Featured Research

from universities, journals, and other organizations

New Research Adds To Evidence That Acetaminophen May Prevent Colon Cancer In Lab Animals

Date:
April 26, 2002
Source:
New York Medical College
Summary:
Research findings presented at the International Symposium on Antimutagenesis and Anticarcinogenesis at New York Medical College suggest the pain reliever acetaminophen may prevent early biological changes that can lead to colon cancer in laboratory rats.

VALHALLA, N.Y., April 25, 2002 – Research findings presented today at the International Symposium on Antimutagenesis and Anticarcinogenesis at New York Medical College suggest the pain reliever acetaminophen may prevent early biological changes that can lead to colon cancer in laboratory rats.

Related Articles


“In what is considered to be a building body of evidence, we observed that even low levels of acetaminophen showed a powerful protective effect in colon cells exposed to the carcinogen,” said lead researcher Gary M. Williams, M.D., professor of pathology at the College, who noted these findings support those of his earlier research on acetaminophen. Acetaminophen is the active ingredient in Tylenolฎ and other pain relievers.

“The fact that we found this protective effect even in animals exposed to much higher doses of the carcinogen than a human would ever encounter suggests that acetaminophen may have the potential to help prevent the onset of this disease in humans,” Dr. Williams said.

According to Dr. Williams and his colleagues, these findings applied to animals only, and more animal research is needed before humans can be studied in clinical trials. Therefore, they cautioned that as with any medication, people should read the acetaminophen label carefully and use the product only as directed.

In the controlled study by Dr. Williams, test animals were divided into treated animals and controls. Treated animals received acetaminophen prior to their exposure to varying doses of 3,2’-dimethyl-4-aminobiphenyl, a chemical agent linked to colon cancer. Control animals were exposed to the same doses of the carcinogen, or cancer-causing chemical, but were not pretreated at all.

Dr. Williams explained that in animals that were not pretreated with acetaminophen, cellular changes recognized as common precursors to colon cancer were present. In contrast, the animals that were treated with acetaminophen prior to exposure were significantly protected against the cellular effect of the chemical agent.

“In fact, we found that cellular changes indicative of colon cancer were either eliminated or reduced by half in animals pretreated with acetaminophen,” said Dr. Williams.

The research presented at the symposium was sponsored in part by an unrestricted grant from McNeil Consumer & Specialty Pharmaceuticals, makers of Tylenolฎ.


Story Source:

The above story is based on materials provided by New York Medical College. Note: Materials may be edited for content and length.


Cite This Page:

New York Medical College. "New Research Adds To Evidence That Acetaminophen May Prevent Colon Cancer In Lab Animals." ScienceDaily. ScienceDaily, 26 April 2002. <www.sciencedaily.com/releases/2002/04/020426073911.htm>.
New York Medical College. (2002, April 26). New Research Adds To Evidence That Acetaminophen May Prevent Colon Cancer In Lab Animals. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2002/04/020426073911.htm
New York Medical College. "New Research Adds To Evidence That Acetaminophen May Prevent Colon Cancer In Lab Animals." ScienceDaily. www.sciencedaily.com/releases/2002/04/020426073911.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) — A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) — Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) — A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) — Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins