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Study Shows Efavirenz Promising In Treating Pediatric HIV Infection: Leads To Approval Of New Drug For Treating HIV-Infected Children

Date:
October 1, 1998
Source:
National Institute Of Allergy And Infectious Diseases
Summary:
Investigators have announced results of an interim analysis of the first pediatric study of efavirenz, a new non-nucleoside reverse transcriptase inhibitor that when used in combination with nelfinavir and other antiretrovirals, suppressed HIV replication over a 20-week period in most children.

Investigators of the Pediatric AIDS Clinical Trials Group (PACTG), a network of trial sites supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Child Health and Human Development (NICHD), have announced results of an interim analysis of the first pediatric study of efavirenz, a new non-nucleoside reverse transcriptase inhibitor (NNRTI) that can be taken once daily. The purpose of the study, known as PACTG 382, is to determine the safety, dosing and antiviral effect of efavirenz in combination with antiretrovirals in HIV-infected children. Efavirenz, when used in combination with nelfinavir and other antiretrovirals, suppressed HIV replication over a 20-week period in most children.


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The above story is based on materials provided by National Institute Of Allergy And Infectious Diseases. Note: Materials may be edited for content and length.


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National Institute Of Allergy And Infectious Diseases. "Study Shows Efavirenz Promising In Treating Pediatric HIV Infection: Leads To Approval Of New Drug For Treating HIV-Infected Children." ScienceDaily. ScienceDaily, 1 October 1998. <www.sciencedaily.com/releases/1998/09/980930142623.htm>.
National Institute Of Allergy And Infectious Diseases. (1998, October 1). Study Shows Efavirenz Promising In Treating Pediatric HIV Infection: Leads To Approval Of New Drug For Treating HIV-Infected Children. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/1998/09/980930142623.htm
National Institute Of Allergy And Infectious Diseases. "Study Shows Efavirenz Promising In Treating Pediatric HIV Infection: Leads To Approval Of New Drug For Treating HIV-Infected Children." ScienceDaily. www.sciencedaily.com/releases/1998/09/980930142623.htm (accessed April 19, 2014).

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