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Human genome

The human genome is the genome of Homo sapiens. It is made up of 23 chromosome pairs with a total of about 3 billion DNA base pairs. There are 24 distinct human chromosomes: 22 autosomal chromosomes, plus the sex-determining X and Y chromosomes. Chromosomes 1-22 are numbered roughly in order of decreasing size. Somatic cells usually have one copy of chromosomes 1-22 from each parent, plus an X chromosome from the mother, and either an X or Y chromosome from the father, for a total of 46. There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further.

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Health & Medicine News

September 26, 2026

A new analysis suggests mammograms may lead to far less breast cancer overdiagnosis than some earlier studies indicated. Researchers reexamined all eight major randomized screening trials and ...
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Tirzepatide, sold as Mounjaro and Zepbound, activated calorie-burning brown fat in obese mice, revealing a potential metabolic effect beyond appetite suppression. If confirmed in humans, the finding could help explain the drug’s powerful benefits ...
Scientists discovered rare flavoalkaloids in Cannabis leaves for the first time, along with dozens of other phenolic compounds that had never been reported in the plant. The findings suggest that ...
A major analysis suggests Phelan-McDermid syndrome, a genetic disorder closely linked to autism, may affect about 1 in 7,300 people and more than 45,000 Americans. Researchers warn that thousands of ...
Researchers used CRISPR to remove CD33 from donor stem cells, potentially giving doctors a way to attack aggressive blood cancers without destroying the healthy cells patients need after a ...
A magnet-producing bacterium extended the average lifespan of C. elegans worms by more than 43% while helping protect their neurological and intestinal health. Researchers traced much of the effect to suppression of ferroptosis, a damaging form of ...
Scientists discovered a surprising backup system that lets mammalian cells make the essential amino acid cysteine even when the pathways once considered indispensable are disabled. The same survival ...
A 70-year-old leukemia drug is still revealing new secrets. Researchers found that removing a protein called NUDT5 protected cells from the drug, even though simply blocking the protein had little effect. The unexpected result points to a hidden ...
A newly identified breakdown in communication between nerves and muscles could help explain why people lose strength as they age. Researchers were able to improve muscle strength in an animal model by targeting a key protein, raising hopes that some ...
A large study tracking more than 95,000 people suggests that how you sleep may be linked to your risk of developing dozens of diseases. People who spent more time in REM sleep had lower risks of 83 conditions, including dementia, heart failure, and ...
Children taking GLP-1 medications (such as Victoza, Saxenda, Trulicity, and Ozempic) for weight loss, prediabetes, or type 2 diabetes may face an overlooked risk: nutritional deficiencies. A new ...

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