, causing unwanted side ... read more

New Method in Synthesis and Development for Pharmaceuticals

Aug. 25, 2016 — Scientists have developed a new synthetic methods that facilitate the design and synthesis of bioactive compounds and chemical tools for pharmacological studies, the team ... read more

Number of Tuberculosis Cases in India Is Double Current Estimates, Says New Study

Aug. 25, 2016 — The number of cases of tuberculosis (TB) in India may be up to two to three times higher than current estimates, suggests a new study. TB is a bacterial infection, spread through inhaling tiny ... read more

Aug. 25, 2016 — Beads, disks, bowls and rods: scientists have demonstrated the first methodological approach to control the shapes of nanovesicles. This opens doors for the use of nanovesicles in biomedical ... read more

Aug. 25, 2016 — Scientists are testing a drug that could boost levels of critical protective protein in brain. In the study, the team conducted tests in a mouse model of Alzheimer's disease by raising the ... read more

MRI-Guided Focused Ultrasound Effective to Treat Essential Tremor

Aug. 24, 2016 — Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a new ... read more

Simulated Patient Study Sheds New Light on Antibiotic Use in India

Aug. 24, 2016 — As a result of the overuse or misuse of antibiotics, antimicrobial resistant superbugs represent an extraordinary threat to global health. This threat is particularly great in India, the world's ... read more

Conflicts Subverting Improved Health Conditions in Eastern Mediterranean Region

Aug. 24, 2016 — Improved health conditions and life expectancy over the past 20 years in the Eastern Mediterranean Region are being subverted by wars and civil unrest, according to a new scientific ... read more

We Are All 'Wired' for Addiction, Says Researcher

Aug. 24, 2016 — Drug addicts and non-addicts may have more in common than ever thought, according to a researcher who found that to some degree, everyone’s brain is “wired” to become ... read more

Aug. 24, 2016 — A protein often located on the surface of fat droplets within cells -- and especially abundant in the muscles of endurance athletes -- can kick-start the more efficient and healthful breakdown of ... read more

Enigmatic Molecules Maintain Equilibrium Between Fighting Infection, Inflammatory Havoc

Aug. 24, 2016 — Special RNA molecules called long non-coding RNAs are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders. The discovery offers a potential drug ... read more

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