Featured Research

from universities, journals, and other organizations

Insulin-producing Cells Found In A Variety Of Tissues In Diabetes

Date:
February 18, 2004
Source:
Baylor College Of Medicine
Summary:
Cells that produce insulin have been unexpectedly found in the fat, liver and bone marrow of diabetic mice, said researchers at Baylor College of Medicine (BCM) in a report that appeared today in the Proceedings of the National Academy of Sciences.

HOUSTON -- (Feb. 17, 2004) -- Cells that produce insulin have been unexpectedly found in the fat, liver and bone marrow of diabetic mice, said researchers at Baylor College of Medicine (BCM) in a report that appeared today in the Proceedings of the National Academy of Sciences.

Related Articles


"In fact, the appearance of insulin-producing cells occurs in both type 1 (juvenile) and type 2 (adult-onset) diabetic mice," said Dr. Lawrence Chan, chief of the BCM endocrinology section and professor in the department of medicine and molecular and cellular biology.

"The common denominator in all the animals is high blood sugar, not insulin-deficiency," he said. "High blood sugar causes these cells to produce insulin."

The numbers of cells and the amount of insulin produced are both very small and do not seem to ameliorate the animals' disease, said Chan.

He found that the source of the insulin-producing cells is the bone marrow, which had been identified as the origin of many different kinds of tissues in recent years. He and his colleagues were surprised that only a brief three-day period of high blood glucose was sufficient to nudge the cells outside the pancreas to produce insulin.

If this inherent property of cells can be harnessed and augmented, Chan speculates, scientists could it to generate insulin-producing cells from other tissues for the treatment of diabetes. If the production of insulin by cells outside the pancreas affects the immune system, which goes awry in people predisposed to type 1 diabetes, it could affect the course of the disease.


Story Source:

The above story is based on materials provided by Baylor College Of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Baylor College Of Medicine. "Insulin-producing Cells Found In A Variety Of Tissues In Diabetes." ScienceDaily. ScienceDaily, 18 February 2004. <www.sciencedaily.com/releases/2004/02/040218074822.htm>.
Baylor College Of Medicine. (2004, February 18). Insulin-producing Cells Found In A Variety Of Tissues In Diabetes. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2004/02/040218074822.htm
Baylor College Of Medicine. "Insulin-producing Cells Found In A Variety Of Tissues In Diabetes." ScienceDaily. www.sciencedaily.com/releases/2004/02/040218074822.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins