Pharmacology News
August 24, 2016

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updated 9:30pm EDT

More Pharmacology News
August 24, 2016

Scientists Track Metabolic Pathways to Find Drug Combination for Pancreatic Cancer

Aug. 24, 2016 — Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown ... read more

Do the Tools to Quantify Addiction Help to Define It?

Aug. 24, 2016 — Understanding what counts as an addiction, and what can be done to address it is the work of researchers across many disciplines. But what tools are used to ‘measure’ addiction, and are these ... read more

Mechanism That Alters Neural Excitability Offers Window Into Neuropsychiatric Disease

Aug. 23, 2016 — Researchers show, for the first time, that the well-known mechanism of gene expression control -- dynamic changes in DNA methylation -- is also involved in changes to the excitability of neural ... read more

Recommended Blood Pressure Targets for Diabetes Are Being Challenged

Aug. 23, 2016 — The Swedish National Board of Health and Welfare recently raised the recommended target blood pressure for patients with diabetes. This may lead to more patients suffering from stroke or heart ... read more

New Zika Clone Could Be New Model for Developing Vaccine

Aug. 23, 2016 — Stopping the explosive spread of Zika virus -- which can lead to birth defects in babies born to infected mothers -- depends on genetic insights gleaned through new tools and models. Researchers ... read more

Study Uses Geo-Mapping to Identify 'Hot Spots' for Use of Fentanyl and Other Opiates

Aug. 23, 2016 — As the US experiences sharp increases in drug overdoses, researchers are using geo-mapping to look at the state, neighborhood by neighborhood, to identify 'hot spots' where the use of ... read more

Fall in UK Cardiovascular Disease Toll Not Equal Among All Four Countries or Genders

Aug. 22, 2016 — UK deaths from heart disease and stroke have plummeted by almost 70 percent over the past 30 years, but these improvements have not been equally distributed among all four countries, or between men ... read more

New Drug Target Could Prevent Tolerance, Addiction to Opioids, Study Finds

Aug. 22, 2016 — Researchers have identified a brain mechanism that could be a drug target to help prevent tolerance and addiction to opioid pain medication, such as ... read more

How Melanoma Spreads to Other Organs in the Body

Aug. 22, 2016 — In a landmark discovery, researchers have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. Their work may lead to a cure for the deadly ... read more

Rx Associated With Fracture Risk Infrequently Reduced After Fracture Occurrence

Aug. 22, 2016 — Is the occurrence of a fragility fracture -- where Medicare beneficiaries broke a hip, wrist or shoulder -- a missed opportunity to reduce exposure to prescription drugs associated with fracture ... read more

New Care Plan Improves Crohn’s Disease Complication Outcomes

Aug. 22, 2016 — The first published medical and surgical approach care plan for managing septic perianal Crohn’s disease, a serious complication that occurs in around 40 percent of Crohn’s disease patients has ... read more

Full Adherence to Guideline-Recommend Therapies Associated With Lower Rate of MACE

Aug. 22, 2016 — MINERVA results demonstrate full adherence to guideline-recommended therapies associated with lower rate of a second major cardiovascular event and cost ... read more

Aug. 22, 2016 — The current test used in developing nations to diagnose tuberculosis is error-prone, complicated and slow. Furthermore, patients in these resource-limited areas can't easily travel back to a ... read more

Color-Graded Pictogram Label to Reduce Medicine-Related Traffic Crashes Found Ineffective

Aug. 21, 2016 — A new study questions the effectiveness of using pictogram message on the labels of anxiety and sleep medications that interfere with driving -- an approach this is currently implemented across ... read more

Aug. 21, 2016 — The developing world is awash in substandard, degraded or falsified medications, which can either directly harm users or deprive them of needed treatment. And with internet sales of medications on ... read more

Study Finds Better Definition of Homelessness May Help Minimize HIV Risk

Aug. 19, 2016 — Being homeless puts people at greater risk of HIV infection than those with stable housing, but targeting services to reduce risk behaviors is often complicated by fuzzy definitions of homelessness, ... read more

Aug. 19, 2016 — Rheumatoid arthritis patients taking medications that inhibit interleukin-1beta, a molecule that stimulates the immune system, are 300 times more likely to experience invasive Group A Streptococcal ... read more

'Missing Evolutionary Link' of a Widely Used Natural Drug Source Found

Aug. 19, 2016 — A well-known family of natural compounds, called “terpenoids,” have a curious evolutionary origin. In particular, one question relevant to future drug discovery has puzzled scientists: exactly ... read more

Aug. 19, 2016 — Researchers have revealed, for the first time, the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of ... read more

New Oral Diabetes Drugs May Also Protect Patients' Kidney Health

Aug. 18, 2016 — In a clinical trial of patients with type 2 diabetes, canagliflozin (a sodium-glucose cotransporter 2 inhibitor) slowed kidney function decline to a greater extent than glimepiride (a sulfonylurea), ... read more

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