Featured Research

from universities, journals, and other organizations

Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors

Date:
May 9, 2003
Source:
University Of California Irvine
Summary:
A UC Irvine research team has received a five-year, $1.4 million National Institutes of Health grant to develop a microscopic probe for detecting and treating pre-cancerous and malignant tumors in humans.

A UC Irvine research team has received a five-year, $1.4 million National Institutes of Health grant to develop a microscopic probe for detecting and treating pre-cancerous and malignant tumors in humans.

Similar to the miniaturized vessel that explores a human body in the science fiction movie “Fantastic Voyage,” this nano-sized probe would be inserted into a patient and then guided through the esophagus, stomach and colon to determine if tumors are growing on the wall of the intestine. The probe would be remotely controlled by a surgeon operating a device called an endoscope.

If successful, the probe would be used for the early diagnosis of cancers and pre-cancers of the gastrointestinal system. Researchers will test the probe in pigs and human volunteers to determine its effectiveness and safety.

“Currently, gastrointestinal cancers and other diseases are diagnosed only by visual inspection of the intestine’s surface,” said Dr. Kenneth Chang, director of the H.H. Chao Comprehensive Digestive Disease Center at UCI. “Early stage cancer screening is difficult because you’re looking for microscopic changes. An optical nanoprobe could help pinpoint those changes before they turn into advanced cancer. It also may allow physicians to circumvent traditional biopsies that require removing tissues by providing an optical, or virtual, biopsy sampling of much larger areas.”

To view a tumor, the probe incorporates a technology called optical coherence tomography. This technology can create a visual impression of tissue structure and blood flow with a sharpness not possible using current scanning methods.

“We have developed optical coherence tomography techniques that can show, in detail, blood flow through tiny vessels as well as microscopic changes in tissue,” said Zhongping Chen, associate professor of biomedical engineering at UCI’s Beckman Laser Institute. “By coupling this imaging technology with a scanning microdevice that we can control with an endoscope, we may have arrived at an effective alternative to biopsy and visual screening for cancer.”

Chen, Chang and their colleagues will divide into four teams to focus on:

• creating techniques for high-speed, high-resolution imaging on a scanner;

• creating a microscopic mechanical probe from silicon, which has been used for making microscopic computer chips and other technological devices;

• creating mechanical probes from plastic polymers, a new area that is showing some promise in making durable, tiny scientific and medical instruments;

• and instituting clinical trials to test the capabilities of the imaging and mechanical probes in humans.

The researchers’ colleagues include Guann-Pyng Li and Mark Bachman from UCI’s Henry Samueli School of Engineering and Norman Tien of UC Davis.


Story Source:

The above story is based on materials provided by University Of California Irvine. Note: Materials may be edited for content and length.


Cite This Page:

University Of California Irvine. "Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors." ScienceDaily. ScienceDaily, 9 May 2003. <www.sciencedaily.com/releases/2003/05/030509085108.htm>.
University Of California Irvine. (2003, May 9). Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2003/05/030509085108.htm
University Of California Irvine. "Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors." ScienceDaily. www.sciencedaily.com/releases/2003/05/030509085108.htm (accessed August 30, 2014).

Share This




More Matter & Energy News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Australian Airlines Relax Phone Ban Too

Australian Airlines Relax Phone Ban Too

Reuters - Business Video Online (Aug. 26, 2014) Qantas and Virgin say passengers can use their smartphones and tablets throughout flights after a regulator relaxed a ban on electronic devices during take-off and landing. As Hayley Platt reports the move comes as the two domestic rivals are expected to post annual net losses later this week. Video provided by Reuters
Powered by NewsLook.com
Hurricane Marie Brings Big Waves to California Coast

Hurricane Marie Brings Big Waves to California Coast

Reuters - US Online Video (Aug. 26, 2014) Huge waves generated by Hurricane Marie hit the Southern California coast. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Chinese Researchers Might Be Creating Supersonic Submarine

Chinese Researchers Might Be Creating Supersonic Submarine

Newsy (Aug. 26, 2014) Chinese researchers have expanded on Cold War-era tech and are closer to building a submarine that could reach the speed of sound. Video provided by Newsy
Powered by NewsLook.com
Breakingviews: India Coal Strained by Supreme Court Ruling

Breakingviews: India Coal Strained by Supreme Court Ruling

Reuters - Business Video Online (Aug. 26, 2014) An acute coal shortage is likely to be aggravated as India's supreme court declared government coal allocations illegal, says Breakingviews' Peter Thal Larsen. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins