Featured Research

from universities, journals, and other organizations

Advances Developed To Detect Bioterrorist Agents Could Find Use In Protecting Food Supplies

Date:
May 21, 2002
Source:
Lawrence Livermore National Laboratory
Summary:
Technologies developed by Lawrence Livermore National Laboratory researchers and other scientists to fight bioterrorism could find another use — detecting naturally occurring pathogens in food. Technologies developed by Lawrence Livermore National Laboratory researchers and other scientists to fight bioterrorism could find another use — detecting naturally occurring pathogens in food.

SALT LAKE CITY (May 20, 2002) -– Technologies developed by Lawrence Livermore National Laboratory researchers and other scientists to fight bioterrorism could find another use — detecting naturally occurring pathogens in food.

Livermore biomedical scientist Paula McCready will deliver that message today during a session of the American Society for Microbiology at the Salt Palace Convention Center.

"The tools we use to develop DNA signatures for the detection of bioterrorist agents could also be used to search out food-borne pathogens," McCready said. (DNA signatures are areas or regions of DNA unique to specific organisms).

"We believe people are going to look at the problem of food-borne pathogens differently because of the new tools that are becoming available."

Finding the DNA signatures for bacteria that cause food poisoning would allow laboratories to more rapidly identify their presence in food and in the environment.

Among the bacteria that could be identified, according to McCready, are Camphylobacter, a bacterium present in undercooked chicken, or different types of Salmonella, a bacterium that can be found in eggs, juice, fruit or vegetables.

Previously, diagnostic tests to identify and type these bacteria normally required many hours to days to complete because of the need to culture and prepare samples, as well as conduct analysis.

However, with the rapidly growing development of DNA signatures and new polymerase chain reaction (PCR)-based DNA analysis systems, the tests can now be conducted in less than one hour.

"We can also tailor our tests to distinguish harmful forms of different organisms from the benign forms," McCready said.

Livermore researchers and other biomedical scientists have developed highly accurate DNA signatures for the bacteria that cause plague and anthrax, as well as for other organisms.

This work has been done in collaboration with Los Alamos National Laboratory researchers and the Bioterrorism Rapid Response and Advanced Technology Laboratory of the Centers for Disease Control in Atlanta.

During the past year, the Livermore DNA assays have been used to test more than 10,000 complex environmental samples. Individual DNA markers in these assays have been accurate 99.99 percent of the time and the composite pathogen test has been 100 percent accurate, McCready said.

Before breakthroughs in DNA sequencing and other advances, it often required years to find unique DNA signatures to help identify some harmful organisms, McCready said. DNA signatures can now be found in weeks to months.

"The reason this is important is because if a new bug is identified, we can quickly develop DNA signatures for new strains of pathogens," she said.

The use of DNA signatures to detect food-borne diseases would represent another application for the emerging technology. Last year, Livermore’s DNA signatures were used for the first time to detect a public health disease in the environment when collaborators at Northern Arizona University (NAU) used them to detect plague.

In the past, tests to confirm whether plague is present in an environment have usually required seven to 10 days.

Last spring’s finding of plague, in a small rural community northwest of Flagstaff, Ariz., was confirmed within four hours by a team of researchers led by NAU microbiology professor and plague expert Paul Keim.

The Livermore DNA signatures were also used in February as part of a detection system deployed by Los Alamos and Livermore national laboratories at the Salt Lake City Olympic Games.

Designed to detect the criminal use of biological agents, the system is called the Biological Aerosol Sentry and Information System, or BASIS.

Founded in 1952, Lawrence Livermore National Laboratory is a national security laboratory, with a mission to ensure national security and apply science and technology to the important issues of our time. Lawrence Livermore National Laboratory is managed by the University of California for the U.S. Department of Energy’s National Nuclear Security Administration.


Story Source:

The above story is based on materials provided by Lawrence Livermore National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

Lawrence Livermore National Laboratory. "Advances Developed To Detect Bioterrorist Agents Could Find Use In Protecting Food Supplies." ScienceDaily. ScienceDaily, 21 May 2002. <www.sciencedaily.com/releases/2002/05/020521072016.htm>.
Lawrence Livermore National Laboratory. (2002, May 21). Advances Developed To Detect Bioterrorist Agents Could Find Use In Protecting Food Supplies. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2002/05/020521072016.htm
Lawrence Livermore National Laboratory. "Advances Developed To Detect Bioterrorist Agents Could Find Use In Protecting Food Supplies." ScienceDaily. www.sciencedaily.com/releases/2002/05/020521072016.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins