Featured Research

from universities, journals, and other organizations

UF Cardiologists Call For Rigorous Study Of Viagra And Cardiovascular Disease

Date:
September 3, 1999
Source:
University Of Florida Health Science Center
Summary:
University of Florida cardiologists say there is no solid scientific evidence that patients with cardiovascular disease face a higher risk of death when they take Viagra.

GAINESVILLE, Fla.---University of Florida cardiologists say there is no solid scientific evidence that patients with cardiovascular disease face a higher risk of death when they take Viagra.

Related Articles


Viagra, the tradename for the drug sildenafil citrate, is used to treat erectile dysfunction, which affects an estimated 150 million men worldwide. Many of these men have cardiovascular disease.

An outpouring of media attention ensued after a handful of patients with cardiovascular disease died after taking the popular medication. It's true that Viagra and nitroglycerin, commonly used to treat the chest pain known as angina, don't mix. Patients taking nitroglycerin shouldn't use Viagra because it can cause dangerous drops in blood pressure; likewise, patients who use Viagra should not take nitroglycerin for at least 24 hours. But there is no scientific proof Viagra is directly associated with death in cardiovascular disease patients, says Dr. Carl J. Pepine, professor and chief of cardiovascular medicine at UF's College of Medicine.

Pepine and UF colleague Dr. C. Richard Conti led a symposium on managing erectile dysfunction in the cardiac patient Aug. 26 at the meeting of the 21st Congress of the European Society of Cardiology in Barcelona, Spain.

"Some men with cardiovascular disease die, men with cardiovascular disease have a high frequency of erectile dysfunction, and some men with erectile dysfunction and cardiovascular disease take Viagra and die, too," Pepine said. "But there is no objective evidence to directly relate an increased frequency of death with Viagra use in these patients. Everything we have examined so far suggests that the frequency of death is about the same as in patients with heart disease who received a placebo."

Pepine is calling for a controlled clinical trial comparing Viagra with placebo in about 5,000 heart disease patients, which he said would give scientists the answers they need. Earlier this year, Pepine and Conti co-authored a paper in a supplement to The American Journal of Cardiology that described an analysis of 11 studies of the drug in patients with erectile dysfunction and cardiovascular disease caused by reduced blood flow to the heart who were not taking nitrates; findings showed these patients tolerated the medication well.

What's more, it's possible that Viagra may even ease certain problems many patients with cardiovascular disease experience, such as depression.

"The adverse outcomes of cardiovascular disease, such as heart attack or death, are due to a complex interplay of many risk factor conditions that aggravate the disease and its expression, including a host of psychological problems like depression and poor self-image as well as some physical factors," Pepine explained.

In turn, Viagra's advantages may even play a role in reducing the overall risk of cardiovascular events such as heart attack or death, he hypothesized.

"We believe Viagra may be safer than what is commonly perceived," he said.


Story Source:

The above story is based on materials provided by University Of Florida Health Science Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Florida Health Science Center. "UF Cardiologists Call For Rigorous Study Of Viagra And Cardiovascular Disease." ScienceDaily. ScienceDaily, 3 September 1999. <www.sciencedaily.com/releases/1999/09/990902143440.htm>.
University Of Florida Health Science Center. (1999, September 3). UF Cardiologists Call For Rigorous Study Of Viagra And Cardiovascular Disease. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/1999/09/990902143440.htm
University Of Florida Health Science Center. "UF Cardiologists Call For Rigorous Study Of Viagra And Cardiovascular Disease." ScienceDaily. www.sciencedaily.com/releases/1999/09/990902143440.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins