Featured Research

from universities, journals, and other organizations

Killer Flu Breakthrough: Genome Sciences Centre Sequences SARS Associated Corona Virus

Date:
April 14, 2003
Source:
British Columbia Cancer Agency
Summary:
Scientists at the BC Cancer Agency's Canada's Michael Smith Genome Sciences Centre completed the first publicly available draft sequence for a coronavirus implicated in SARS. "This is a huge step forward in the fight to control the spread of SARS," says Dr. Caroline Astell, projects leader at the Genome Sciences Centre.

April 12, 2003 -- At about 4 a.m. this morning, scientists at the BC Cancer Agency's Canada's Michael Smith Genome Sciences Centre completed the first publicly available draft sequence for a coronavirus implicated in SARS.

Related Articles


"This is a huge step forward in the fight to control the spread of SARS," says Dr. Caroline Astell, projects leader at the Genome Sciences Centre.

Since receiving 1 millionth of a gram of purified viral genetic material from Dr. Frank Plummer at the National Microbiology Lab in Winnipeg, relayed by the BC Centre for Disease Control, scientists at the Genome Sciences Centre have worked around the clock to complete the sequence, using both molecular techniques and state-of-the-art laboratory automation.

"We are very excited about having the ability to do this, and to contribute to a solution for a serious health issue," says Dr. Victor Ling, vice-president, Research, BC Cancer Agency. "I think we can say that we have a rapid-response team who can deal with immediate health concerns."

Dr. Marco Marra, director of the Genome Sciences Centre stated that, "I am delighted that our team of scientists at the Genome Sciences Centre has responded so effectively to the challenge of rapidly sequencing this coronavirus isolate. I am extremely proud of our team. I am similarly impressed by the speed with which viral genomic material was sent to us by Frank Plummer's group a the NML in Winnipeg and by Drs. Bob Brunham and Martin Petric at the BC CDC."

It is expected that this information, posted on the Genome Sciences Centre's website (http://www.bcgsc.bc.ca) as soon as it was generated, will lead to the development of definitive diagnostic tests for SARS. In the longer term, these results may allow scientists to understand why the SARS virus is so deadly, and may assist in the development of an effective vaccine.

Dr. Steven Jones, head of bioinformatics at the Genome Sciences Centre led a team of researchers in assembling the genome from the sequence data. Dr. Jones says the virus detected appears to be a new type of coronavirus bearing only modest similarity to those coronaviruses previously characterized. "The next step for the Genome Sciences Centre is to analyze the proteins that the virus produces, to try and find clues for why this is such a virulent pathogen. With the public release of the sequence data, scientists around the world will also have an opportunity to contribute to this effort" explains Dr. Jones.

Dr. Rob Holt, head of Sequencing at the Genome Sciences Centre, says that while the mandate of the BC Cancer Agency is care and research for cancer, it is significant that the Agency has been working so closely with other organizations to address such an urgent health issue. "This is a stunning convergence of events," says Dr. Holt. "It illustrates what people can achieve when they rally around a common and pressing goal."

While the Genome Sciences Centre is dedicated to cancer research, says Dr. Simon Sutcliffe, president of the BC Cancer Agency, it has been enormously rewarding for the Agency to take the lead in addressing a very important public health crisis.

"We have realized for some time that the study of genomics will be essential to find the causes of, and cures for, cancer," says Dr. Sutcliffe. "This collaborative effort demonstrates that the use of genomics crosses the boundaries of health issues, and gives us the confidence that we'll be able to meet similar challenges in the future."

The BC Cancer Agency, a part of the Provincial Health Services Authority, is committed to reducing the incidence of cancer, reducing the mortality from cancer, and improving the quality of life of those living with cancer. It provides a comprehensive cancer control program for the people of British Columbia by working with community partners to deliver a range of oncology services, including prevention, early detection, diagnosis and treatment, research, education, supportive care, rehabilitation and palliative care. The BC Cancer Research Centre conducts research into the causes and cures for cancer. The Genome Sciences Centre operates with support from the BC Cancer Foundation, Western Economic Diversification, Genome Canada,Genome British Columbia, and the National Institutes of Health (USA)


Story Source:

The above story is based on materials provided by British Columbia Cancer Agency. Note: Materials may be edited for content and length.


Cite This Page:

British Columbia Cancer Agency. "Killer Flu Breakthrough: Genome Sciences Centre Sequences SARS Associated Corona Virus." ScienceDaily. ScienceDaily, 14 April 2003. <www.sciencedaily.com/releases/2003/04/030414090112.htm>.
British Columbia Cancer Agency. (2003, April 14). Killer Flu Breakthrough: Genome Sciences Centre Sequences SARS Associated Corona Virus. ScienceDaily. Retrieved March 3, 2015 from www.sciencedaily.com/releases/2003/04/030414090112.htm
British Columbia Cancer Agency. "Killer Flu Breakthrough: Genome Sciences Centre Sequences SARS Associated Corona Virus." ScienceDaily. www.sciencedaily.com/releases/2003/04/030414090112.htm (accessed March 3, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 3, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Treadmill Test Can Predict Chance Of Death Within A Decade

Treadmill Test Can Predict Chance Of Death Within A Decade

Newsy (Mar. 2, 2015) Johns Hopkins researchers analyzed 58,000 heart stress tests to come up with a formula that predicts a person&apos;s chances of dying in the next decade. Video provided by Newsy
Powered by NewsLook.com
Going Gluten-Free Could Get You A Tax Break

Going Gluten-Free Could Get You A Tax Break

Newsy (Mar. 2, 2015) If a doctor advises you to remove gluten from your diet, you could get a tax deduction on the amount you spend on gluten-free foods. Video provided by Newsy
Powered by NewsLook.com
GlaxoSmithKline and Novartis Try Swapping Success

GlaxoSmithKline and Novartis Try Swapping Success

Reuters - Business Video Online (Mar. 2, 2015) GlaxoSmithKline and Novartis have completed a series of asset swaps worth more than $20 billion. As Grace Pascoe reports they say the deal will reshape both drugmakers. Video provided by Reuters
Powered by NewsLook.com
How Can West Africa Rebuild After Ebola?

How Can West Africa Rebuild After Ebola?

Reuters - Business Video Online (Mar. 2, 2015) How best to rebuild the three West African countries struggling with Ebola will be discussed in Brussels this week. As Hayley Platt reports Sierra Leone has the toughest job ahead - its once thriving economy has been ravaged by the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins