Featured Research

from universities, journals, and other organizations

Linezolid Is Highly Effective Against Antibiotic-Resistant Infections

Date:
August 17, 1999
Source:
Northwestern University
Summary:
A study by researchers at Northwestern University Medical School and Northwestern Memorial Hospital reports that linezolid, a new antibiotic, is highly effective against a range of gram-positive bacteria, including several antibiotic-resistant enterococci and staphylococci.

Gram-positive bacterial infections are on the rise, as are the number of new strains of bacteria that are increasingly resistant to antibiotics. For patients infected with these drug-resistant organisms, there are few, if any, therapeutic options.

Related Articles


Now, a study by researchers at Northwestern University Medical School and Northwestern Memorial Hospital reports that linezolid, a new antibiotic, is highly effective against a range of gram-positive bacteria, including several antibiotic-resistant enterococci and staphylococci.

The study, which appears in the August issue of the journal Antimicrobial Agents and Chemotherapy, describes the largest laboratory experience to date with linezolid.

Infectious disease specialist Gary A. Noskin, M.D., and co-researchers from Northwestern compared the activity of linezolid with that of a number of currently available antibiotics against approximately 4,000 fresh bacteria isolates of streptococci, enterococci and staphylococci.

They found that linezolid showed potent activity against all isolates tested and was the most active antibiotic against oxacillin-resistant staphylococci and vancomycin-resistant enterococci, including both VanA or VanB types. Against all vancomycin-susceptible bacteria, the activity of linezolid was comparable to that of vancomycin.

Based on these in vitro results, as well as his clinical experience with this drug, Noskin commented: "Linezolid appears to be a promising new antibiotic for the treatment of a wide range of gram-positive infections, including vancomycin-resistant enterococci."

Noskin is an associate professor of medicine at the Medical School and medical director of Infection Control and Prevention at Northwestern Memorial Hospital. His co-authors on this study were Farida Siddiqui, Valentina Stosor, M.D., Donna Hacek and Lance R. Peterson, M.D., professor of pathology, Northwestern University Medical School.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Linezolid Is Highly Effective Against Antibiotic-Resistant Infections." ScienceDaily. ScienceDaily, 17 August 1999. <www.sciencedaily.com/releases/1999/08/990817065229.htm>.
Northwestern University. (1999, August 17). Linezolid Is Highly Effective Against Antibiotic-Resistant Infections. ScienceDaily. Retrieved April 1, 2015 from www.sciencedaily.com/releases/1999/08/990817065229.htm
Northwestern University. "Linezolid Is Highly Effective Against Antibiotic-Resistant Infections." ScienceDaily. www.sciencedaily.com/releases/1999/08/990817065229.htm (accessed April 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, April 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Wound-Healing Laser Soon to Be a Reality Israeli Scientist

Wound-Healing Laser Soon to Be a Reality Israeli Scientist

Reuters - Innovations Video Online (Apr. 1, 2015) Israeli scientists says laser bonding of tissue allows much faster healing and less scarring. Amy Pollock has more. Video provided by Reuters
Powered by NewsLook.com
Liberia Sees Resurgence of Drug Trafficking as Ebola Wanes

Liberia Sees Resurgence of Drug Trafficking as Ebola Wanes

AFP (Apr. 1, 2015) The governments of Liberia and Sierra Leone have been busy fighting the menace created by the deadly Ebola virus, but illicit drug lords have taken advantage of the situation to advance the drug trade. Duration: 01:12 Video provided by AFP
Powered by NewsLook.com
Stigma Stalks India's Leprosy Sufferers as Disease Returns

Stigma Stalks India's Leprosy Sufferers as Disease Returns

AFP (Apr. 1, 2015) The Indian government declared victory over leprosy in 2005, but the disease is making a comeback in some parts of the country, with more than a hundred thousand lepers still living in colonies, shunned from society. Duration: 02:41 Video provided by AFP
Powered by NewsLook.com
7-Year-Old Girl Gets 3-D Printed 'robohand'

7-Year-Old Girl Gets 3-D Printed 'robohand'

AP (Mar. 31, 2015) Although she never had much interest in prosthetic limbs before, Faith Lennox couldn&apos;t wait to slip on her new robohand. The 7-year-old, who lost part of her left arm when she was a baby, grabbed it as soon as it came off a 3-D printer. (March 31) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins