Featured Research

from universities, journals, and other organizations

Researchers Detect Receptor For Day/Night Cycles

Date:
June 24, 2003
Source:
University Of Toronto
Summary:
It's been something of a mystery to scientists - how are blind mice able to synchronize their biological rhythms to day and night? New research by a team of scientists, including one from the University of Toronto, seems to have uncovered the answer.

It's been something of a mystery to scientists - how are blind mice able to synchronize their biological rhythms to day and night? New research by a team of scientists, including one from the University of Toronto, seems to have uncovered the answer.

Related Articles


Rods and cones in the outer retina are the eyes' main photoreceptors, explains Nicholas Mrosovsky, professor emeritus in zoology at U of T. When these rods and cones degenerate, mammals and animals become blind. Despite this, however, some animals can synchronize their biological clocks to the day/night cycle, a problem that has perplexed scientists for the past decade.

"We believed there must be some other specialized receptor for detecting night and day. We now have evidence that this long sought-after photoreceptor is a layer of cells, located in the inner retina, that contain melanopsin, a pigment chemically related to other opsins [a type of protein] found in the rods and cones of the outer retina."

In their study, the researchers deleted melanopsin from the inner retinal cells of transgenic mice. Mrosovsky found that melanopsin-free mice could not synchronize their biological rhythms to day/night cycles or react normally to light stimuli. This research may be applicable to humans who are blind but who have the melanopsin receptor. They may still be able to synchronize their biological rhythms, he says.

Recently published online in Nature, this research was supported by the U.S. National Eye Institute, the U.K. Biotechnology and Biological Sciences Research Council, the Wellcome Trust and the Canadian Institutes of Health Research.


Story Source:

The above story is based on materials provided by University Of Toronto. Note: Materials may be edited for content and length.


Cite This Page:

University Of Toronto. "Researchers Detect Receptor For Day/Night Cycles." ScienceDaily. ScienceDaily, 24 June 2003. <www.sciencedaily.com/releases/2003/06/030624085358.htm>.
University Of Toronto. (2003, June 24). Researchers Detect Receptor For Day/Night Cycles. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2003/06/030624085358.htm
University Of Toronto. "Researchers Detect Receptor For Day/Night Cycles." ScienceDaily. www.sciencedaily.com/releases/2003/06/030624085358.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins