Contact: Pete Barkey, (734) 764-2220, [email protected]
ANN ARBOR---Researchers at the University of Michigan are reporting that a certain phenomenon, which can occur during heart monitoring, may cause patients to undergo unnecessary procedures on their heart.
The problem is known as electrocardiographic "artifact"---electrical "noise" that can take place during recording of the heart rhythm as a result of body movement or poor skin-to-electrode contact. It can mimic various heart rhythm problems, including ventricular tachycardia, a potentially life-threatening fast heart beat from the bottom chamber of the heart. The results of the study demonstrate that when artifact is misdiagnosed as ventricular tachycardia, patients may undergo diagnostic or therapeutic procedures they otherwise would not need.
The results are published in the Oct. 21 issue of the New England Journal of Medicine.
The study's authors report on 12 patients---six men and six women---who, between 1995 and 1999, underwent at least one unnecessary intervention as a result of artifact being misdiagnosed as ventricular tachycardia. The interventions included intravenous injections of medications, heart catheterization, and in two cases, procedures as drastic as having a pacemaker or defibrillator implanted. In most cases, a correct diagnosis of artifact was made after patients were transferred to the U-M for further evaluation of presumed ventricular tachycardia.
"These findings point out the importance of improved training in the recognition of artifact and the need for a greater degree of suspicion among physicians who manage patients with arrhythmias," says the study's principal investigator, Bradley Knight, M.D., assistant professor of internal medicine in the U-M Health System.
Ventricular tachycardia can lead to palpitations, loss of consciousness or death. Since ventricular tachycardia often indicates a serious underlying structural heart disease, a very thorough evaluation is typically performed, including blood analysis, stress testing, echocardiography and angiography.
The study found the following interventions were performed as a result of artifact being misdiagnosed as ventricular tachycardia:
--One patient had a pacemaker implanted.
--One patient had a defibrillator implanted.
--Three patients received a diagnostic catheterization.
--One patient received a blood transfusion.
--One patient received intravenous nitroglycerin.
--One patient received sublingual nitroglycerin.
--Seven patients received intravenous lidocaine.
Of the 12 patients studied, four were misdiagnosed by a cardiologist, four by a resident physician, three by an emergency medicine physician and one by an electrophysiologist, or heart rhythm specialist.
Knight says artifact has many similarities to ventricular tachycardia, but there are differences that are recognizable with proper training. The key difference has to do with what is called the QRS complex---the electrical symbol that is recorded when the bottom chamber of the heart beats. In cases where artifact is present, a normal QRS reading can be seen in the artifact by a trained expert. Knight says cardiologists and internists are not always adequately trained to recognize artifact, which can be difficult to distinguish from true ventricular tachycardia.
"There needs to be an increased awareness of artifact by physicians and a greater emphasis that it not only occurs, but that a misdiagnosis of artifact can lead to very drastic procedures for patients," Knight says. "It is very important when a patient is diagnosed as having ventricular tachycardia that the actual recordings of the rhythm be carefully reviewed."
He says that further studies are needed to determine how widespread the problem is and to create a greater awareness of the phenomenon, both in the medical community and the general public.
Knight's co-investigators on this study, "Brief Report: The Clinical Impact of Electrocardiographic Artifact that Mimics Ventricular Tachycardia" were Fred Morady, M.D., professor of internal medicine, U-M Health System; Gregory F. Michaud, M.D., assistant professor of internal medicine, U-M Health System; S. Adam Strickberger, M.D., associate professor of internal medicine, U-M Health System; and Frank Pelosi, M.D., lecturer U-M Health System Department of Internal Medicine.
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