Featured Research

from universities, journals, and other organizations

Arteries Clog Earlier In People With Lupus, Says New Study

Date:
December 22, 2003
Source:
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases
Summary:
People with the autoimmune disease lupus may develop carotid atherosclerosis (the buildup of fatty deposits in the arteries) at an accelerated rate and independently of many risk factors normally associated with cardiovascular disease, according to a new study supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases.

People with the autoimmune disease lupus may develop carotid atherosclerosis (the buildup of fatty deposits in the arteries) at an accelerated rate and independently of many risk factors normally associated with cardiovascular disease, according to a new study supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health. The work was reported in the December 18 issue of the New England Journal of Medicine.

Related Articles


The study, carried out by Mary J. Roman, M.D., at Weill Medical College of Cornell University, Jane E. Salmon, M.D., at the Hospital for Special Surgery (N.Y.), and their colleagues examined 197 people with lupus and the same number of matched controls. Risk factors for cardiovascular disease, including family history of heart disease, cholesterol levels, smoking and hypertension, were similar in both groups, but atherosclerosis, as evidenced by carotid ultrasound, was more prevalent in lupus patients. The scientists also found that people with lupus who had the disease longer, had more damage from the disease, and had used less of the immunosuppressive drug cyclophosphamide to treat it were more likely to develop fatty deposits in their arteries.

"Although we've known for some time that there is an association between lupus and premature heart attacks," said NIAMS Director Stephen I. Katz, M.D., Ph.D. "until now we haven't understood well the reasons. This study gives us a basis to pursue intervention strategies for reducing cardiovascular risks."

Lupus (systemic lupus erythematosus) is a rheumatic disease that can affect many parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels and brain. People who have lupus may have many different symptoms, but some of the most common ones include extreme fatigue, painful or swollen joints (arthritis), unexplained fever, skin rashes and kidney problems. Many more women than men have lupus. It is three times more common in African American women than in Caucasian women and is also more common in women of Hispanic, Asian and Native American descent.

###

Funding for this study was also provided by the National Heart, Lung, and Blood Institute and the National Center on Minority Health and Health Disparities, which along with NIAMS are parts of the Department of Health and Human Services' (DHHS) National Institutes of Health; DHHS' Public Health Service; the Mary Kirkland Center for Lupus Research at the Hospital for Special Surgery; and the Bugher Foundation.


Story Source:

The above story is based on materials provided by NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. "Arteries Clog Earlier In People With Lupus, Says New Study." ScienceDaily. ScienceDaily, 22 December 2003. <www.sciencedaily.com/releases/2003/12/031219073140.htm>.
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. (2003, December 22). Arteries Clog Earlier In People With Lupus, Says New Study. ScienceDaily. Retrieved March 26, 2015 from www.sciencedaily.com/releases/2003/12/031219073140.htm
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. "Arteries Clog Earlier In People With Lupus, Says New Study." ScienceDaily. www.sciencedaily.com/releases/2003/12/031219073140.htm (accessed March 26, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 26, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com
AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com
Obama: Affordable Care Act 'saving Lives'

Obama: Affordable Care Act 'saving Lives'

AP (Mar. 25, 2015) Speaking at a White House event marking the fifth anniversary of the Affordable Care Act, President Barack Obama says the law is "saving lives that touch all of us." (March 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins