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Single Amino Acid Change In Herpes Virus Prevents It From Infecting Neurons

Date:
July 15, 1999
Source:
University Of Chicago Medical Center
Summary:
Researchers at the University of Chicago have found that a single amino acid change in a viral protein called ICP0, stops the herpes virus from entering the nervous system. The finding provides clear evidence of how viruses usurp the machinery of the cells they infect, and reveals a potential new target for a herpes vaccine or future therapies.

Researchers at the University of Chicago have found that a single amino acid change in a viral protein called ICP0, stops the herpes virus from entering the nervous system. The finding provides clear evidence of how viruses usurp the machinery of the cells they infect, and reveals a "potential new target for a herpes vaccine or future therapies," says Bernard Roizman, Ph.D., Joseph Regenstein Distinguished Service professor in the department of molecular genetics & cell biology at the University, and lead author of the paper.


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The above story is based on materials provided by University Of Chicago Medical Center. Note: Materials may be edited for content and length.


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University Of Chicago Medical Center. "Single Amino Acid Change In Herpes Virus Prevents It From Infecting Neurons." ScienceDaily. ScienceDaily, 15 July 1999. <www.sciencedaily.com/releases/1999/07/990715063204.htm>.
University Of Chicago Medical Center. (1999, July 15). Single Amino Acid Change In Herpes Virus Prevents It From Infecting Neurons. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/1999/07/990715063204.htm
University Of Chicago Medical Center. "Single Amino Acid Change In Herpes Virus Prevents It From Infecting Neurons." ScienceDaily. www.sciencedaily.com/releases/1999/07/990715063204.htm (accessed April 19, 2014).

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