Featured Research

from universities, journals, and other organizations

Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors

Date:
May 9, 2003
Source:
University Of California Irvine
Summary:
A UC Irvine research team has received a five-year, $1.4 million National Institutes of Health grant to develop a microscopic probe for detecting and treating pre-cancerous and malignant tumors in humans.

A UC Irvine research team has received a five-year, $1.4 million National Institutes of Health grant to develop a microscopic probe for detecting and treating pre-cancerous and malignant tumors in humans.

Related Articles


Similar to the miniaturized vessel that explores a human body in the science fiction movie “Fantastic Voyage,” this nano-sized probe would be inserted into a patient and then guided through the esophagus, stomach and colon to determine if tumors are growing on the wall of the intestine. The probe would be remotely controlled by a surgeon operating a device called an endoscope.

If successful, the probe would be used for the early diagnosis of cancers and pre-cancers of the gastrointestinal system. Researchers will test the probe in pigs and human volunteers to determine its effectiveness and safety.

“Currently, gastrointestinal cancers and other diseases are diagnosed only by visual inspection of the intestine’s surface,” said Dr. Kenneth Chang, director of the H.H. Chao Comprehensive Digestive Disease Center at UCI. “Early stage cancer screening is difficult because you’re looking for microscopic changes. An optical nanoprobe could help pinpoint those changes before they turn into advanced cancer. It also may allow physicians to circumvent traditional biopsies that require removing tissues by providing an optical, or virtual, biopsy sampling of much larger areas.”

To view a tumor, the probe incorporates a technology called optical coherence tomography. This technology can create a visual impression of tissue structure and blood flow with a sharpness not possible using current scanning methods.

“We have developed optical coherence tomography techniques that can show, in detail, blood flow through tiny vessels as well as microscopic changes in tissue,” said Zhongping Chen, associate professor of biomedical engineering at UCI’s Beckman Laser Institute. “By coupling this imaging technology with a scanning microdevice that we can control with an endoscope, we may have arrived at an effective alternative to biopsy and visual screening for cancer.”

Chen, Chang and their colleagues will divide into four teams to focus on:

• creating techniques for high-speed, high-resolution imaging on a scanner;

• creating a microscopic mechanical probe from silicon, which has been used for making microscopic computer chips and other technological devices;

• creating mechanical probes from plastic polymers, a new area that is showing some promise in making durable, tiny scientific and medical instruments;

• and instituting clinical trials to test the capabilities of the imaging and mechanical probes in humans.

The researchers’ colleagues include Guann-Pyng Li and Mark Bachman from UCI’s Henry Samueli School of Engineering and Norman Tien of UC Davis.


Story Source:

The above story is based on materials provided by University Of California Irvine. Note: Materials may be edited for content and length.


Cite This Page:

University Of California Irvine. "Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors." ScienceDaily. ScienceDaily, 9 May 2003. <www.sciencedaily.com/releases/2003/05/030509085108.htm>.
University Of California Irvine. (2003, May 9). Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors. ScienceDaily. Retrieved April 21, 2015 from www.sciencedaily.com/releases/2003/05/030509085108.htm
University Of California Irvine. "Nanoprobe To Be Developed For A 'Fantastic Voyage' In The Human Body, Finding And Treating Deadly Tumors." ScienceDaily. www.sciencedaily.com/releases/2003/05/030509085108.htm (accessed April 21, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Tuesday, April 21, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Free Home Heating Offered by E-Radiators

Free Home Heating Offered by E-Radiators

Reuters - Innovations Video Online (Apr. 21, 2015) A revolutionary new radiator design offers Dutch home-owners the chance to get free heating. The e-Radiator is a computer server modified so that the heat it generates can warm a room inside a house. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Humanoid Robot Can Recognise and Interact With People

Humanoid Robot Can Recognise and Interact With People

Reuters - Innovations Video Online (Apr. 20, 2015) An ultra-realistic humanoid robot called &apos;Han&apos; recognises and interprets people&apos;s facial expressions and can even hold simple conversations. Developers Hanson Robotics hope androids like Han could have uses in hospitality and health care industries where face-to-face communication is vital. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Drones and Health Apps at Santiago's "Robotics Day"

Drones and Health Apps at Santiago's "Robotics Day"

AFP (Apr. 20, 2015) Latin American robotics experts gather in Santiago, Chile for "Robotics Day". Video provided by AFP
Powered by NewsLook.com
Japan Humanoid Robot Receives Customers at Department Store

Japan Humanoid Robot Receives Customers at Department Store

AFP (Apr. 20, 2015) She can smile, she can sing and she can give you guidance at one of the most upscale department stores in Tokyo...a female-looking humanoid makes her debut as a receptionist Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins