Featured Research

from universities, journals, and other organizations

Lowering Blood Pressure Immediately After Stroke Can Be Harmful

Date:
October 28, 2003
Source:
American Academy Of Neurology
Summary:
Lowering blood pressure in the first 24 hours following a stroke can be harmful to recovery, according to a study published in the October 28 issue of Neurology, the scientific journal of the American Academy of Neurology.

ST. PAUL, MN – Lowering blood pressure in the first 24 hours following a stroke can be harmful to recovery, according to a study published in the October 28 issue of Neurology, the scientific journal of the American Academy of Neurology.

Related Articles


A team in Brazil studied blood pressure in 115 stroke patients. The average blood pressure upon hospital admission was 160/94 mm Hg (mercury). Blood pressure dropped in all patients – either spontaneously or with medication – during the first 24 hours after stroke (the acute phase). At follow-up three months later, 44 patients had a poor outcome, meaning at least moderate disability. They needed assistance to complete daily activities like walking, eating or grooming. The risk of poor outcome increased almost twofold with every 10 percent decrease in systolic blood pressure (the top number) during the first 24 hours.

Systolic blood pressure varied an average of 31 percent in the poor outcome group during the first 24 hours, compared to an average of 26 percent in the other patients. When blood pressure drops a lot in the acute phase, the blood flow to brain tissue is reduced, which can cause more damage.

"The amount of blood pressure variation made the difference between a poor outcome and a good one," said neurologist and lead author Jamary Oliveira-Filho, MD, PhD, of the Hospital Sao Rafael and the Federal University of Bahia in Salvador, Brazil. "Blood pressure is only one variable in the outcome, but even small changes can make a difference in the big picture."

An editorial in the same issue of Neurology says that despite limitations, the study adds to the discussion of risk vs. benefit in lowering blood pressure immediately after stroke.

"While 'lower is better' for preventing first and subsequent strokes, there is a growing sentiment that 'high is good' in the acute phase," said neurologist and editorial author Karen C. Johnston, MD, MSc, of the University of Virginia Health System, Charlottesville, Va. "Blood pressure reduction in the acute phase should be avoided if at all possible."

The study found no significant link between stroke severity and the amount that blood pressure dropped. There was no difference in outcome whether blood pressure decreased spontaneously or with medication during the first 24 hours, which suggests that even a spontaneous decrease can be harmful to brain tissue.

Oliveira-Filho and Johnston both noted the need for a randomized trial to study whether it is appropriate to treat blood pressure in the first 24 hours.

"The question of what is the ideal blood pressure in the acute phase remains a controversy," said Oliveira-Filho.

Blood pressure is considered normal when the top number (systolic) is less than 140 and the bottom number (diastolic) is less than 90. When blood pressure is greater than or equal to these numbers, the result is hypertension, the major risk factor for stroke.

###

The American Academy of Neurology, an association of more than 18,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer's disease, epilepsy, Parkinson's disease, autism and multiple sclerosis.

For more information about the American Academy of Neurology, visit its web site at http://www.aan.com.


Story Source:

The above story is based on materials provided by American Academy Of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy Of Neurology. "Lowering Blood Pressure Immediately After Stroke Can Be Harmful." ScienceDaily. ScienceDaily, 28 October 2003. <www.sciencedaily.com/releases/2003/10/031028060809.htm>.
American Academy Of Neurology. (2003, October 28). Lowering Blood Pressure Immediately After Stroke Can Be Harmful. ScienceDaily. Retrieved January 28, 2015 from www.sciencedaily.com/releases/2003/10/031028060809.htm
American Academy Of Neurology. "Lowering Blood Pressure Immediately After Stroke Can Be Harmful." ScienceDaily. www.sciencedaily.com/releases/2003/10/031028060809.htm (accessed January 28, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, January 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Malnutrition on the Rise as Violence Flares in C. Africa

Malnutrition on the Rise as Violence Flares in C. Africa

AFP (Jan. 28, 2015) Violence can flare up at any moment in Bambari with only a bridge separating Muslims and Christians. Malnutrition is on the rise and lack of water means simple cooking fires threaten to destroy makeshift camps where people are living. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Poultry Culled in Taiwan to Thwart Bird Flu

Poultry Culled in Taiwan to Thwart Bird Flu

Reuters - News Video Online (Jan. 28, 2015) Taiwan culls over a million poultry in efforts to halt various strains of avian flu. Julie Noce reports. Video provided by Reuters
Powered by NewsLook.com
Media Criticizing Parents For Not Vaccinating Children

Media Criticizing Parents For Not Vaccinating Children

Newsy (Jan. 28, 2015) As the Disneyland measles outbreak continues to spread, the media says parents who choose not to vaccinate their children are part of the cause. Video provided by Newsy
Powered by NewsLook.com
Shark Bite Victim Making Amazing Recovery

Shark Bite Victim Making Amazing Recovery

AP (Jan. 27, 2015) A Texas woman who lost more than five pounds of flesh to a shark in the Bahamas earlier this month could be released from a Florida hospital soon. Experts believe she was bitten by a bull shark while snorkeling. (Jan. 27) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins