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Signs Of The Ancient Mariner: Scientists Locate Elements Implicated In Human Genetic Disorders

Date:
September 29, 1999
Source:
Cold Spring Harbor Laboratory
Summary:
In a study published in the September issue of Genome Research, Lawrence Reiter, James Lupski (Baylor College of Medicine), and colleagues use fluorescent imaging to locate 109 mariner elements across the human genome, revealing potential undiscovered links between these elements and other hereditary human diseases.

Chromosomes swap DNA to create variety in the gene pool, but disorders can result if the exchanged regions don't match up properly. Recent studies suggest genetic elements called mariner transposons stimulate such mismatching exchanges underlying disorders like Charcot-Marie-Tooth disease and hereditary neuropathy.


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The above story is based on materials provided by Cold Spring Harbor Laboratory. Note: Materials may be edited for content and length.


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Cold Spring Harbor Laboratory. "Signs Of The Ancient Mariner: Scientists Locate Elements Implicated In Human Genetic Disorders." ScienceDaily. ScienceDaily, 29 September 1999. <www.sciencedaily.com/releases/1999/09/990929022428.htm>.
Cold Spring Harbor Laboratory. (1999, September 29). Signs Of The Ancient Mariner: Scientists Locate Elements Implicated In Human Genetic Disorders. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/1999/09/990929022428.htm
Cold Spring Harbor Laboratory. "Signs Of The Ancient Mariner: Scientists Locate Elements Implicated In Human Genetic Disorders." ScienceDaily. www.sciencedaily.com/releases/1999/09/990929022428.htm (accessed April 24, 2014).

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