Featured Research

from universities, journals, and other organizations

"Cool" Therapy Reduces Brain Damage And Death From Stroke

Date:
September 1, 2000
Source:
American Heart Association
Summary:
Lowering the body temperature by about one degree within a few hours of a stroke can reduce brain damage and the risk of death, according to a study in this month's Stroke: Journal of the American Heart Association.

DALLAS, Sept. 1 -- Lowering the body temperature by about one degree within a few hours of a stroke can reduce brain damage and the risk of death, according to a study in this month's Stroke: Journal of the American Heart Association. Researchers in Copenhagen, Denmark, pumped cool air into a thermal blanket to induce mild hypothermia (low body temperature) in 17 awake patients soon after they suffered strokes, then maintained the cooler body temperatures for six hours. Those receiving the cooling therapy had a six-month survival rate nearly twice that of a control group of 56 patients who weren't treated with hypothermia.

This study is the first to investigate hypothermia's effect in awake patients and compare their recovery with untreated controls.

"By showing that hypothermia can be successfully used without anesthesia, we have suggested a method of treatment that appears to be low in cost and applicable in most hospitals involved in stroke treatment," says Lars Kammersgaard, M.D., lead author of the study. "If future trials support our findings, the majority of stroke patients may be able to benefit from this treatment in the near future."

Before this study, Kammersgaard says, intervention with hypothermia has been examined only on a limited basis, and putting patients under full anesthesia has always been part of the cooling procedure. However, the researchers in this group were able to work with conscious patients by giving them injections of a drug to control shivering associated with the cooling treatment. On average, body temperatures were reduced by 1.3 degrees Celsius- from 36.8 to 35.5 degrees and some reduction continued for up to four hours after treatment was discontinued.

"By reducing the body temperature in the stroke patient, the brain receives cooled blood," Kammersgaard says. "Animal studies involving hypothermia strongly suggest that decreased brain temperature causes less destruction of brain tissue."

Kammersgaard says there is also evidence to support the idea that people who have low body temperature at the time of hospital admission tend to have lower mortality and better overall outcomes after a stroke.

Kammersgaard's group has documented in animal studies that a decrease of just one degree Celsius in the body temperature of stroke patients at admission is related to smaller regions of brain injury and an 80 percent reduction in the risk of death after stroke.

Because of the relatively small number of patients involved, Kammersgaard emphasizes that no firm conclusions can be drawn from this study. But a much larger randomized clinical trial involving 1,000 stroke patients in Denmark, Norway and Sweden is currently being organized using the same type of treatment.

"Hypothermia seems to have the strongest potential of any stroke treatment, but further study is necessary to determine the full extent of its benefits," he says. "In the present study, for example, we were not able to conclude how much effect hypothermia has on the degree of paralysis in stroke patients, but this will be addressed when the new study is launched within the next few months."

Co-authors include: B.H. Rasmussen, M.D.; H.S. Jorgensen, DMSci.; J. Reith, M.D.; U. Weber, M.D.; and T. S. Olsen, DMSci.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. ""Cool" Therapy Reduces Brain Damage And Death From Stroke." ScienceDaily. ScienceDaily, 1 September 2000. <www.sciencedaily.com/releases/2000/09/000901080235.htm>.
American Heart Association. (2000, September 1). "Cool" Therapy Reduces Brain Damage And Death From Stroke. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2000/09/000901080235.htm
American Heart Association. ""Cool" Therapy Reduces Brain Damage And Death From Stroke." ScienceDaily. www.sciencedaily.com/releases/2000/09/000901080235.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins