Featured Research

from universities, journals, and other organizations

Imaging Test Could Be Used To Diagnose Schizophrenia

Date:
April 26, 2004
Source:
Yale University
Summary:
An abnormal pattern in an area of the brain that governs hearing may be an accurate method of diagnosing schizophrenia, according to a study by Yale researchers and collaborators.

New Haven, Conn. -- An abnormal pattern in an area of the brain that governs hearing may be an accurate method of diagnosing schizophrenia, according to a study by Yale researchers and collaborators.

"These results seem to point to a cardinal abnormality in schizophrenia," said Godfrey Pearlson, M.D., professor of psychiatry at Yale School of Medicine, director of the Olin Neuropsychiatry Research Center at the Institute of Living in Hartford, and senior author of the study published in Biological Psychiatry. "Using this imaging test, we were able to identify patients with schizophrenia with 97 percent accuracy."

Pearlson, Vince Calhoun and Kent Kiehl later replicated their initial finding with an independent sample and achieved a 94 percent rate of accuracy. Calhoun and Kiehl have appointments at the Olin Center and Yale.

Currently, the clinical diagnosis of schizophrenia is based on a constellation of psychiatric symptoms. The mental illness also has been associated with both structural and functional abnormalities in neocortical networks including frontal, parietal, and temporal regions of the brain, but there has been no diagnostic test for the disorder.

Abnormalities in auditory cortex structure and function are prominent features of the brains in persons with schizophrenia, particularly in the superior temporal gyrus (SRG). Reduction in size of the SRG may correlate with the severity of auditory hallucinations and of formal thought disorder. However, all of these previously documented anatomic differences overlap significantly with those of healthy controls and are thus not useful for diagnosis.

"Therefore, this newly reported functional brain change results in almost total separation of patients and healthy controls in two independent samples, and thus has possible diagnostic utility," Pearlson said.

Data were collected from two locations. One group consisted of 17 outpatients with chronic schizophrenia matched with 17 healthy persons in Vancouver, B.C. Another group consisted of eight patients and eight healthy persons in Hartford, Conn.

"These results have the potential to provide a powerful, quantitative clinical tool for the assessment of schizophrenia," Pearlson said.

Citation: Biological Psychiatry, Vol. 55 (8): 842-849, April 15, 2004


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Imaging Test Could Be Used To Diagnose Schizophrenia." ScienceDaily. ScienceDaily, 26 April 2004. <www.sciencedaily.com/releases/2004/04/040426055317.htm>.
Yale University. (2004, April 26). Imaging Test Could Be Used To Diagnose Schizophrenia. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2004/04/040426055317.htm
Yale University. "Imaging Test Could Be Used To Diagnose Schizophrenia." ScienceDaily. www.sciencedaily.com/releases/2004/04/040426055317.htm (accessed July 30, 2014).

Share This




More Mind & Brain News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

It's Not Just Facebook: OKCupid Experiments With Users Too

It's Not Just Facebook: OKCupid Experiments With Users Too

Newsy (July 29, 2014) If you've been looking for love online, there's a chance somebody has been looking at how you're looking. Video provided by Newsy
Powered by NewsLook.com
How Your Face Can Leave A Good Or Bad First Impression

How Your Face Can Leave A Good Or Bad First Impression

Newsy (July 29, 2014) Researchers have found certain facial features can make us seem more attractive or trustworthy. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com
University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins