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Mutant Proteins Selectively Accumulate In Neurons Affected By Huntington's Disease

Date:
August 14, 2000
Source:
Emory University Health Sciences Center
Summary:
Scientists at Emory University School of Medicine have discovered that fragments of mutant proteins implicated in the development of Huntington's disease selectively accumulate and form aggregates in the nuclei and the axon terminals of neurons in the brain that are specifically known to be affected by the disease.

Scientists at Emory University School of Medicine have discovered that fragments of mutant proteins implicated in the development of Huntington's disease selectively accumulate and form aggregates in the nuclei and the axon terminals of neurons in the brain that are specifically known to be affected by the disease. The finding may help explain why these mutant proteins, although they are widely expressed throughout the body, kill only certain neurons within the striatum and cortex of the brain.


Story Source:

The above story is based on materials provided by Emory University Health Sciences Center. Note: Materials may be edited for content and length.


Cite This Page:

Emory University Health Sciences Center. "Mutant Proteins Selectively Accumulate In Neurons Affected By Huntington's Disease." ScienceDaily. ScienceDaily, 14 August 2000. <www.sciencedaily.com/releases/2000/08/000803075557.htm>.
Emory University Health Sciences Center. (2000, August 14). Mutant Proteins Selectively Accumulate In Neurons Affected By Huntington's Disease. ScienceDaily. Retrieved April 25, 2014 from www.sciencedaily.com/releases/2000/08/000803075557.htm
Emory University Health Sciences Center. "Mutant Proteins Selectively Accumulate In Neurons Affected By Huntington's Disease." ScienceDaily. www.sciencedaily.com/releases/2000/08/000803075557.htm (accessed April 25, 2014).

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