Featured Research

from universities, journals, and other organizations

Aspirin Could Reduce The Risk Of Deadly Infections

Date:
July 18, 2003
Source:
Dartmouth Medical School
Summary:
Adding to the long list of the benefits of aspirin, researchers have found that it is responsible for reducing toxic bacteria associated with serious infections. A study led by Dartmouth Medical School describes how salicylic acid-produced when the body breaks down aspirin-disrupts the bacteria's ability to adhere to host tissue, reducing the threat of deadly infections.

HANOVER, NH -- Adding to the long list of the benefits of aspirin, researchers have found that it is responsible for reducing toxic bacteria associated with serious infections. A study led by Dartmouth Medical School describes how salicylic acid-produced when the body breaks down aspirin-disrupts the bacteria's ability to adhere to host tissue, reducing the threat of deadly infections.

The investigation, which appears in the July 15 issue of the Journal of Clinical Investigation, focused on the bacterium Staphylococcus aureus, and its role in infections in animal tissue. S. aureus is a leading cause of serious systemic (often referred to as staph) infections and abscesses.

"Our research shows that salicylic acid, a byproduct of aspirin, impacted the stress system of the bacteria and reduced its ability to cause infection," said lead author Dr. Ambrose Cheung, a professor of microbiology and immunology at Dartmouth Medical School.

By disrupting this stress system, aspirin reduced the bacteria's capacity to adhere to host tissue. In addition, the salicylic acid disrupted the ability of S. aureus to produce toxins, which the bacteria require to propagate and spread to other tissue. As a result, the animals treated with aspirin have smaller abscesses and they have fewer number of bacteria in the infection. Aspirin did not cure it, notes Cheung, but it reduced the ability of the bacteria to cause infection.

The S. aureus bacteria are also responsible for sepsis, a blood poisoning disease that strikes 750,000 people in the US annually and is the leading cause of death in America's non-coronary intensive care units. Cases of sepsis are growing in number each year and are becoming increasingly resistant to antibiotics, making aspirin a possibly invaluable option for treatment.

"The fact that aspirin has been used for pain treatment, to reduce mortality due to heart attacks, and can possibly reduce the risks of infection is incredible," said Cheung. "We look forward to conducting future tests with aspirin in conjunction with antibiotic therapy."


Story Source:

The above story is based on materials provided by Dartmouth Medical School. Note: Materials may be edited for content and length.


Cite This Page:

Dartmouth Medical School. "Aspirin Could Reduce The Risk Of Deadly Infections." ScienceDaily. ScienceDaily, 18 July 2003. <www.sciencedaily.com/releases/2003/07/030718083746.htm>.
Dartmouth Medical School. (2003, July 18). Aspirin Could Reduce The Risk Of Deadly Infections. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2003/07/030718083746.htm
Dartmouth Medical School. "Aspirin Could Reduce The Risk Of Deadly Infections." ScienceDaily. www.sciencedaily.com/releases/2003/07/030718083746.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins