Featured Research

from universities, journals, and other organizations

New Research Finds Link Between Gum Disease, Acute Heart Attacks

Date:
November 13, 2000
Source:
University Of North Carolina At Chapel Hill
Summary:
Heart attack survivors who suffer advanced gum disease show significantly higher levels of a protein in their blood called C-reactive protein (CRP) than such patients without gum disease, new University of North Carolina at Chapel Hill research indicates.

CHAPEL HILL -- Heart attack survivors who suffer advanced gum disease show significantly higher levels of a protein in their blood called C-reactive protein (CRP) than such patients without gum disease, new University of North Carolina at Chapel Hill research indicates.

Related Articles


The findings, presented Sunday (Nov. 12) during a news conference at the annual American Heart Association meeting in New Orleans, suggest that the presence of gum disease might increase the risk of a second heart attack in people with a history of heart disease.

"Not only did the heart attack patients with periodontal disease have higher levels of CRP than those without gum disease, but the CRP levels were directly related to the severity of the gum disease," said Dr. Efthymios N. Deliargyris, an interventional cardiologist and a member of the Center for Oral and Systemic Diseases at UNC-CH. "The more severe the gum disease, the higher the CRP levels."

Besides Deliargyris, also an instructor in medicine at the UNC-CH School of Medicine, study investigators were Drs. Steven Offenbacher, professor of periodontology and center director, James D. Beck, professor of dental ecology, both at the UNC-CH School of Dentistry, and Sidney C. Smith Jr., chief of cardiology and past president of the American Heart Association.

"We know a lot of risk factors for heart attacks, including high blood pressure, high cholesterol, diabetes and cigarette smoking, but all those combined only explain about two-thirds of heart attacks," Deliargyris said. "Since about a third of people who suffer heart attacks don't have those risk factors, there's a wide search going on for other conditions that may contribute to increased risk."

Studies at UNC-CH and elsewhere have linked periodontal disease -- an advanced form of gingivitis -- with increased risk of heart attacks, but it has been unclear what the two conditions have in common, the physician said.

"The one thing we know the two conditions share is that they tend to initiate an immune response, also called an inflammatory response, in the body," he said. "The most common marker for this response is this C-reactive protein, which is considered predictive of future adverse events like heart attack." To learn how common severe gum disease was in heart attack victims, the UNC-CH team conducted their pilot study of 38 heart attack patients and matched them with a comparable group of 38 other people without known heart disease. Researchers found a high percentage of the former had periodontal disease -- 85 percent -- as compared with only 29 percent of the controls.

"The most exciting finding was that among people with a heart attack, those with periodontal disease had much higher CRP levels than those with a heart attack but no periodontal disease," Deliargyris said. "It seems that the presence of periodontal disease on top of a heart attack has a synergistic effect and a very accentuated CRP release."

Despite its small size, the study findings are the first of their kind and potentially very important, he said.

"This gives us an insight into possible mechanisms underlying the association between gum disease and heart disease," Deliargyris said. "Now we believe that patients with a heart attack and periodontal disease have an exaggerated inflammatory response with higher CRP levels that might put them at risk for future heart attacks. This work also raises the possibility that by treating severe gum disease in people with heart attacks, we might be able to reduce their CRP levels and their risk of another heart attack."


Story Source:

The above story is based on materials provided by University Of North Carolina At Chapel Hill. Note: Materials may be edited for content and length.


Cite This Page:

University Of North Carolina At Chapel Hill. "New Research Finds Link Between Gum Disease, Acute Heart Attacks." ScienceDaily. ScienceDaily, 13 November 2000. <www.sciencedaily.com/releases/2000/11/001113071724.htm>.
University Of North Carolina At Chapel Hill. (2000, November 13). New Research Finds Link Between Gum Disease, Acute Heart Attacks. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2000/11/001113071724.htm
University Of North Carolina At Chapel Hill. "New Research Finds Link Between Gum Disease, Acute Heart Attacks." ScienceDaily. www.sciencedaily.com/releases/2000/11/001113071724.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins