Featured Research

from universities, journals, and other organizations

Arteries Clog Earlier In People With Lupus, Says New Study

Date:
December 22, 2003
Source:
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases
Summary:
People with the autoimmune disease lupus may develop carotid atherosclerosis (the buildup of fatty deposits in the arteries) at an accelerated rate and independently of many risk factors normally associated with cardiovascular disease, according to a new study supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases.

People with the autoimmune disease lupus may develop carotid atherosclerosis (the buildup of fatty deposits in the arteries) at an accelerated rate and independently of many risk factors normally associated with cardiovascular disease, according to a new study supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health. The work was reported in the December 18 issue of the New England Journal of Medicine.

The study, carried out by Mary J. Roman, M.D., at Weill Medical College of Cornell University, Jane E. Salmon, M.D., at the Hospital for Special Surgery (N.Y.), and their colleagues examined 197 people with lupus and the same number of matched controls. Risk factors for cardiovascular disease, including family history of heart disease, cholesterol levels, smoking and hypertension, were similar in both groups, but atherosclerosis, as evidenced by carotid ultrasound, was more prevalent in lupus patients. The scientists also found that people with lupus who had the disease longer, had more damage from the disease, and had used less of the immunosuppressive drug cyclophosphamide to treat it were more likely to develop fatty deposits in their arteries.

"Although we've known for some time that there is an association between lupus and premature heart attacks," said NIAMS Director Stephen I. Katz, M.D., Ph.D. "until now we haven't understood well the reasons. This study gives us a basis to pursue intervention strategies for reducing cardiovascular risks."

Lupus (systemic lupus erythematosus) is a rheumatic disease that can affect many parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels and brain. People who have lupus may have many different symptoms, but some of the most common ones include extreme fatigue, painful or swollen joints (arthritis), unexplained fever, skin rashes and kidney problems. Many more women than men have lupus. It is three times more common in African American women than in Caucasian women and is also more common in women of Hispanic, Asian and Native American descent.

###

Funding for this study was also provided by the National Heart, Lung, and Blood Institute and the National Center on Minority Health and Health Disparities, which along with NIAMS are parts of the Department of Health and Human Services' (DHHS) National Institutes of Health; DHHS' Public Health Service; the Mary Kirkland Center for Lupus Research at the Hospital for Special Surgery; and the Bugher Foundation.


Story Source:

The above story is based on materials provided by NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. "Arteries Clog Earlier In People With Lupus, Says New Study." ScienceDaily. ScienceDaily, 22 December 2003. <www.sciencedaily.com/releases/2003/12/031219073140.htm>.
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. (2003, December 22). Arteries Clog Earlier In People With Lupus, Says New Study. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2003/12/031219073140.htm
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. "Arteries Clog Earlier In People With Lupus, Says New Study." ScienceDaily. www.sciencedaily.com/releases/2003/12/031219073140.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins