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Drug Used In Treatment Of Alcoholism May Have Role In Treatment Of HIV

Date:
May 30, 2002
Source:
NIH/National Institute On Drug Abuse
Summary:
Naltrexone, a drug used in the treatment of heroin addiction and alcoholism, may increase the effectiveness of the antiretroviral drugs zidovudine (AZT) and indinavir, which are used in the treatment of human immunodeficiency virus (HIV). Naltrexone blocks opioid receptors in the brain preventing the “high” associated with the use of heroin and other opioids. Although the mechanism of the synergistic activity of naltrexone, AZT, and indinavir is unknown, the interaction of naltrexone with opioid receptors may play a role.

Naltrexone, a drug used in the treatment of heroin addiction and alcoholism, may increase the effectiveness of the antiretroviral drugs zidovudine (AZT) and indinavir, which are used in the treatment of human immunodeficiency virus (HIV). Naltrexone blocks opioid receptors in the brain preventing the “high” associated with the use of heroin and other opioids. Although the mechanism of the synergistic activity of naltrexone, AZT, and indinavir is unknown, the interaction of naltrexone with opioid receptors may play a role.


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The above story is based on materials provided by NIH/National Institute On Drug Abuse. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute On Drug Abuse. "Drug Used In Treatment Of Alcoholism May Have Role In Treatment Of HIV." ScienceDaily. ScienceDaily, 30 May 2002. <www.sciencedaily.com/releases/2002/05/020530074106.htm>.
NIH/National Institute On Drug Abuse. (2002, May 30). Drug Used In Treatment Of Alcoholism May Have Role In Treatment Of HIV. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2002/05/020530074106.htm
NIH/National Institute On Drug Abuse. "Drug Used In Treatment Of Alcoholism May Have Role In Treatment Of HIV." ScienceDaily. www.sciencedaily.com/releases/2002/05/020530074106.htm (accessed April 19, 2014).

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