Featured Research

from universities, journals, and other organizations

Linezolid Is Highly Effective Against Antibiotic-Resistant Infections

Date:
August 17, 1999
Source:
Northwestern University
Summary:
A study by researchers at Northwestern University Medical School and Northwestern Memorial Hospital reports that linezolid, a new antibiotic, is highly effective against a range of gram-positive bacteria, including several antibiotic-resistant enterococci and staphylococci.

Gram-positive bacterial infections are on the rise, as are the number of new strains of bacteria that are increasingly resistant to antibiotics. For patients infected with these drug-resistant organisms, there are few, if any, therapeutic options.

Now, a study by researchers at Northwestern University Medical School and Northwestern Memorial Hospital reports that linezolid, a new antibiotic, is highly effective against a range of gram-positive bacteria, including several antibiotic-resistant enterococci and staphylococci.

The study, which appears in the August issue of the journal Antimicrobial Agents and Chemotherapy, describes the largest laboratory experience to date with linezolid.

Infectious disease specialist Gary A. Noskin, M.D., and co-researchers from Northwestern compared the activity of linezolid with that of a number of currently available antibiotics against approximately 4,000 fresh bacteria isolates of streptococci, enterococci and staphylococci.

They found that linezolid showed potent activity against all isolates tested and was the most active antibiotic against oxacillin-resistant staphylococci and vancomycin-resistant enterococci, including both VanA or VanB types. Against all vancomycin-susceptible bacteria, the activity of linezolid was comparable to that of vancomycin.

Based on these in vitro results, as well as his clinical experience with this drug, Noskin commented: "Linezolid appears to be a promising new antibiotic for the treatment of a wide range of gram-positive infections, including vancomycin-resistant enterococci."

Noskin is an associate professor of medicine at the Medical School and medical director of Infection Control and Prevention at Northwestern Memorial Hospital. His co-authors on this study were Farida Siddiqui, Valentina Stosor, M.D., Donna Hacek and Lance R. Peterson, M.D., professor of pathology, Northwestern University Medical School.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Linezolid Is Highly Effective Against Antibiotic-Resistant Infections." ScienceDaily. ScienceDaily, 17 August 1999. <www.sciencedaily.com/releases/1999/08/990817065229.htm>.
Northwestern University. (1999, August 17). Linezolid Is Highly Effective Against Antibiotic-Resistant Infections. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/1999/08/990817065229.htm
Northwestern University. "Linezolid Is Highly Effective Against Antibiotic-Resistant Infections." ScienceDaily. www.sciencedaily.com/releases/1999/08/990817065229.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Raw: World's Oldest Man Lives in Japan

Raw: World's Oldest Man Lives in Japan

AP (Aug. 20, 2014) — A 111-year-old Japanese was certified as the world's oldest man by Guinness World Records on Wednesday. Sakari Momoi, a native of Fukushima in northern Japan, was given a certificate at a hospital in Tokyo. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Do More Wedding Guests Make A Happier Marriage?

Do More Wedding Guests Make A Happier Marriage?

Newsy (Aug. 20, 2014) — A new study found couples who had at least 150 guests at their weddings were more likely to report being happy in their marriages. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) — Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins