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Vascular Surgeons Test New Treatment For Abdominal Aneurysms

Date:
March 20, 1998
Source:
Johns Hopkins Medical Institutions
Summary:
Vascular surgeons at Johns Hopkins are participating in a nationwide test of a procedure that uses 3-D images and a metal-supported cloth tube to repair stretched and weakened abdominal arteries before they burst and kill.

Vascular surgeons at Johns Hopkins are participating in a nationwide test of a procedure that uses 3-D images and a metal-supported cloth tube to repair stretched and weakened abdominal arteries before they burst and kill.

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The tube, called a stent graft, is implanted in the abdominal aorta -- the main artery supplying blood to the lower body -- through a small incision in the groin. Blood then passes through the stent graft, taking pressure off the large and weak aorta, and reducing or eliminating the risk of rupture and death. "This seems to be a safe and effective alternative to major surgery," says G. Melville Williams, M.D., chief of vascular surgery and lead investigator for the trial. "Previous studies show patients are out of the hospital quicker, have much less pain and return to pre-operative functioning much faster. Patients usually are discharged on the second day after the procedure, provided tests show the aneurysm is excluded from circulation."

Called silent killers because they often cause no symptoms, aneurysms occur in more than 5 percent of people age 60 and older. The incidence is higher among smokers, although aneurysms usually occur as the normal wear-and-tear aging process weakens the arterial wall. Sometimes they result from trauma or acute or chronic infections. They can be fatal if they leak or rupture.

About 75 percent of aneurysms go undiagnosed unless found unexpectedly during physical exams or picked up on X-rays taken for unrelated reasons.

In the current study, at 16 centers nationwide, physicians take 3-D computed tomography images of the abdomen to determine the exact anatomy of the aneurysm. If physicians feel the stent graft is suitable, it is inserted through an opening in the groin's femoral artery and threaded into the aneurysm using fluoroscopy, or X-ray imaging. The stent's metallic frame is flexible at cold temperatures but stiff at body temperature. This enables the cloth support to expand to fill the necessary space, excluding the aneurysm.

Traditional treatments for abdominal aortic aneurysms require extensive surgery to sew a similar but unsupported cloth tube inside the ballooning aorta.

Williams is accepting 15 patients for the Hopkins study, which is nearly complete. He anticipates that the new treatment will be available once the study is completed. For more information or to volunteer, call 410-955-5165.

The clinical trial is sponsored by Meadox Medicals Inc. (a division of Boston Scientific Corp.), manufacturers of the stent.

--JHMI--

Johns Hopkins Medical Institutions' news releases are available on a PRE-EMBARGOED basis on EurekAlert at http://www.eurekalert.org, Newswise at http://www.newswise.com and from the Office of Communications and Public Affairs' direct e-mail news release service. To enroll, call 410-955-4288 or send e-mail to bsimpkin@welchlink.welch.jhu.edu or 76520.560@compuserve.com.

On a POST-EMBARGOED basis find them at http://hopkins.med.jhu.edu, Quadnet at http://www.quad-net.com, ScienceDaily at http://www.sciencedaily.com or on CompuServe in the SciNews-MedNews library of the Journalism Forum under file extension ".JHM".


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Vascular Surgeons Test New Treatment For Abdominal Aneurysms." ScienceDaily. ScienceDaily, 20 March 1998. <www.sciencedaily.com/releases/1998/03/980320125412.htm>.
Johns Hopkins Medical Institutions. (1998, March 20). Vascular Surgeons Test New Treatment For Abdominal Aneurysms. ScienceDaily. Retrieved April 25, 2015 from www.sciencedaily.com/releases/1998/03/980320125412.htm
Johns Hopkins Medical Institutions. "Vascular Surgeons Test New Treatment For Abdominal Aneurysms." ScienceDaily. www.sciencedaily.com/releases/1998/03/980320125412.htm (accessed April 25, 2015).

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