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Researchers Successfully Deliver Drugs To The Primate Brainstem

Date:
October 3, 2002
Source:
NIH/National Institute Of Neurological Disorders And Stroke
Summary:
Current drug treatments of brainstem tumors are largely unsuccessful, because the drugs often fail to bypass the blood vessel lining protecting the brainstem. Now, an NIH study shows that researchers can effectively deliver drugs to the primate brainstem and monitor how the drugs spread inside the brain. The study provides hope for improving treatment of brainstem tumors and other brain diseases.

Current drug treatments of brainstem tumors are largely unsuccessful, because the drugs often fail to bypass the blood vessel lining protecting the brainstem. Now, an NIH study shows that researchers can effectively deliver drugs to the primate brainstem and monitor how the drugs spread inside the brain. The study provides hope for improving treatment of brainstem tumors and other brain diseases. In the new study, researchers at the National Institute of Neurological Disorders and Stroke (NINDS) used a technique called convection-enhanced delivery (CED), which was developed at the National Institutes of Health, to deliver a tracer molecule to the primate brainstem. They then used magnetic resonance imaging (MRI) to track the the tracer's movement throughout the brain. The study appears in the October 2002 issue of the Journal of Neurosurgery.


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The above story is based on materials provided by NIH/National Institute Of Neurological Disorders And Stroke. Note: Materials may be edited for content and length.


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NIH/National Institute Of Neurological Disorders And Stroke. "Researchers Successfully Deliver Drugs To The Primate Brainstem." ScienceDaily. ScienceDaily, 3 October 2002. <www.sciencedaily.com/releases/2002/10/021003075553.htm>.
NIH/National Institute Of Neurological Disorders And Stroke. (2002, October 3). Researchers Successfully Deliver Drugs To The Primate Brainstem. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2002/10/021003075553.htm
NIH/National Institute Of Neurological Disorders And Stroke. "Researchers Successfully Deliver Drugs To The Primate Brainstem." ScienceDaily. www.sciencedaily.com/releases/2002/10/021003075553.htm (accessed April 16, 2014).

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