Featured Research

from universities, journals, and other organizations

Hypothermia For Revived Cardiac Arrest Patients Appears Safe

Date:
October 15, 2001
Source:
American Heart Association
Summary:
Reducing the body temperature of someone revived from cardiac arrest is feasible and safe, but cooling time must be faster to make it a practical treatment, according to a report in Circulation: Journal of the American Heart Association.

DALLAS, Oct. 9 – Reducing the body temperature of someone revived from cardiac arrest is feasible and safe, but cooling time must be faster to make it a practical treatment, according to a report in today’s Circulation: Journal of the American Heart Association.

Related Articles


Those who are revived after cardiac arrest often suffer brain damage because the flow of oxygen to the brain was shut off for too long. "Many surviving patients are left with significant neurological disabilities," says senior author J. C. Grotta, a neurologist at the University of Texas–Houston Medical School. In animal studies, lowering body temperature (hypothermia) has consistently reduced brain injury. The sooner hypothermia begins and the longer it lasts, the less chance for severe neurological damage. Exactly how hypothermia protects the brain is unclear. However, reducing body temperature decreases the brain’s demand for oxygen, reduces the release of nerve-killing chemicals, suppresses inflammation, and stabilizes cell membranes.

Grotta and his colleagues studied nine patients whose cardiac arrests did not occur in the hospital. After acute life support, each patient was sedated and wrapped in two cooling blankets, one around the torso and the other around the pelvis and legs. The goal was to lower body temperature to 33 C (91.4 F) within 120 minutes after initiating cooling and maintaining that temperature for 24 hours.

Four of the patients survived, three of them without neurological disabilities. The fourth survivor went home but required 24-hour supervision due to memory problems. Achieving a body temperature of 33 C proved a slow process taking an average of 301 minutes (1 and hours) in some individuals. Initiating hypothermia in the nine patients took between 40 and 109 minutes, and averaged 78 minutes.

"Much of this time was spent obtaining informed consent," Grotta says. "An average of 46 minutes was required obtaining the patient’s or family’s consent to perform hypothermia treatment." It took an average of 391 minutes (6 hours) from cardiac arrest until the patient’s temperature dropped to 33 C. The time from hypothermia initiation to 33 C took 90 to 690 minutes and averaged 301 minutes (5 hours). "Mild to moderate hypothermia appears feasible and safe, especially when the poor prognosis after cardiac arrest is taken into account," Grotta says. "It warrants further study, but shortening the time to hypothermia will be important in further evaluations." The team did not assess the efficacy of the technique.

The National Institutes of Health supported this research.

Co-authors are R. A. Felberg; M.D.; D.W. Krieger; M.D.; R. Chuang, D.E. Persse M.D.; W. S. Burgin; S.L. Hickenbottom, M.D.; L.B. Morgenstern; M.D. and O. Rosales, M.D.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. "Hypothermia For Revived Cardiac Arrest Patients Appears Safe." ScienceDaily. ScienceDaily, 15 October 2001. <www.sciencedaily.com/releases/2001/10/011015060203.htm>.
American Heart Association. (2001, October 15). Hypothermia For Revived Cardiac Arrest Patients Appears Safe. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2001/10/011015060203.htm
American Heart Association. "Hypothermia For Revived Cardiac Arrest Patients Appears Safe." ScienceDaily. www.sciencedaily.com/releases/2001/10/011015060203.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins