Featured Research

from universities, journals, and other organizations

New Drug For Deadly Infection Shows Favorable Results In Preliminary Trials

Date:
June 4, 1997
Source:
Johns Hopkins Children's Center
Summary:
A new drug may help prevent respiratory syncytial virus (RSV), which hospitalizes over 90,000 infants each year in the United States. Preliminary testing took place at Georgetown University Medical Center.

WASHINGTON, DC -- A new drug to prevent a form of pneumonia that kills 4,500 infants a year in the United States shows promise after preliminary clinical testing at Georgetown University Medical Center and nine other centers in the U.S.

The new drug, called MEDI-493, has undergone a double-blind, placebo controlled, dose escalation, multi-center, phase I/II trial evaluating important safety and pharmacological properties for treatment of respiratory syncytial virus in infants. MedImmune Inc. of Gaithersburg, MD, which supported this trial, has the exclusive worldwide marketing and manufacturing rights for MEDI-493. Respiratory syncytial virus (RSV) afflicts the underdeveloped lungs of premature infants, and is responsible for the hospitalization of 90,000 infants each year in the United States alone. The cost of treating a high-risk infant for RSV can be over $70,000.

Currently, a drug called RespiGam™ (Respiratory Syncytial Virus Immune Globulin Intravenous (Human)) is given to high-risk infants to prevent hospitalization due to RSV infection. At risk infants receive RespiGam™ once a month in a lengthy two to four hour infusion. RespiGam ™ is marketed in the U.S. by MedImmune in partnership with American Home Products Corporation.

MEDI-493 can be given more rapidly by infusion or by intra-muscular injection. If successful in phase III clinical trials, MEDI-493 has the potential to enhance patient care, reduce costs associated with drug administration and improve convenience for parents, physicians and nurses.

Dr. K.N. Siva Subramanian, the principal investigator in this study, presented the findings last month at the Pediatric Societies' Annual Meeting in Washington, DC.

# # # Commercialization of MEDI-493 will require prior approval from regulatory authorities, including the Food and Drug Administration in the United States. There can be no assurances that such approvals will be obtained.


Story Source:

The above story is based on materials provided by Johns Hopkins Children's Center. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Children's Center. "New Drug For Deadly Infection Shows Favorable Results In Preliminary Trials." ScienceDaily. ScienceDaily, 4 June 1997. <www.sciencedaily.com/releases/1997/06/970604092145.htm>.
Johns Hopkins Children's Center. (1997, June 4). New Drug For Deadly Infection Shows Favorable Results In Preliminary Trials. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/1997/06/970604092145.htm
Johns Hopkins Children's Center. "New Drug For Deadly Infection Shows Favorable Results In Preliminary Trials." ScienceDaily. www.sciencedaily.com/releases/1997/06/970604092145.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins