Featured Research

from universities, journals, and other organizations

Fetal Bone Marrow Best Source Of Stem Cells For Transplantation

Date:
June 6, 1997
Source:
Johns Hopkins Children's Center
Summary:
Georgetown research shows that fetal bone marrow is the best source of stem cells for bone marrow transplants, better than umbilical cord blood or adult bone marrow.

WASHINGTON, DC -- Researchers at Georgetown University Medical Center have completed a study comparing the effectiveness of three main sources of stem cells for bone marrow transplantation: fetal bone marrow from spontaneous abortions, umbilical cord blood and adult bone marrow.


The study, done by Maria Michejda, Ph.D. and colleagues at Georgetown, shows that fetal bone marrow is eight times more effective than umbilical cord blood, and 23 times more effective than adult bone marrow for bone marrow transplantation


Besides the shortage of matching donors, the biggest problem with bone marrow transplantation is graft-versus-host disease (GVHD). GVHD occurs when the immune system of the donor's marrow identifies the recipient's body as foreign and tries to destroy it.


The investigators found that compared to cord blood and adult bone marrow, fetal bone marrow contains the highest concentration of CD34+ cells which are responsible for creating new blood cells, and the lowest concentrations of CD-3 cells, which are responsible for identifying and rejecting foreign tissue. The lower the level of CD-3 cells, the lower the chances of GVHD.


The paper was presented last month at the Pediatric Societies' Annual Meeting in Washington, DC.


Story Source:

The above story is based on materials provided by Johns Hopkins Children's Center. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Children's Center. "Fetal Bone Marrow Best Source Of Stem Cells For Transplantation." ScienceDaily. ScienceDaily, 6 June 1997. <www.sciencedaily.com/releases/1997/06/970606123807.htm>.
Johns Hopkins Children's Center. (1997, June 6). Fetal Bone Marrow Best Source Of Stem Cells For Transplantation. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/1997/06/970606123807.htm
Johns Hopkins Children's Center. "Fetal Bone Marrow Best Source Of Stem Cells For Transplantation." ScienceDaily. www.sciencedaily.com/releases/1997/06/970606123807.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins