Pharmacology News
August 26, 2016

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August 26, 2016

Sights Set on the Next Generation of Shuttle Peptides to Target the Brain

Aug. 26, 2016 — There is a new and emerging field of drug transporters that have the capacity to reach the brain more efficiently, say researchers, bringing together chemistry, pharmacy and ... read more

Targeting Low-Oxygen Patches Inside Lung Cancer Tumors Could Help Prevent Drug Resistance

Aug. 25, 2016 — With the right treatment schedule, medications known as hypoxia-activated prodrugs (HAPs) could help prevent drug resistance in a subtype of lung cancer, according to a ... read more

Researchers Question Process for Reviewing Coverage of 'Off Label' Cancer Drug Use

Aug. 25, 2016 — Physician-researchers have raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which ... read more

Hitching a Ride: Misfiring Drugs Hit the Wrong Targets

Aug. 25, 2016 — Researchers have shown how anti-HIV protein inhibitor drugs can bind to the wrong protein, causing unwanted side ... read more

New Method in Synthesis and Development for Pharmaceuticals

Aug. 25, 2016 — Scientists have developed a new synthetic methods that facilitate the design and synthesis of bioactive compounds and chemical tools for pharmacological studies, the team ... read more

Number of Tuberculosis Cases in India Is Double Current Estimates, Says New Study

Aug. 25, 2016 — The number of cases of tuberculosis (TB) in India may be up to two to three times higher than current estimates, suggests a new study. TB is a bacterial infection, spread through inhaling tiny ... read more

Aug. 25, 2016 — Beads, disks, bowls and rods: scientists have demonstrated the first methodological approach to control the shapes of nanovesicles. This opens doors for the use of nanovesicles in biomedical ... read more

Aug. 25, 2016 — Scientists are testing a drug that could boost levels of critical protective protein in brain. In the study, the team conducted tests in a mouse model of Alzheimer's disease by raising the ... read more

MRI-Guided Focused Ultrasound Effective to Treat Essential Tremor

Aug. 24, 2016 — Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a new ... read more

Simulated Patient Study Sheds New Light on Antibiotic Use in India

Aug. 24, 2016 — As a result of the overuse or misuse of antibiotics, antimicrobial resistant superbugs represent an extraordinary threat to global health. This threat is particularly great in India, the world's ... read more

Conflicts Subverting Improved Health Conditions in Eastern Mediterranean Region

Aug. 24, 2016 — Improved health conditions and life expectancy over the past 20 years in the Eastern Mediterranean Region are being subverted by wars and civil unrest, according to a new scientific ... read more

We Are All 'Wired' for Addiction, Says Researcher

Aug. 24, 2016 — Drug addicts and non-addicts may have more in common than ever thought, according to a researcher who found that to some degree, everyone’s brain is “wired” to become ... read more

Aug. 24, 2016 — A protein often located on the surface of fat droplets within cells -- and especially abundant in the muscles of endurance athletes -- can kick-start the more efficient and healthful breakdown of ... read more

Enigmatic Molecules Maintain Equilibrium Between Fighting Infection, Inflammatory Havoc

Aug. 24, 2016 — Special RNA molecules called long non-coding RNAs are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders. The discovery offers a potential drug ... read more

'Reversible' Blood Thinner May Cut Bleeding Risk

Aug. 24, 2016 — Researchers have developed an antibody that blocks the formation of blood clots without triggering bleeding, a serious risk associated with current blood ... read more

Scientists Track Metabolic Pathways to Find Drug Combination for Pancreatic Cancer

Aug. 24, 2016 — Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown ... read more

Concussions and Brain Injury: Can Omega-3 Intake Aid in Brain Health Recovery?

Aug. 24, 2016 — The treatment of concussions and traumatic brain injury (TBI) is a clinical challenge. Clinical studies thus far have failed to identify an effective treatment strategy when a combination of targets ... read more

Study Shows Diabetes Treatment Helps Reduce Weight in Children With Autism

Aug. 24, 2016 — A drug that's been used for decades in the treatment of type 2 diabetes is proving effective in helping to control weight gain in children who are treated for autism spectrum disorder, according ... read more

Calcium Channel Blockers Caught in the Act at Atomic Level

Aug. 24, 2016 — Atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects by acting at different sites on the ... read more

How Do Antidepressants Trigger Fear and Anxiety?

Aug. 24, 2016 — Scientists have mapped out a serotonin-driven anxiety circuit that may explain 'anxiety' side effect of antidepressants. More than 100 million people worldwide take selective serotonin ... read more

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